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  1. 2022

  2. The C-Terminal Domain of Y-Box Binding Protein 1 Exhibits Structure-Specific Binding to Poly(ADP-Ribose), Which Regulates PARP1 Activity

    Naumenko, K. N., Sukhanova, M. V., Hamon, L., Kurgina, T. A., Anarbaev, R. O., Mangerich, A., Pastré, D. & Lavrik, O. I., 21 Jun 2022, In: Frontiers in Cell and Developmental Biology. 10, 831741.

    Research output: Contribution to journal › Article › peer-review

  3. 2021

  4. Dual function of HPF1 in the modulation of PARP1 and PARP2 activities

    Kurgina, T. A., Moor, N. A., Kutuzov, M. M., Naumenko, K. N., Ukraintsev, A. A. & Lavrik, O. I., Dec 2021, In: Communications Biology. 4, 1, 1259.

    Research output: Contribution to journal › Article › peer-review

  5. Dehydroabietylamine-based thiazolidin-4-ones and 2-thioxoimidazolidin-4-ones as novel tyrosyl-DNA phosphodiesterase 1 inhibitors

    Kovaleva, K., Mamontova, E., Yarovaya, O., Zakharova, O., Zakharenko, A., Lavrik, O. & Salakhutdinov, N., Nov 2021, In: Molecular Diversity. 25, 4, p. 2389-2397 9 p.

    Research output: Contribution to journal › Article › peer-review

  6. A Method for Assessing the Efficiency of the Nucleotide Excision Repair System Ex Vivo

    Popov, A. A., Orishchenko, K. E., Naumenko, K. N., Evdokimov, A. N., Petruseva, I. O. & Lavrik, O. I., Sept 2021, In: Acta Naturae. 13, 3, p. 122-125 4 p., 13.

    Research output: Contribution to journal › Article › peer-review

  7. A structural mechanism of DNA polymerase lambda action that promotes error-free bypass of bulky modifications in DNA

    Zhdanova, P., Lomzov, A., Rechkunova, N. & Koval, V., Jul 2021, In: FEBS Open Bio. 11, p. 180-181 2 p.

    Research output: Contribution to journal › Meeting Abstract › peer-review

  8. Impact of various poly(ADP-ribose)polymerase 1 level on DNA base excision repair status in human cells

    Kochetkova, A. S., Ilina, E. S., Khodyreva, S. N. & Lavrik, O. I., Jul 2021, In: FEBS Open Bio. 11, p. 190-190 1 p.

    Research output: Contribution to journal › Meeting Abstract › peer-review

  9. Mechanism of target nucleotide recognition and cleavage in the model non-canonical DNA and RNA structures by human AP-endonuclease APE1

    Davletgildeeva, A., Kuznetsova, A., Fedorova, O. & Kuznetsov, N., Jul 2021, In: FEBS Open Bio. 11, p. 246-246 1 p.

    Research output: Contribution to journal › Meeting Abstract › peer-review

  10. PARP1, PARP2 and PARP3 interaction with nucleosomes containing DNA-lesions

    Kurgina, T. A., Kutuzov, M. M., Belousova, E. A., Ukraitsev, A. A., Anarbaev, R. O. & Lavrik, O. I., Jul 2021, In: FEBS Open Bio. 11, p. 244-245 2 p.

    Research output: Contribution to journal › Meeting Abstract › peer-review

  11. Roles of active-site amino acid residues in RNA cleavage by human AP endonuclease APE1

    Kuznetsova, A., Gavrilova, A., Fedorova, O. & Kuznetsov, N., Jul 2021, In: FEBS Open Bio. 11, p. 246-246 1 p.

    Research output: Contribution to journal › Meeting Abstract › peer-review

  12. Analysis of peptides and small proteins in preparations of horse milk exosomes, purified on anti-CD81-Sepharose

    Sedykh, S. E., Purvinish, L. V., Burkova, E. E., Dmitrenok, P. S., Vlassov, V. V., Ryabchikova, E. I. & Nevinsky, G. A., Jun 2021, In: International Dairy Journal. 117, 104994.

    Research output: Contribution to journal › Article › peer-review

  13. Triazinylamidophosphate Oligonucleotides: Synthesis and Study of Their Interaction with Cells and DNA-Binding Proteins

    Kupryushkin, M. S., Zharkov, T. D., Ilina, E. S., Markov, O. V., Kochetkova, A. S., Akhmetova, M. M., Lomzov, A. A., Pyshnyi, D. V., Lavrik, O. I. & Khodyreva, S. N., May 2021, In: Russian Journal of Bioorganic Chemistry. 47, 3, p. 719-733 15 p.

    Research output: Contribution to journal › Article › peer-review

  14. The Enigma of Substrate Recognition and Catalytic Efficiency of APE1-Like Enzymes

    Davletgildeeva, A. T., Ishchenko, A. A., Saparbaev, M., Fedorova, O. S. & Kuznetsov, N. A., 26 Mar 2021, In: Frontiers in Cell and Developmental Biology. 9, p. 617161 617161.

    Research output: Contribution to journal › Article › peer-review

  15. 5'‑дезоксирибозофатлиазная активность апуриновой/апиримидиновой эндонуклеазы 1

    Ilina, E. S., Lavrik, O. I. & Khodyreva, S. N., 1 Mar 2021, In: Molekuliarnaia biologiia. 55, 2, p. 269-276 8 p.

    Research output: Contribution to journal › Article › peer-review

  16. The contribution of PARP1, PARP2 and poly(ADP-ribosyl)ation to base excision repair in the nucleosomal context

    Kutuzov, M. M., Belousova, E. A., Kurgina, T. A., Ukraintsev, A. A., Vasil’eva, I. A., Khodyreva, S. N. & Lavrik, O. I., 1 Mar 2021, In: Scientific Reports. 11, 1, 4849.

    Research output: Contribution to journal › Article › peer-review

  17. Интерактом систем репарации оснований и нуклеотидов

    Rechkunova, N. I., Krasikova, Y. S. & Lavrik, O. I., 1 Mar 2021, In: Molekuliarnaia biologiia. 55, 2, p. 181-193 13 p., 2.

    Research output: Contribution to journal › Review article › peer-review

  18. Мутационный и кинетический анализ эндорибонуклеазной активности АРЕ1

    Kuznetsova, A. A., Gavrilova, A. A., Novopashina, D. S., Fedorova, O. S. & Kuznetsov, N. A., 1 Mar 2021, In: Molekuliarnaia biologiia. 55, 2, p. 243-257 15 p., 6.

    Research output: Contribution to journal › Article › peer-review

  19. Противоопухлевая активность комбинации топотекана и ингибитора тирозил-ДНК-фосфодиэстеразы 1 на модели асцитной карциномы Кребс-2 мыши

    Dyrkheeva, N. S., Zakharenko, A. L., Novoselova, E. S., Chepanova, A. A., Popova, N. A., Nikolin, V. P., Luzina, O. A., Salakhutdinov, N. F., Ryabchikova, E. I. & Lavrik, O. I., 1 Mar 2021, In: Molekuliarnaia biologiia. 55, 2, p. 312-317 6 p., 12.

    Research output: Contribution to journal › Article › peer-review

  20. Сравнительный анализ активности полиморфных вариантов урацил-ДНК-гликолиаз человека человека SMUG1 и MBD4

    Alekseeva, I. V., Bakman, A. S., Iakovlev, D. A., Kuznetsov, N. A. & Fedorova, O. S., 1 Mar 2021, In: Molekuliarnaia biologiia. 55, 2, p. 277-288 12 p., 9.

    Research output: Contribution to journal › Article › peer-review

  21. 5'-Deoxyribose Phosphate Lyase Activity of Apurinic/Apyrimidinic Endonuclease 1

    Ilina, E. S., Lavrik, O. I. & Khodyreva, S. N., Mar 2021, In: Molecular Biology. 55, 2, p. 234-240 7 p.

    Research output: Contribution to journal › Article › peer-review

  22. Antitumor Activity of the Combination of Topotecan and Tyrosyl-DNA-Phosphodiesterase 1 Inhibitor on Model Krebs-2 Mouse Ascite Carcinoma

    Dyrkheeva, N. S., Zakharenko, A. L., Novoselova, E. S., Chepanova, A. A., Popova, N. A., Nikolin, V. P., Luzina, O. A., Salakhutdinov, N. F., Ryabchikova, E. I. & Lavrik, O. I., Mar 2021, In: Molecular Biology. 55, 2, p. 273-277 5 p.

    Research output: Contribution to journal › Article › peer-review

  23. Comparative Analysis of the Activity of the Polymorphic Variants of Human Uracil-DNA-Glycosylases SMUG1 and MBD4

    Alekseeva, I., Bakman, A. S., Iakovlev, D. A., Kuznetsov, N. A. & Fedorova, O. S., Mar 2021, In: Molecular Biology. 55, 2, p. 241-251 11 p.

    Research output: Contribution to journal › Article › peer-review

  24. Interactome of Base and Nucleotide Excision DNA Repair Systems

    Rechkunova, N. I., Krasikova, Y. S. & Lavrik, O. I., Mar 2021, In: Molecular Biology. 55, 2, p. 155-166 12 p.

    Research output: Contribution to journal › Review article › peer-review

  25. Human placenta exosomes: Biogenesis, isolation, composition, and prospects for use in diagnostics

    Burkova, E. E., Sedykh, S. E. & Nevinsky, G. A., 2 Feb 2021, In: International Journal of Molecular Sciences. 22, 4, p. 1-20 20 p., 2158.

    Research output: Contribution to journal › Review article › peer-review

  26. Apurinic/Apyrimidinic Endonuclease 1 and Tyrosyl-DNA Phosphodiesterase 1 Prevent Suicidal Covalent DNA-Protein Crosslink at Apurinic/Apyrimidinic Site

    Lebedeva, N. A., Rechkunova, N. I., Endutkin, A. V. & Lavrik, O. I., 11 Jan 2021, In: Frontiers in Cell and Developmental Biology. 8, 8 p., 617301.

    Research output: Contribution to journal › Article › peer-review

  27. 2020

  28. Human Tyrosyl-DNA Phosphodiesterase 1 Possesses Transphosphooligonucleotidation Activity With Primary Alcohols

    Dyrkheeva, N., Anarbaev, R., Lebedeva, N., Kuprushkin, M., Kuznetsova, A., Kuznetsov, N., Rechkunova, N. & Lavrik, O., 23 Dec 2020, In: Frontiers in Cell and Developmental Biology. 8, 12 p., 604732.

    Research output: Contribution to journal › Article › peer-review

  29. The role of active-site amino acid residues in the cleavage of DNA and RNA substrates by human apurinic/apyrimidinic endonuclease APE1

    Alekseeva, I. V., Kuznetsova, A. A., Bakman, A. S., Fedorova, O. S. & Kuznetsov, N. A., 1 Dec 2020, In: Biochimica et Biophysica Acta - General Subjects. 1864, 12, 13 p., 129718.

    Research output: Contribution to journal › Article › peer-review

  30. Lesion Recognition and Cleavage of Damage-Containing Quadruplexes and Bulged Structures by DNA Glycosylases

    Kuznetsova, A. A., Fedorova, O. S. & Kuznetsov, N. A., 30 Nov 2020, In: Frontiers in Cell and Developmental Biology. 8, 16 p., 595687.

    Research output: Contribution to journal › Article › peer-review

  31. Activity of Human Apurinic/Apyrimidinic Endonuclease APE1 Toward Damaged DNA and Native RNA With Non-canonical Structures

    Davletgildeeva, A. T., Kuznetsova, A. A., Fedorova, O. S. & Kuznetsov, N. A., 30 Oct 2020, In: Frontiers in Cell and Developmental Biology. 8, 14 p., 590848.

    Research output: Contribution to journal › Article › peer-review

  32. Modulation of the apurinic/apyrimidinic endonuclease activity of human APE1 and of its natural polymorphic variants by base excision repair proteins

    Kladova, O. A., Alekseeva, I. V., Saparbaev, M., Fedorova, O. S. & Kuznetsov, N. A., 1 Oct 2020, In: International Journal of Molecular Sciences. 21, 19, p. 1-15 15 p., 7147.

    Research output: Contribution to journal › Article › peer-review

  33. The first berberine-based inhibitors of tyrosyl-dna phosphodiesterase 1 (Tdp1), an important dna repair enzyme

    Gladkova, E. D., Nechepurenko, I. V., Bredikhin, R. A., Chepanova, A. A., Zakharenko, A. L., Luzina, O. A., Ilina, E. S., Dyrkheeva, N. S., Mamontova, E. M., Anarbaev, R. O., Reynisson, J., Volcho, K. P., Salakhutdinov, N. F. & Lavrik, O. I., 1 Oct 2020, In: International Journal of Molecular Sciences. 21, 19, p. 1-16 16 p., 7162.

    Research output: Contribution to journal › Article › peer-review

  34. Natural catalytic IgGs hydrolyzing histones in schizophrenia: Are they the link between humoral immunity and inflammation?

    Ermakov, E. A., Parshukova, D. A., Nevinsky, G. A. & Buneva, V. N., 30 Sept 2020, In: International Journal of Molecular Sciences. 21, 19, p. 1-25 25 p., 7238.

    Research output: Contribution to journal › Article › peer-review

  35. Regulation of poly(ADP-Ribose) polymerase 1 activity by Y-Box-binding protein 1

    Naumenko, K. N., Sukhanova, M. V., Hamon, L., Kurgina, T. A., Alemasova, E. E., Kutuzov, M. M., Pastré, D. & Lavrik, O. I., 16 Sept 2020, In: Biomolecules. 10, 9, p. 1-26 26 p., 1325.

    Research output: Contribution to journal › Article › peer-review

  36. Milk exosomes: Perspective agents for anticancer drug delivery

    Sedykh, S., Kuleshova, A. & Nevinsky, G., 11 Sept 2020, In: International Journal of Molecular Sciences. 21, 18, p. 1-16 16 p., 6646.

    Research output: Contribution to journal › Review article › peer-review

  37. The Role of Active-Site Plasticity in Damaged-Nucleotide Recognition by Human Apurinic/Apyrimidinic Endonuclease APE1

    Bulygin, A. A., Kuznetsova, A. A., Vorobjev, Y. N., Fedorova, O. S. & Kuznetsov, N. A., 1 Sept 2020, In: Molecules. 25, 17, 13 p., 3940.

    Research output: Contribution to journal › Article › peer-review

  38. PARPs’ impact on base excision DNA repair

    Lavrik, O. I., Sept 2020, In: DNA Repair. 93, 6 p., 102911.

    Research output: Contribution to journal › Review article › peer-review

  39. Usnic Acid Conjugates with Monoterpenoids as Potent Tyrosyl-DNA Phosphodiesterase 1 Inhibitors

    Luzina, O., Filimonov, A., Zakharenko, A., Chepanova, A., Zakharova, O., Ilina, E., Dyrkheeva, N., Likhatskaya, G., Salakhutdinov, N. & Lavrik, O., 28 Aug 2020, In: Journal of Natural Products. 83, 8, p. 2320-2329 10 p.

    Research output: Contribution to journal › Article › peer-review

  40. Inhibition of tyrosyl-DNA phosphodiesterase 1 by lipophilic pyrimidine nucleosides

    Zakharenko, A. L., Drenichev, M. S., Dyrkheeva, N. S., Ivanov, G. A., Oslovsky, V. E., Ilina, E. S., Chernyshova, I. A., Lavrik, O. I. & Mikhailov, S. N., 13 Aug 2020, In: Molecules. 25, 16, 13 p., 3694.

    Research output: Contribution to journal › Article › peer-review

  41. Immunoglobulins with non-canonical functions in inflammatory and autoimmune disease states

    Ermakov, E. A., Nevinsky, G. A. & Buneva, V. N., 1 Aug 2020, In: International Journal of Molecular Sciences. 21, 15, p. 1-34 34 p., 5392.

    Research output: Contribution to journal › Review article › peer-review

  42. Design, Synthesis, and Biological Investigation of Novel Classes of 3-Carene-Derived Potent Inhibitors of TDP1

    Il'ina, I. V., Dyrkheeva, N. S., Zakharenko, A. L., Sidorenko, A. Y., Li-Zhulanov, N. S., Korchagina, D. V., Chand, R., Ayine-Tora, D. M., Chepanova, A. A., Zakharova, O. D., Ilina, E. S., Reynisson, J., Malakhova, A. A., Medvedev, S. P., Zakian, S. M., Volcho, K. P., Salakhutdinov, N. F. & Lavrik, O. I., Aug 2020, In: Molecules (Basel, Switzerland). 25, 15, 22 p., 3496.

    Research output: Contribution to journal › Article › peer-review

  43. Characterization of the Altai Maral Chymosin Gene, Production of a Chymosin Recombinant Analog in the Prokaryotic Expression System, and Analysis of Its Several Biochemical Properties

    Belenkaya, S. V., Bondar, A. A., Kurgina, T. A., Elchaninov, V. V., Bakulina, A. Y., Rukhlova, E. A., Lavrik, O. I., Ilyichev, A. A. & Shcherbakov, D. N., 1 Jul 2020, In: Biochemistry (Moscow). 85, 7, p. 781-791 11 p.

    Research output: Contribution to journal › Article › peer-review

  44. 1,1’-(Гексан-1,6-диил)бис(3-(((1R,4aS,10aR)-7-изопропил-1,4a-диметил-1,2,3,4,4a,9,10,10a-октагидрофенантрен-1-ил)метил)мочевина, проявляющая ингибирующее действие в отношении фермента тирозил-ДНК-фосфодиэстеразы 1 человека и увеличивающая активность темозоломида в отношении клеток глиобластомы

    Ковалева, К. С., Олешко, О. С., Яровая, О. И., Мамонтова, Е. М., Захаренко, А. Л., Захарова, О. Д., Чересиз, С. В., Покровский, А. Г., Лаврик, О. И. & Салахутдинов, Н. Ф., 26 Jun 2020, IPC No. C07C275/24, A61K31/17, A61P35/00, Роспатент - Федеральная служба по интеллектуальной собственности, Patent No. 2724882, Priority date 28 Nov 2019, Priority No. 2019138671

    Research output: Patent › Patent for invention

  45. Non-canonical interaction of DNA repair proteins with intact and cleaved AP sites

    Khodyreva, S. & Lavrik, O., 1 Jun 2020, In: DNA Repair. 90, 15 p., 102847.

    Research output: Contribution to journal › Review article › peer-review

  46. Impact of PARP1, PARP2 & PARP3 on the Base Excision Repair of Nucleosomal DNA

    Kutuzov, M. M., Belousova, E. A., Ilina, E. S. & Lavrik, O. I., 8 May 2020, Mechanisms of Genome Protection and Repair. Zharkov, D. O. (ed.). Springer, Cham, Vol. 1241. p. 47-57 11 p. (Advances in experimental medicine and biology).

    Research output: Chapter in Book/Report/Conference proceeding › Chapter › Research › peer-review

  47. Role of Arg243 and His239 Residues in the Recognition of Damaged Nucleotides by Human Uracil-DNA Glycosylase SMUG1

    Iakovlev, D. A., Alekseeva, I. V., Kuznetsov, N. A. & Fedorova, O. S., 1 May 2020, In: Biochemistry (Moscow). 85, 5, p. 594-603 10 p.

    Research output: Contribution to journal › Article › peer-review

  48. Functional role of N-terminal extension of human ap endonuclease 1 in coordination of base excision dna repair via protein–protein interactions

    Moor, N., Vasil’eva, I. & Lavrik, O., 28 Apr 2020, In: International Journal of Molecular Sciences. 21, 9, 18 p., 3122.

    Research output: Contribution to journal › Article › peer-review

  49. An Assay for the Activity of Base Excision Repair Enzymes in Cellular Extracts Using Fluorescent DNA Probes

    Kladova, O. A., Iakovlev, D. A., Groisman, R., Ishchenko, A. A., Saparbaev, M. K., Fedorova, O. S. & Kuznetsov, N. A., 1 Apr 2020, In: Biochemistry (Moscow). 85, 4, p. 480-489 10 p.

    Research output: Contribution to journal › Article › peer-review

  50. Effect of Human XRCC1 Protein Oxidation on the Functional Activity of Its Complexes with the Key Enzymes of DNA Base Excision Repair

    Vasil’eva, I. A., Moor, N. A. & Lavrik, O. I., 22 Mar 2020, In: Biochemistry (Moscow). 85, 3, p. 288-299 12 p.

    Research output: Contribution to journal › Article › peer-review

  51. Design of an Efficient Inhibitor for the Influenza A Virus M2 Ion Channel

    Vorobjev, Y. N., 1 Mar 2020, In: Molecular Biology. 54, 2, p. 281-291 11 p.

    Research output: Contribution to journal › Article › peer-review

  52. Photoreactive DNA as a Tool to Study Replication Protein A Functioning in DNA Replication and Repair

    Rechkunova, N. I. & Lavrik, O. I., 1 Mar 2020, In: Photochemistry and Photobiology. 96, 2, p. 440-449 10 p.

    Research output: Contribution to journal › Review article › peer-review

  53. Конструирование эффективного ингибитора ионного канала белка М2 вируса гриппа A

    Vorobjev, Y. N., 1 Mar 2020, In: Molekuliarnaia biologiia. 54, 2, p. 321-332 12 p.

    Research output: Contribution to journal › Article › peer-review

  54. Molecular mechanisms of PARP-1 inhibitor 7-methylguanine

    Nilov, D., Maluchenko, N., Kurgina, T., Pushkarev, S., Lys, A., Kutuzov, M., Gerasimova, N., Feofanov, A., Švedas, V., Lavrik, O. & Studitsky, V. M., Mar 2020, In: International Journal of Molecular Sciences. 21, 6, 11 p., 2159.

    Research output: Contribution to journal › Article › peer-review

  55. Identification of novel inhibitors for the tyrosyl-DNA-phosphodiesterase 1 (Tdp1) mutant SCAN1 using virtual screening

    Mamontova, E. M., Zakharenko, A. L., Zakharova, O. D., Dyrkheeva, N. S., Volcho, K. P., Reynisson, J., Arabshahi, H. J., Salakhutdinov, N. F. & Lavrik, O. I., 1 Jan 2020, In: Bioorganic and Medicinal Chemistry. 28, 1, 11 p., 115234.

    Research output: Contribution to journal › Article › peer-review

  56. Promising new inhibitors of tyrosyl-DNA phosphodiesterase I (Tdp 1) combining 4- arylcoumarin and monoterpenoid moieties as components of complex antitumor therapy

    Khomenko, T. M., Zakharenko, A. L., Chepanova, A. A., Ilina, E. S., Zakharova, O. D., Kaledin, V. I., Nikolin, V. P., Popova, N. A., Korchagina, D. V., Reynisson, J., Chand, R., Ayine-tora, D. M., Patel, J., Leung, I. K. H., Volcho, K. P., Salakhutdinov, N. F. & Lavrik, O. I., 1 Jan 2020, In: International Journal of Molecular Sciences. 21, 1, 21 p., 126.

    Research output: Contribution to journal › Article › peer-review

  57. Production of abzymes in th, cba, and c57bl/6 mice before and after mog treatment: Comparing changes in cell differentiation and proliferation

    Aulova, K. S., Urusov, A. E., Toporkova, L. B., Sedykh, S. E., Shevchenko, Y. A., Tereshchenko, V. P., Sennikov, S. V., Budde, T., Meuth, S. G., Popova, N. A., Orlovskaya, I. A. & Nevinsky, G. A., Jan 2020, In: Biomolecules. 10, 1, 24 p., 53.

    Research output: Contribution to journal › Article › peer-review

  58. Chapter 11: Alternative DNA Repair Pathways to Handle Complex DNA Damage Generated by Oxidative Stress and Anticancer Drugs: Alternative DNA Repair Pathways to Handle Complex DNA Damage Generated by Oxidative Stress and Anticancer Drugs

    Федорова, О. С. & Кузнецов, Н. А., 2020, DNA Damage, DNA Repair and Disease: Volume 1. Dizdaroglu, M. & Lloyd, R. S. (eds.). London: Royal Society of Chemistry, Vol. 1. p. 249-278 30 p.

    Research output: Chapter in Book/Report/Conference proceeding › Chapter › Research › peer-review

  59. IgGs-abzymes from the sera of patients with systemic lupus erythematosus hydrolyzed miRNAs

    Ermakov, E. A., Kabirova, E. M., Sizikov, A. E., Buneva, V. N. & Nevinsky, G. A., 2020, In: Journal of Inflammation Research. 13, p. 681-699 19 p.

    Research output: Contribution to journal › Article › peer-review

  60. Naked mole rat cells display more efficient DNA excision repair and higher resistance to toxic impacts than mouse cells

    Evdokimov, A., Petruseva, I., Popov, A., Koval, O. & Lavrik, O., 2020, INTERNATIONAL CONFERENCE LONGEVITY INTERVENTIONS 2020 (ICLI 2020). Kovtun, O. & Bazarnyi (eds.). University of Lueneburg, Department of Economics and Social Sciences, Research Institute on Professions, 6 p. 01017. (BIO Web of Conferences; vol. 22).

    Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Research › peer-review

  61. Определение сравнительной активности ключевых ферментов эксцизионной репарации оснований в клеточных экстрактах

    Кладова, О. А., Яковлев, Д. А., Groisman, R., Ishchenko, A. A., Saparbaev, M. K., Федорова, О. С. & Кузнецов, Н. А., 2020, In: Биохимия. 85, 4, p. 556-566 11 p., 8.

    Research output: Contribution to journal › Article › peer-review

  62. Роль аминокислотных остатков Arg243 и His239 в процессе узнавания поврежденного нуклеотида урацил-ДНК-гликозилазой человека SMUG1

    Яковлев, Д. А., Алексеева, И. В., Кузнецов, Н. А. & Федорова, О. С., 2020, In: Биохимия. 85, 5, p. 695-705 11 p., 8.

    Research output: Contribution to journal › Article › peer-review

  63. Экзосомы молока лошади: выделение, микроскопический и биохимический анализ, перспективы использования

    SEDYKH, S. E., KULESHOVA, A. E., PURVINSH, L. V., BURKOVA, E. E., GRIGORIEVA, A. E., EVTUSHENKO, E. G., STEPANOV, G. A., RYABCHIKOVA, E. I. & NEVINSKII, G. A., 2020, In: Biotekhnologiya. 36, 5, p. 62-71 10 p.

    Research output: Contribution to journal › Article › peer-review

  64. 2019

  65. Substrate specificity of IgGs with peroxidase and oxidoreductase activities from sera of patients with systemic lupus erythematosus and multiple sclerosis

    Tolmacheva, A. S., Buneva, V. N. & Nevinsky, G. A., 1 Dec 2019, In: Journal of Molecular Recognition. 32, 12, p. e2807 15 p., 2807.

    Research output: Contribution to journal › Article › peer-review

  66. Role of Ionizing Amino Acid Residues in the Process of DNA Binding by Human AP Endonuclease 1 and in Its Catalysis

    Alekseeva, I. V., Bakman, A. S., Vorobjev, Y. N., Fedorova, O. S. & Kuznetsov, N. A., 14 Nov 2019, In: Journal of Physical Chemistry B. 123, 45, p. 9546-9556 11 p.

    Research output: Contribution to journal › Article › peer-review

  67. Comparative Analysis of Nucleotide Fluorescent Analogs for Registration of DNA Conformational Changes Induced by Interaction with Formamidopyrimidine-DNA Glycosylase Fpg

    Kuznetsova, A. A., Kladova, O. A., Barthes, N. P. F., Michel, B. Y., Burger, A., Fedorova, O. S. & Kuznetsov, N. A., 1 Nov 2019, In: Russian Journal of Bioorganic Chemistry. 45, 6, p. 591-598 8 p.

    Research output: Contribution to journal › Article › peer-review

  68. Conformational Dynamics of Dioxygenase AlkB and DNA in the Course of Catalytically Active Enzyme–Substrate Complex Formation

    Kanazhevskaya, L. Y., Smyshlyaev, D. A., Alekseeva, I. V. & Fedorova, O. S., 1 Nov 2019, In: Russian Journal of Bioorganic Chemistry. 45, 6, p. 630-640 11 p.

    Research output: Contribution to journal › Article › peer-review

  69. Effective Inhibitors of Tyrosyl-DNA Phosphodiesterase 1 Based on Monoterpenoids as Potential Agents for Antitumor Therapy

    Chepanova, A. A., Li-Zhulanov, N. S., Sukhikh, A. S., Zafar, A., Reynisson, J., Zakharenko, A. L., Zakharova, O. D., Korchagina, D. V., Volcho, K. P., Salakhutdinov, N. F. & Lavrik, O. I., 1 Nov 2019, In: Russian Journal of Bioorganic Chemistry. 45, 6, p. 647-655 9 p.

    Research output: Contribution to journal › Article › peer-review

  70. New Fluorescent Analogs of Nucleotides Based on 3-Hydroxychromone for Recording Conformational Changes of DNA

    Kladova, O. A., Kuznetsova, A. A., Barthes, N. P. F., Michel, B. Y., Burger, A., Fedorova, O. S. & Kuznetsov, N. A., 1 Nov 2019, In: Russian Journal of Bioorganic Chemistry. 45, 6, p. 599-607 9 p.

    Research output: Contribution to journal › Article › peer-review

  71. New hydrazinothiazole derivatives of usnic acid as potent TDP1 inhibitors

    Filimonov, A. S., Chepanova, A. A., Luzina, O. A., Zakharenko, A. L., Zakharova, O. D., Ilina, E. S., Dyrkheeva, N. S., Kuprushkin, M. S., Kolotaev, A. V., Khachatryan, D. S., Patel, J., Leung, I. K. H., Chand, R., Ayine-Tora, D. M., Reynisson, J., Volcho, K. P., Salakhutdinov, N. F. & Lavrik, O. I., 15 Oct 2019, In: Molecules. 24, 20, 3711.

    Research output: Contribution to journal › Article › peer-review

  72. Double-Stranded DNA Fragments Bearing Unrepairable Lesions and Their Internalization into Mouse Krebs-2 Carcinoma Cells

    Dolgova, E. V., Evdokimov, A. N., Proskurina, A. S., Efremov, Y. R., Bayborodin, S. I., Potter, E. A., Popov, A. A., Petruseva, I. O., Lavrik, O. I. & Bogachev, S. S., 1 Oct 2019, In: Nucleic Acid Therapeutics. 29, 5, p. 278-290 13 p.

    Research output: Contribution to journal › Article › peer-review

  73. Evaluation of antioxidant activity and cytotoxicity of polyfluorinated diarylacetylenes and indoles toward human cancer cells

    Zakharova, O., Nevinsky, G., Politanskaya, L., Baev, D., Ovchinnikova, L. & Tretyakov, E., 1 Oct 2019, In: Journal of Fluorine Chemistry. 226, 12 p., 109353.

    Research output: Contribution to journal › Article › peer-review

  74. Dehydroabietylamine Ureas and Thioureas as Tyrosyl-DNA Phosphodiesterase 1 Inhibitors That Enhance the Antitumor Effect of Temozolomide on Glioblastoma Cells

    Kovaleva, K., Oleshko, O., Mamontova, E., Yarovaya, O., Zakharova, O., Zakharenko, A., Kononova, A., Dyrkheeva, N., Cheresiz, S., Pokrovsky, A., Lavrik, O. & Salakhutdinov, N., 27 Sept 2019, In: Journal of Natural Products. 82, 9, p. 2443-2450 8 p.

    Research output: Contribution to journal › Article › peer-review

  75. DNA complexes with human apurinic/apyrimidinic endonuclease 1: structural insights revealed by pulsed dipolar EPR with orthogonal spin labeling

    Krumkacheva, O. A., Shevelev, G. Y., Lomzov, A. A., Dyrkheeva, N. S., Kuzhelev, A. A., Koval, V. V., Tormyshev, V. M., Polienko, Y. F., Fedin, M. V., Pyshnyi, D. V., Lavrik, O. I. & Bagryanskaya, E. G., 5 Sept 2019, In: Nucleic Acids Research. 47, 15, p. 7767-7780 14 p.

    Research output: Contribution to journal › Article › peer-review

  76. Post-translational Modifications of Nucleotide Excision Repair Proteins and Their Role in the DNA Repair

    Rechkunova, N. I., Maltseva, E. A. & Lavrik, O. I., 1 Sept 2019, In: Biochemistry (Moscow). 84, 9, p. 1008-1020 13 p.

    Research output: Contribution to journal › Review article › peer-review

  77. The role of active-site residues Phe98, HiS239, and Arg243 in DNA binding and in the catalysis of human uracil–DNA glycosylase SMUG1

    Iakovlev, D. A., Alekseeva, I. V., Vorobjev, Y. N., Kuznetsov, N. A. & Fedorova, O. S., 28 Aug 2019, In: Molecules. 24, 17, 12 p., 3133.

    Research output: Contribution to journal › Article › peer-review

  78. 1-Адамантил-3-(((1R,4aS,10aR)-7-изопропил-1,4а-диметил-1,2,3,4,4а,9,10,10а-октагидрофенантрен-1-ил)метил)мочевина, проявляющая ингибирующее действие в отношении фермента тирозил-ДНК-фосфодиэстеразы 1 человека и увеличивающая активность темозоломида в отношении клеток глиобластомы

    Олешко, О. С., Ковалева, К. С., Яровая, О. И., Мамонтова, Е. М., Захаренко, А. Л., Захарова, О. Д., Чересиз, С. В., Покровский, А. Г., Лаврик, О. И. & Салахутдинов, Н. Ф., 14 Aug 2019, IPC No. C07C275/22, C07C275/24, A61K31/17, A61P35/00, Роспатент - Федеральная служба по интеллектуальной собственности, Patent No. 2697409, Priority date 30 Apr 2019, Priority No. 2019113591

    Research output: Patent › Patent for invention

  79. The impact of single-nucleotide polymorphisms of human apurinic/apyrimidinic endonuclease 1 on specific DNA binding and catalysis

    Alekseeva, I. V., Davletgildeeva, A. T., Arkova, O. V., Kuznetsov, N. A. & Fedorova, O. S., 1 Aug 2019, In: Biochimie. 163, p. 73-83 11 p.

    Research output: Contribution to journal › Article › peer-review

  80. A fresh look at the structural diversity of dibenzoylmethanide complexes of lanthanides

    Sukhikh, T. S., Kolybalov, D. S., Pylova, E. K., Bashirov, D. A., Komarov, V. Y., Kuratieva, N. V., Smolentsev, A. I., Fitch, A. N. & Konchenko, S. N., 7 Jul 2019, In: New Journal of Chemistry. 43, 25, p. 9934-9942 9 p.

    Research output: Contribution to journal › Article › peer-review

  81. Dual DNA topoisomerase 1 and tyrosyl-DNA phosphodiesterase 1 inhibition for improved anticancer activity

    Zakharenko, A., Dyrkheeva, N. & Lavrik, O., 1 Jul 2019, In: Medicinal Research Reviews. 39, 4, p. 1427-1441 15 p.

    Research output: Contribution to journal › Review article › peer-review

  82. The development of Tyrosyl-DNA phosphodiesterase 1 inhibitors. Combination of Monoterpene and Adamantine Moieties via Amide or Thioamide Bridges

    Chepanova, A. A., Mozhaitsev, E. S., Munkuev, A. A., Suslov, E. V., Korchagina, D. V., Zakharova, O. D., Zakharenko, A. L., Patel, J., Ayine-Tora, D. M., Reynisson, J., Leung, I. K. H., Volcho, K. P., Salakhutdinov, N. F. & Lavrik, O. I., 1 Jul 2019, In: Applied Sciences (Switzerland). 9, 13, 2767.

    Research output: Contribution to journal › Article › peer-review

  83. Analysis of proteins and peptides of milk exosomes

    Purvinsh, L., Sedykh, S. & Nevinsky, G., Jul 2019, In: FEBS Open Bio. 9, p. 404-404 1 p.

    Research output: Contribution to journal › Meeting Abstract › peer-review

  84. Human placenta exosomes: isolation, proteins and nucleic acids

    Burkova, E. E., Kompaneets, I. Y. & Nevinsky, G. A., Jul 2019, In: FEBS Open Bio. 9, p. 404-404 1 p.

    Research output: Contribution to journal › Meeting Abstract › peer-review

  85. MicroRNA content in human milk exosomes: isolation, detection, normalization

    Sedykh, S., Purvinsh, L. & Nevinsky, G., Jul 2019, In: FEBS Open Bio. 9, p. 245-245 1 p.

    Research output: Contribution to journal › Meeting Abstract › peer-review

  86. Roles of Active-Site Amino Acid Residues in Specific Recognition of DNA Lesions by Human 8-Oxoguanine-DNA Glycosylase (OGG1)

    Tyugashev, T. E., Vorobjev, Y. N., Kuznetsova, A. A., Lukina, M. V., Kuznetsov, N. A. & Fedorova, O. S., 13 Jun 2019, In: Journal of Physical Chemistry B. 123, 23, p. 4878-4887 10 p.

    Research output: Contribution to journal › Article › peer-review

  87. Poly(ADP-ribosyl)ation and DNA repair synthesis in the extracts of naked mole rat, mouse, and human cells

    Kosova, A. A., Kutuzov, M. M., Evdokimov, A. N., Ilina, E. S., Belousova, E. A., Romanenko, S. A., Trifonov, V. A., Khodyreva, S. N. & Lavrik, O. I., 15 May 2019, In: Aging. 11, 9, p. 2852-2873 22 p.

    Research output: Contribution to journal › Article › peer-review

  88. PARP-1 Activation Directs FUS to DNA Damage Sites to Form PARG-Reversible Compartments Enriched in Damaged DNA

    Singatulina, A. S., Hamon, L., Sukhanova, M. V., Desforges, B., Joshi, V., Bouhss, A., Lavrik, O. I. & Pastré, D., 7 May 2019, In: Cell Reports. 27, 6, p. 1809-1821.e5 18 p.

    Research output: Contribution to journal › Article › peer-review

  89. Poly(ADP-ribosyl)ation by PARP1: reaction mechanism and regulatory proteins

    Alemasova, E. E. & Lavrik, O. I., 7 May 2019, In: Nucleic Acids Research. 47, 8, p. 3811-3827 17 p.

    Research output: Contribution to journal › Article › peer-review

  90. Antimetastatic Activity of Combined Topotecan and Tyrosyl-DNA Phosphodiesterase-1 Inhibitor on Modeled Lewis Lung Carcinoma

    Koldysheva, E. V., Men’shchikova, A. P., Lushnikova, E. L., Popova, N. A., Kaledin, V. I., Nikolin, V. P., Zakharenko, A. L., Luzina, O. A., Salakhutdinov, N. F. & Lavrik, O. I., 15 Mar 2019, In: Bulletin of Experimental Biology and Medicine. 166, 5, p. 661-666 6 p.

    Research output: Contribution to journal › Article › peer-review

  91. Conformational Dynamics of Damage Processing by Human DNA Glycosylase NEIL1

    Kladova, O. A., Grin, I. R., Fedorova, O. S., Kuznetsov, N. A. & Zharkov, D. O., 15 Mar 2019, In: Journal of Molecular Biology. 431, 6, p. 1098-1112 15 p.

    Research output: Contribution to journal › Article › peer-review

  92. Dynamic light scattering study of base excision DNA repair proteins and their complexes

    Vasil'eva, I. A., Anarbaev, R. O., Moor, N. A. & Lavrik, O. I., 1 Mar 2019, In: Biochimica et Biophysica Acta - Proteins and Proteomics. 1867, 3, p. 297-305 9 p.

    Research output: Contribution to journal › Article › peer-review

  93. Autoimmunity and immune system dysregulation in schizophrenia: IgGs from sera of patients hydrolyze myelin basic protein

    Parshukova, D., Smirnova, L. P., Ermakov, E. A., Bokhan, N. A., Semke, A. V., Ivanova, S. A., Buneva, V. N. & Nevinsky, G. A., 1 Feb 2019, In: Journal of Molecular Recognition. 32, 2, 13 p., e2759.

    Research output: Contribution to journal › Article › peer-review

  94. Optimization of nucleosome assembling from histones and model DNAs and estimation of the reconstitution efficiency

    Kutuzov, M. M., Kurgina, T. A., Belousova, E. A., Khodyreva, S. N. & Lavrik, O. I., 1 Feb 2019, In: Biopolymers and Cell. 35, 2, p. 91-98 8 p.

    Research output: Contribution to journal › Article › peer-review

  95. Inhibitory Effect of New Semisynthetic Usnic Acid Derivatives on Human Tyrosyl-DNA Phosphodiesterase 1

    Dyrkheeva, N., Luzina, O., Filimonov, A., Zakharova, O., Ilina, E., Zakharenko, A., Kuprushkin, M., Nilov, D., Gushchina, I., Švedas, V., Salakhutdinov, N. & Lavrik, O., 1 Jan 2019, In: Planta Medica. 85, 2, p. 103-111 9 p.

    Research output: Contribution to journal › Article › peer-review

  96. Novel inhibitors of DNA repair enzyme TDP1 combining monoterpenoid and adamantane fragments

    Mozhaitsev, E. S., Zakharenko, A. L., Suslov, E. V., Korchagina, D. V., Zakharova, O. D., Vasil’eva, I. A., Chepanova, A. A., Black, E., Patel, J., Chand, R., Reynisson, J., Leung, I. K. H., Volcho, K. P., Salakhutdinov, N. F. & Lavrik, O. I., 1 Jan 2019, In: Anti-Cancer Agents in Medicinal Chemistry. 19, 4, p. 463-472 10 p.

    Research output: Contribution to journal › Article › peer-review

  97. Novel tyrosyl-DNA phosphodiesterase 1 inhibitors enhance the therapeutic impact of topoteсan on in vivo tumor models

    Zakharenko, A. L., Luzina, O. A., Sokolov, D. N., Kaledin, V. I., Nikolin, V. P., Popova, N. A., Patel, J., Zakharova, O. D., Chepanova, A. A., Zafar, A., Reynisson, J., Leung, E., Leung, I. K. H., Volcho, K. P., Salakhutdinov, N. F. & Lavrik, O. I., 1 Jan 2019, In: European Journal of Medicinal Chemistry. 161, p. 581-593 13 p.

    Research output: Contribution to journal › Article › peer-review

  98. Poly(ADP-ribose) polymerases in regulation of DNA repair

    Lavrik, O., 1 Jan 2019, In: Biopolymers and Cell. 35, 3, p. 182-183 2 p.

    Research output: Contribution to journal › Article › peer-review

  99. The development of tyrosyl-DNA phosphodyesterase 1 (TDP1) inhibitors based on the amines combining aromatic/heteroaromatic and monoterpenoid moieties

    Mozhaitsev, E., Suslov, E., Demidova, Y., Korchagina, D., Volcho, K., Zakharenko, A., Vasil’eva, I., Kupryushkin, M., Chepanova, A., Ayine-Tora, D. M., Reynisson, J., Salakhutdinov, N. & Lavrik, O., 1 Jan 2019, In: Letters in Drug Design and Discovery. 16, 5, p. 597-605 9 p.

    Research output: Contribution to journal › Article › peer-review

  100. Thermodynamics of the DNA repair process by endonuclease VIII

    Kladova, O. A., Kuznetsov, N. A. & Fedorova, O. S., 1 Jan 2019, In: Acta Naturae. 11, 1, p. 29-37 9 p.

    Research output: Contribution to journal › Article › peer-review

  101. Unrepairable analogous of nucleotide excision repair substrates as a potential anti-cancer drugs

    Evdokimov, A. N., Dol-Gova, E. V., Popov, A. A., Petruse-Va, I. O., Bogachev, S. S. & Lavrik, O. I., 1 Jan 2019, In: Biopolymers and Cell. 35, 3, p. 180-181 2 p.

    Research output: Contribution to journal › Article › peer-review

  102. Unrepairable substrates of nucleotide excision repair and their application to suppress the activity of this repair system

    Popov, A. A., Evdokimov, A. N., Lukyanchikova, N. V., Petruseva, I. O. & Lavrik, O. I., 1 Jan 2019, In: Biopolymers and Cell. 35, 2, p. 107-117 11 p.

    Research output: Contribution to journal › Article › peer-review

  103. Catalytic antibodies as a new evidence of the humoral immune system dysfunction in schizophrenia

    Ermakov, E., Ivanova, S., Semke, A., Dmitrenok, P., Buneva, V. & Nevinsky, G., 2019, In: European Neuropsychopharmacology. 29, p. S586-S586 1 p.

    Research output: Contribution to journal › Meeting Abstract › peer-review

  104. 2018

  105. Changes in cell differentiation and proliferation lead to production of abzymes in EAE mice treated with DNA–Histone complexes

    Aulova, K. S., Toporkova, L. B., Lopatnikova, J. A., Alshevskaya, A. A., Sedykh, S. E., Buneva, V. N., Budde, T., Meuth, S. G., Popova, N. A., Orlovskaya, I. A. & Nevinsky, G. A., 1 Dec 2018, In: Journal of Cellular and Molecular Medicine. 22, 12, p. 5816-5832 17 p.

    Research output: Contribution to journal › Article › peer-review

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