A Novel Small Molecule Supports the Survival of Cultured Dopamine Neurons and May Restore the Dopaminergic Innervation of the Brain in the MPTP Mouse Model of Parkinson's Disease

dopamine neurons, ERK pathway, MAPK signaling, neurorestoration, Parkinson’s disease, tyrosine hydroxylase, Parkinson's disease, MANAGEMENT, NEUROTROPHIC FACTOR, PROTEIN-KINASE, RECEPTOR, MAPK signaling ERK pathway, GDNF, ANIMAL-MODELS, SELEGILINE, GFR-ALPHA-1, DERIVATIVES, CYCLOHEX-3-ENE-1,2-DIOL, Cell Survival/drug effects, Corpus Striatum/drug effects, Dopaminergic Neurons/cytology, Motor Activity/drug effects, Tyrosine 3-Monooxygenase/metabolism, Cells, Cultured, Neuroprotective Agents/pharmacology, Signal Transduction/drug effects, Animals, MPTP Poisoning/drug therapy, Mitogen-Activated Protein Kinases/metabolism, Mice

ID: 21857422