1. 2019
  2. Effect of chiral polyhydrochromenes on cannabinoid system

    Li-Zhulanov, N. S., Il’ina, I. V., Chicca, A., Schenker, P., Patrusheva, O. S., Nazimova, E. V., Korchagina, D. V., Krasavin, M., Volcho, K. P. & Salakhutdinov, N. F., Apr 2019, In: Medicinal Chemistry Research. 28, 4, p. 450-464 15 p.

    Research output: Contribution to journalArticlepeer-review

  3. Antimetastatic Activity of Combined Topotecan and Tyrosyl-DNA Phosphodiesterase-1 Inhibitor on Modeled Lewis Lung Carcinoma

    Koldysheva, E. V., Men’shchikova, A. P., Lushnikova, E. L., Popova, N. A., Kaledin, V. I., Nikolin, V. P., Zakharenko, A. L., Luzina, O. A., Salakhutdinov, N. F. & Lavrik, O. I., 15 Mar 2019, In: Bulletin of Experimental Biology and Medicine. 166, 5, p. 661-666 6 p.

    Research output: Contribution to journalArticlepeer-review

  4. Synthesis of diazaadamantanes from 1,5-dimethylbispidinone and some natural ketones

    Suslov, E. V., Ponomarev, K. Y., Korchagina, D. V., Volcho, K. P. & Salakhutdinov, N. F., 1 Mar 2019, In: Russian Chemical Bulletin. 68, 3, p. 601-605 5 p.

    Research output: Contribution to journalArticlepeer-review

  5. Increasing bioavailability of very poorly water-soluble compounds. A case study of an anti-tumor drug, soloxolon methyl

    Ogienko, A. G., Markov, A. V., Sen'kova, A. V., Logashenko, E. B., Salomatina, O. V., Myz, S. A., Ogienko, A. A., Nefedov, A. A., Losev, E. A., Drebushchak, T. N., Salakhutdinov, N. F., Boldyrev, V. V., Vlasov, V. V., Zenkova, M. A. & Boldyreva, E. V., 1 Feb 2019, In: Journal of Drug Delivery Science and Technology. 49, p. 35-42 8 p.

    Research output: Contribution to journalArticlepeer-review

  6. Inhibitory Effect of New Semisynthetic Usnic Acid Derivatives on Human Tyrosyl-DNA Phosphodiesterase 1

    Dyrkheeva, N., Luzina, O., Filimonov, A., Zakharova, O., Ilina, E., Zakharenko, A., Kuprushkin, M., Nilov, D., Gushchina, I., Švedas, V., Salakhutdinov, N. & Lavrik, O., 1 Jan 2019, In: Planta Medica. 85, 2, p. 103-111 9 p.

    Research output: Contribution to journalArticlepeer-review

  7. Neuroregeneration in Parkinson's Disease: From Proteins to Small Molecules

    Sidorova, Y. A., Volcho, K. P. & Salakhutdinov, N. F., 1 Jan 2019, In: Current Neuropharmacology. 17, 3, p. 268-287 20 p.

    Research output: Contribution to journalReview articlepeer-review

  8. Novel inhibitors of DNA repair enzyme TDP1 combining monoterpenoid and adamantane fragments

    Mozhaitsev, E. S., Zakharenko, A. L., Suslov, E. V., Korchagina, D. V., Zakharova, O. D., Vasil’eva, I. A., Chepanova, A. A., Black, E., Patel, J., Chand, R., Reynisson, J., Leung, I. K. H., Volcho, K. P., Salakhutdinov, N. F. & Lavrik, O. I., 1 Jan 2019, In: Anti-Cancer Agents in Medicinal Chemistry. 19, 4, p. 463-472 10 p.

    Research output: Contribution to journalArticlepeer-review

  9. Novel tyrosyl-DNA phosphodiesterase 1 inhibitors enhance the therapeutic impact of topoteсan on in vivo tumor models

    Zakharenko, A. L., Luzina, O. A., Sokolov, D. N., Kaledin, V. I., Nikolin, V. P., Popova, N. A., Patel, J., Zakharova, O. D., Chepanova, A. A., Zafar, A., Reynisson, J., Leung, E., Leung, I. K. H., Volcho, K. P., Salakhutdinov, N. F. & Lavrik, O. I., 1 Jan 2019, In: European Journal of Medicinal Chemistry. 161, p. 581-593 13 p.

    Research output: Contribution to journalArticlepeer-review

  10. The development of tyrosyl-DNA phosphodyesterase 1 (TDP1) inhibitors based on the amines combining aromatic/heteroaromatic and monoterpenoid moieties

    Mozhaitsev, E., Suslov, E., Demidova, Y., Korchagina, D., Volcho, K., Zakharenko, A., Vasil’eva, I., Kupryushkin, M., Chepanova, A., Ayine-Tora, D. M., Reynisson, J., Salakhutdinov, N. & Lavrik, O., 1 Jan 2019, In: Letters in Drug Design and Discovery. 16, 5, p. 597-605 9 p.

    Research output: Contribution to journalArticlepeer-review

  11. Effects of acute and chronic treatment of STEP inhibitor, TC-2153, on the nervous system and behaviour of zebrafish (Danio rerio)

    Kulikov, A., Sinyakova, N., Kulikova, E., Evglevsky, N., Kolotygin, I., Volcho, K., Salakhutdinov, N., Kulikov, V., Romaschenko, A. & Moshkin, M., 2019, In: European Neuropsychopharmacology. 29, p. S198-S199 2 p.

    Research output: Contribution to journalMeeting Abstractpeer-review

  12. 2018
  13. Molecular and Supramolecular Structure of 8-(Trifluoromethyl)Benzo[f][1,2,3,4,5] Pentathiepin-6-Amine – A Representative of Condensed Arene Pentathiepines

    Rybalova, T. V., Rogachev, A. D., Khomenko, T. M., Volcho, K. P. & Salakhutdinov, N. F., 1 Dec 2018, In: Journal of Structural Chemistry. 59, 7, p. 1753-1758 6 p.

    Research output: Contribution to journalArticlepeer-review

  14. Synthesis of d-(+)-camphor-based: N -acylhydrazones and their antiviral activity

    Kovaleva, K. S., Zubkov, F. I., Bormotov, N. I., Novikov, R. A., Dorovatovskii, P. V., Khrustalev, V. N., Gatilov, Y. V., Zarubaev, V. V., Yarovaya, O. I., Shishkina, L. N. & Salakhutdinov, N. F., 1 Dec 2018, In: MedChemComm. 9, 12, p. 2072-2082 11 p.

    Research output: Contribution to journalArticlepeer-review

  15. Preparation of chiral isobenzofurans from 3-carene in the presence of modified clays

    Sidorenko, A. Y., Il'ina, I. V., Kravtsova, A. V., Aho, A., Ardashov, O. V., Li-Zhulanov, N. S., Volcho, K. P., Salakhutdinov, N. F., Murzin, D. Y. & Agabekov, V. E., 1 Nov 2018, In: Molecular Catalysis. 459, p. 38-45 8 p.

    Research output: Contribution to journalArticlepeer-review

  16. Selection of influenza virus resistant to the novel camphor-based antiviral camphecene results in loss of pathogenicity

    Zarubaev, V. V., Pushkina, E. A., Borisevich, S. S., Galochkina, A. V., Garshinina, A. V., Shtro, A. A., Egorova, A. A., Sokolova, A. S., Khursan, S. L., Yarovaya, O. I. & Salakhutdinov, N. F., 1 Nov 2018, In: Virology. 524, p. 69-77 9 p.

    Research output: Contribution to journalArticlepeer-review

  17. Highly selective reduction of nitroarenes by sc-isopropanol in the presence of zirconia in a flow reactor

    Anikeev, V. I., Sivcev, V. P., Valeev, K. R., Volcho, K. P., Sadykov, V. A. & Salakhutdinov, N. F., 1 Oct 2018, In: Journal of Supercritical Fluids. 140, p. 233-237 5 p.

    Research output: Contribution to journalArticlepeer-review

  18. Synthesis and antiviral activity of camphor-based 1,3-thiazolidin-4-one and thiazole derivatives as Orthopoxvirus-reproduction inhibitors

    Sokolova, A. S., Yarovaya, O. I., Bormotov, N. I., Shishkina, L. N. & Salakhutdinov, N. F., 1 Oct 2018, In: MedChemComm. 9, 10, p. 1746-1753 8 p.

    Research output: Contribution to journalArticlepeer-review

  19. A novel class of tyrosyl-DNA phosphodiesterase 1 inhibitors that contains the octahydro-2H-chromen-4-ol scaffold

    Li-Zhulanov, N. S., Zakharenko, A. L., Chepanova, A. A., Patel, J., Zafar, A., Volcho, K. P., Salakhutdinov, N. F., Reynisson, J., Leung, I. K. H. & Lavrik, O. I., 26 Sept 2018, In: Molecules. 23, 10, 14 p., 2468.

    Research output: Contribution to journalArticlepeer-review

  20. Discovery of a New Class of Inhibitors of Vaccinia Virus Based on (−)-Borneol from Abies sibirica and (+)-Camphor

    Sokolova, A. S., Yarovaya, O. I., Bormotov, N. I., Shishkina, L. N. & Salakhutdinov, N. F., 1 Sept 2018, In: Chemistry and Biodiversity. 15, 9, 9 p., e1800153.

    Research output: Contribution to journalArticlepeer-review

  21. Synthesis and evaluation of aryliden- and hetarylidenfuranone derivatives of usnic acid as highly potent Tdp1 inhibitors

    Zakharova, O., Luzina, O., Zakharenko, A., Sokolov, D., Filimonov, A., Dyrkheeva, N., Chepanova, A., Ilina, E., Ilyina, A., Klabenkova, K., Chelobanov, B., Stetsenko, D., Zafar, A., Eurtivong, C., Reynisson, J., Volcho, K., Salakhutdinov, N. & Lavrik, O., 15 Aug 2018, In: Bioorganic and Medicinal Chemistry. 26, 15, p. 4470-4480 11 p.

    Research output: Contribution to journalArticlepeer-review

  22. Synthesis and evaluation of camphor and cytisine-based cyanopyrrolidines as DPP-IV inhibitors for the treatment of type 2 diabetes mellitus

    Kuranov, S. O., Tsypysheva, I. P., Khvostov, M. V., Zainullina, L. F., Borisevich, S. S., Vakhitova, Y. V., Luzina, O. A. & Salakhutdinov, N. F., 15 Aug 2018, In: Bioorganic and Medicinal Chemistry. 26, 15, p. 4402-4409 8 p.

    Research output: Contribution to journalArticlepeer-review

  23. Preparation of octahydro-2H-chromen-4-ol with analgesic activity from isopulegol and thiophene-2-carbaldehyde in the presence of acid-modified clays

    Sidorenko, A. Y., Kravtsova, A. V., Wärnå, J., Aho, A., Heinmaa, I., Il'ina, I. V., Ardashov, O. V., Volcho, K. P., Salakhutdinov, N. F., Murzin, D. Y. & Agabekov, V. E., 1 Jul 2018, In: Molecular Catalysis. 453, p. 139-148 10 p.

    Research output: Contribution to journalArticlepeer-review

  24. Synthesis and Inhibitory Properties of Imines Containing Monoterpenoid and Adamantane Fragments Against DNA Repair Enzyme Tyrosyl-DNA Phosphodiesterase 1 (Tdp1)

    Zakharenko, A. L., Mozhaitsev, E. S., Suslov, E. V., Korchagina, D. V., Volcho, K. P., Salakhutdinov, N. F. & Lavrik, O. I., 1 Jul 2018, In: Chemistry of Natural Compounds. 54, 4, p. 672-676 5 p.

    Research output: Contribution to journalArticlepeer-review

  25. Highly potent activity of isopulegol-derived substituted octahydro-2H-chromen-4-ols against influenza A and B viruses

    Ilyina, I. V., Zarubaev, V. V., Lavrentieva, I. N., Shtro, A. A., Esaulkova, I. L., Korchagina, D. V., Borisevich, S. S., Volcho, K. P. & Salakhutdinov, N. F., 15 Jun 2018, In: Bioorganic and Medicinal Chemistry Letters. 28, 11, p. 2061-2067 7 p.

    Research output: Contribution to journalArticlepeer-review

  26. Usnic acid and its derivatives for pharmaceutical use: a patent review (2000–2017)

    Luzina, O. A. & Salakhutdinov, N. F., 3 Jun 2018, In: Expert Opinion on Therapeutic Patents. 28, 6, p. 477-491 15 p.

    Research output: Contribution to journalReview articlepeer-review

  27. 3-N-ЗАМЕЩЕННЫЕ БОРНИЛПРОПИОНАТЫ, ИСПОЛЬЗУЕМЫЕ В КАЧЕСТВЕ ИНГИБИТОРОВ ВИРУСА МАРБУРГ

    Яровая, О. И., Соколова, А. С., Кононова, А. А., Чересиз, С. В., Никитина, Р. А., Чепурнов, А. А., Зайковская, А. В., Пьянков, О. В., Покровский, А. Г., Максютов, Р. А. & Салахутдинов, Н. Ф., 3 Apr 2018, IPC No. A61K31/4453, A61K31/452, A61P31/12, C07D211/14, Роспатент - Федеральная служба по интеллектуальной собственности, Patent No. 2649406, Priority date 21 Sept 2017, Priority No. 2017133088

    Research output: PatentPatent for invention

  28. One-pot monoterpene alcohol amination over Au/ZrO2 catalyst: Effect of the substrate structure

    Demidova, Y. S., Suslov, E. V., Simakova, I. L., Mozhajcev, E. S., Korchagina, D. V., Volcho, K. P., Salakhutdinov, N. F., Simakov, A. & Murzin, D. Y., 1 Apr 2018, In: Journal of Catalysis. 360, p. 127-134 8 p.

    Research output: Contribution to journalArticlepeer-review

  29. Novel semisynthetic derivatives of bile acids as effective tyrosyl-DNA phosphodiesterase 1 inhibitors

    Salomatina, O. V., Popadyuk, I. I., Zakharenko, A. L., Zakharova, O. D., Fadeev, D. S., Komarova, N. I., Reynisson, J., Arabshahi, H. J., Chand, R., Volcho, K. P., Salakhutdinov, N. F. & Lavrik, O. I., 17 Mar 2018, In: Molecules. 23, 3, 19 p., 679.

    Research output: Contribution to journalArticlepeer-review

  30. Antiulcerogenic activity of borneol derivatives

    Borisova, M. S., Yarovaya, O. I., Semenova, M. D., Tolstikova, T. G. & Salakhutdinov, N. F., 1 Mar 2018, In: Russian Chemical Bulletin. 67, 3, p. 558-561 4 p.

    Research output: Contribution to journalArticlepeer-review

  31. Development and Validation of a Method for Determination of a New Effective Inhibitor of Influenza Virus H1N1 in Blood Plasma

    Sokolova, A. S., Yarovaya, O. I., Nefedov, A. A. & Salakhutdinov, N. F., Mar 2018, In: Pharmaceutical Chemistry Journal. 51, 12, p. 1102-1105 4 p.

    Research output: Contribution to journalArticlepeer-review

  32. Aminoadamantanes containing monoterpene-derived fragments as potent tyrosyl-DNA phosphodiesterase 1 inhibitors

    Ponomarev, K. Y., Suslov, E. V., Zakharenko, A. L., Zakharova, O. D., Rogachev, A. D., Korchagina, D. V., Zafar, A., Reynisson, J., Nefedov, A. A., Volcho, K. P., Salakhutdinov, N. F. & Lavrik, O. I., 1 Feb 2018, In: Bioorganic Chemistry. 76, p. 392-399 8 p.

    Research output: Contribution to journalArticlepeer-review

  33. Application of monoterpenoids and their derivatives for treatment of neurodegenerative disorders

    Volcho, K. P., Laev, S. S., Ashraf, G. M., Aliev, G. & Salakhutdinov, N. F., 1 Jan 2018, In: Current Medicinal Chemistry. 25, 39, p. 5327-5346 20 p.

    Research output: Contribution to journalReview articlepeer-review

  34. Synthesis of Sulfones and Sulfoxides Based on (+)-usnic Acid

    Sokolov, D. N., Luzina, O. A. & Salakhutdinov, N. F., 1 Jan 2018, In: Chemistry of Natural Compounds. 54, 1, p. 46-49 4 p.

    Research output: Contribution to journalArticlepeer-review

  35. 2017
  36. N-Heterocyclic borneol derivatives as inhibitors of Marburg virus glycoprotein-mediated VSIV pseudotype entry

    Kononova, A. A., Sokolova, A. S., Cheresiz, S. V., Yarovaya, O. I., Nikitina, R. A., Chepurnov, A. A., Pokrovsky, A. G. & Salakhutdinov, N. F., 1 Dec 2017, In: MedChemComm. 8, 12, p. 2233-2237 5 p.

    Research output: Contribution to journalArticlepeer-review

  37. Synthesis and analgesic activity of amines combining diazaadamantane and monoterpene fragments

    Ponomarev, K., Morozova, E., Pavlova, A., Suslov, E., Korchagina, D., Nefedov, A., Tolstikova, T., Volcho, K. & Salakhutdinov, N., 1 Dec 2017, In: Medicinal Chemistry. 13, 8, p. 773-779 7 p.

    Research output: Contribution to journalArticlepeer-review

  38. Evolution of anti-parkinsonian activity of monoterpenoid (1R,2R,6S)-3-methyl-6-(prop-1-en-2-yl)cyclohex-3-ene-1,2-diol in various in vivo models

    Valdman, E., Kapitsa, I., Ivanova, Е., Voronina, T., Ardashov, O., Volcho, K., Khazanov, V. & Salakhutdinov, N., 15 Nov 2017, In: European Journal of Pharmacology. 815, p. 351-363 13 p.

    Research output: Contribution to journalArticlepeer-review

  39. Synthesis and Analgesic Activity of 4,7-Dimethyl-3,4,4a,5,8,8a-Hexahydro-2-Chromen-4,8-Diols Containing Alkyl-Substituted Aromatic Moieties

    Patrusheva, O. S., Pavlova, A. V., Korchagina, D. V., Tolstikova, T. G., Volcho, K. P. & Salakhutdinov, N. F., 1 Nov 2017, In: Chemistry of Natural Compounds. 53, 6, p. 1066-1071 6 p.

    Research output: Contribution to journalArticlepeer-review

  40. Synthesis and Analgesic Activity of 5,7- and 6-Substituted Diazaadamantanes Containing Monoterpene Moieties

    Ponomarev, K. Y., Morozova, E. A., Suslov, E. V., Korchagina, D. V., Tolstikova, T. G., Volcho, K. P. & Salakhutdinov, N. F., 1 Nov 2017, In: Chemistry of Natural Compounds. 53, 6, p. 1131-1136 6 p.

    Research output: Contribution to journalArticlepeer-review

  41. Synthesis and evaluation of antitumor, anti-inflammatory and analgesic activity of novel deoxycholic acid derivatives bearing aryl- or hetarylsulfanyl moieties at the C-3 position

    Popadyuk, I. I., Markov, A. V., Morozova, E. A., Babich, V. O., Salomatina, O. V., Logashenko, E. B., Zenkova, M. A., Tolstikova, T. G. & Salakhutdinov, N. F., Nov 2017, In: Steroids. 127, p. 1-12 12 p.

    Research output: Contribution to journalArticlepeer-review

  42. Anti-influenza activity of diazaadamantanes combined with monoterpene moieties

    Suslov, E., Zarubaev, V. V., Slita, A. V., Ponomarev, K., Korchagina, D., Ayine-Tora, D. M., Reynisson, J., Volcho, K. & Salakhutdinov, N., 1 Oct 2017, In: Bioorganic and Medicinal Chemistry Letters. 27, 19, p. 4531-4535 5 p.

    Research output: Contribution to journalArticlepeer-review

  43. Novel derivatives of deoxycholic acid bearing aliphatic or cyclic diamine moieties at the C-3 position: Synthesis and evaluation of anti-proliferative activity

    Popadyuk, I. I., Markov, A. V., Babich, V. O., Salomatina, O. V., Logashenko, E. B., Zenkova, M. A. & Salakhutdinov, N. F., 15 Aug 2017, In: Bioorganic and Medicinal Chemistry Letters. 27, 16, p. 3755-3759 5 p.

    Research output: Contribution to journalArticlepeer-review

  44. Benzopentathiepine derivative, 8-(Trifluoromethyl)-1,2,3,4,5-benzopentathiepin-6-amine hydrochloride (TC-2153), as a promising antidepressant of new generation

    Kulikova, E. A., Volcho, K. P., Salakhutdinov, N. F. & Kulikov, A. V., 1 Aug 2017, In: Letters in Drug Design and Discovery. 14, 8, p. 974-984 11 p.

    Research output: Contribution to journalReview articlepeer-review

  45. Synthesis and analgesic activity of monoterpenoid-derived alkyl-substituted chiral hexahydro-2H-chromenes

    Il’ina, I., Pavlova, A., Korchagina, D., Ardashov, O., Tolstikova, T., Volcho, K. & Salakhutdinov, N., 1 Jul 2017, In: Medicinal Chemistry Research. 26, 7, p. 1415-1426 12 p.

    Research output: Contribution to journalArticlepeer-review

  46. Synthesis of camphecene derivatives using click chemistry methodology and study of their antiviral activity

    Artyushin, O. I., Sharova, E. V., Vinogradova, N. M., Genkina, G. K., Moiseeva, A. A., Klemenkova, Z. S., Orshanskaya, I. R., Shtro, A. A., Kadyrova, R. A., Zarubaev, V. V., Yarovaya, O. I., Salakhutdinov, N. F. & Brel, V. K., 15 May 2017, In: Bioorganic and Medicinal Chemistry Letters. 27, 10, p. 2181-2184 4 p.

    Research output: Contribution to journalArticlepeer-review

  47. One-pot synthesis of 1,5,3-oxathiazepanes via the three-component condensation of primary amines, formaldehyde and 2-mercaptoethanol

    Kovaleva, K. S., Yarovaya, O. I., Fadeev, D. S. & Salakhutdinov, N. F., 10 May 2017, In: Tetrahedron Letters. 58, 19, p. 1868-1870 3 p.

    Research output: Contribution to journalArticlepeer-review

  48. Inhibitors of nuclease and redox activity of apurinic/apyrimidinic endonuclease 1/redox effector factor 1 (APE1/Ref-1)

    Laev, S. S., Salakhutdinov, N. F. & Lavrik, O. I., 1 May 2017, In: Bioorganic and Medicinal Chemistry. 25, 9, p. 2531-2544 14 p.

    Research output: Contribution to journalReview articlepeer-review

  49. Synthesis and in vitro study of novel borneol derivatives as potent inhibitors of the influenza A virus

    Sokolova, A. S., Yarovaya, O. I., Semenova, M. D., Shtro, A. A., Orshanskaya, I. R., Zarubaev, V. V. & Salakhutdinov, N. F., 1 May 2017, In: MedChemComm. 8, 5, p. 960-963 4 p.

    Research output: Contribution to journalArticlepeer-review

  50. The decisive role of mutual arrangement of hydroxy and methoxy groups in (3(4)-hydroxy-4(3)-methoxyphenyl)-4,7-dimethyl-3,4,4a,5,8,8ahexahydro- 2H-chromene-4,8-diols in their Biological Activity

    Pavlova, A., Patrusheva, O., Il'ina, I., Volcho, K., Tolstikova, T. & Salakhutdinov, N., 1 May 2017, In: Letters in Drug Design and Discovery. 14, 5, p. 508-514 7 p.

    Research output: Contribution to journalArticlepeer-review

  51. Promoting effect of alcohols and formic acid on Au-catalyzed one-pot myrtenol amination

    Demidova, Y. S., Suslov, E. V., Simakova, I. L., Volcho, K. P., Smolentseva, E., Salakhutdinov, N. F., Simakov, A. & Murzin, D. Y., May 2017, In: Molecular Catalysis. 433, p. 414-419 6 p.

    Research output: Contribution to journalArticlepeer-review

  52. Influenza Antiviral Activity of Br-Containing [2R,4R(S),4aR,7R,8aR]-4,7-Dimethyl-2-(Thiophen-2-YL)Octahydro-2H-Chromen-4-Ols Prepared from (–)-Isopulegol

    Nazimova, E. V., Shtro, A. A., Anikin, V. B., Patrusheva, O. S., Il′ina, I. V., Korchagina, D. V., Zarubaev, V. V., Volcho, K. P. & Salakhutdinov, N. F., 1 Mar 2017, In: Chemistry of Natural Compounds. 53, 2, p. 260-264 5 p.

    Research output: Contribution to journalArticlepeer-review

ID: 3454033