A Novel Small Molecule Supports the Survival of Cultured Dopamine Neurons and May Restore the Dopaminergic Innervation of the Brain in the MPTP Mouse Model of Parkinson's Disease

Research output: Contribution to journal › Article › peer-review

dopamine neurons, ERK pathway, MAPK signaling, neurorestoration, Parkinson’s disease, tyrosine hydroxylase, Parkinson's disease, MANAGEMENT, NEUROTROPHIC FACTOR, PROTEIN-KINASE, RECEPTOR, MAPK signaling ERK pathway, GDNF, ANIMAL-MODELS, SELEGILINE, GFR-ALPHA-1, DERIVATIVES, CYCLOHEX-3-ENE-1,2-DIOL, Cell Survival/drug effects, Corpus Striatum/drug effects, Dopaminergic Neurons/cytology, Motor Activity/drug effects, Tyrosine 3-Monooxygenase/metabolism, Cells, Cultured, Neuroprotective Agents/pharmacology, Signal Transduction/drug effects, Animals, MPTP Poisoning/drug therapy, Mitogen-Activated Protein Kinases/metabolism, Mice

ID: 21857422