Identification of novel inhibitors for the tyrosyl-DNA-phosphodiesterase 1 (Tdp1) mutant SCAN1 using virtual screening

Original language	English
Article number	115234
Number of pages	11
Journal	Bioorganic and Medicinal Chemistry
Volume	28
Issue number	1
DOIs	https://doi.org/10.1016/j.bmc.2019.115234
Publication status	Published - 1 Jan 2020

Coumarin, Dicoumarin, Spinocerebellar ataxia syndrome with axonal neuropathy (SCAN1), Tyrosyl-DNA phosphodiesterase 1 (TDP1), β-carboline, HUMAN-CELLS, EMPIRICAL SCORING FUNCTIONS, TOPOISOMERASE-I, VANADATE, FRAGMENTS, ENHANCE, DAMAGE REPAIR, CAMPTOTHECIN, PROTEIN-LIGAND DOCKING, beta-carboline, BINDING

ID: 22978737