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The genome of the offspring of a Neanderthal mother and a Denisovan father. / Slon, Viviane; Mafessoni, Fabrizio; Vernot, Benjamin et al.

In: Nature, Vol. 561, No. 7721, 06.09.2018, p. 113-116.

Research output: Contribution to journal › Article › peer-review

Harvard

Slon, V, Mafessoni, F, Vernot, B, de Filippo, C, Grote, S, Viola, B, Hajdinjak, M, Peyrégne, S, Nagel, S, Brown, S, Douka, K, Higham, T, Kozlikin, MB, Shunkov, MV, Derevianko, AP, Kelso, J, Meyer, M, Prüfer, K & Pääbo, S 2018, 'The genome of the offspring of a Neanderthal mother and a Denisovan father', Nature, vol. 561, no. 7721, pp. 113-116. https://doi.org/10.1038/s41586-018-0455-x

APA

Slon, V., Mafessoni, F., Vernot, B., de Filippo, C., Grote, S., Viola, B., Hajdinjak, M., Peyrégne, S., Nagel, S., Brown, S., Douka, K., Higham, T., Kozlikin, M. B., Shunkov, M. V., Derevianko, A. P., Kelso, J., Meyer, M., Prüfer, K., & Pääbo, S. (2018). The genome of the offspring of a Neanderthal mother and a Denisovan father. Nature, 561(7721), 113-116. https://doi.org/10.1038/s41586-018-0455-x

Vancouver

Slon V, Mafessoni F, Vernot B, de Filippo C, Grote S, Viola B et al. The genome of the offspring of a Neanderthal mother and a Denisovan father. Nature. 2018 Sept 6;561(7721):113-116. doi: 10.1038/s41586-018-0455-x

Author

Slon, Viviane ; Mafessoni, Fabrizio ; Vernot, Benjamin et al. / The genome of the offspring of a Neanderthal mother and a Denisovan father. In: Nature. 2018 ; Vol. 561, No. 7721. pp. 113-116.

BibTeX

@article{88bbbe46788e4cac86abab105edef238,
title = "The genome of the offspring of a Neanderthal mother and a Denisovan father",
abstract = "Neanderthals and Denisovans are extinct groups of hominins that separated from each other more than 390,000 years ago1,2. Here we present the genome of {\textquoteleft}Denisova 11{\textquoteright}, a bone fragment from Denisova Cave (Russia)3 and show that it comes from an individual who had a Neanderthal mother and a Denisovan father. The father, whose genome bears traces of Neanderthal ancestry, came from a population related to a later Denisovan found in the cave4–6. The mother came from a population more closely related to Neanderthals who lived later in Europe2,7 than to an earlier Neanderthal found in Denisova Cave8, suggesting that migrations of Neanderthals between eastern and western Eurasia occurred sometime after 120,000 years ago. The finding of a first-generation Neanderthal–Denisovan offspring among the small number of archaic specimens sequenced to date suggests that mixing between Late Pleistocene hominin groups was common when they met.",
keywords = "Alleles, Animals, Fathers, Female, Gene Flow/genetics, Genome, Genomics, History, Ancient, Hominidae/genetics, Humans, Hybridization, Genetic/genetics, Male, Mothers, Neanderthals/genetics, Time Factors, GENETIC HISTORY, SIBERIA, DNA ANALYSIS, CAVE, ASIA, SEQUENCE, HOMININ, READ ALIGNMENT, ANCIENT, BURROWS-WHEELER TRANSFORM",
author = "Viviane Slon and Fabrizio Mafessoni and Benjamin Vernot and {de Filippo}, Cesare and Steffi Grote and Bence Viola and Mateja Hajdinjak and St{\'e}phane Peyr{\'e}gne and Sarah Nagel and Samantha Brown and Katerina Douka and Tom Higham and Kozlikin, {Maxim B.} and Shunkov, {Michael V.} and Derevianko, {Anatoly P.} and Janet Kelso and Matthias Meyer and Kay Pr{\"u}fer and Svante P{\"a}{\"a}bo",
year = "2018",
month = sep,
day = "6",
doi = "10.1038/s41586-018-0455-x",
language = "English",
volume = "561",
pages = "113--116",
journal = "Nature",
issn = "0028-0836",
publisher = "Springer Nature",
number = "7721",

}

RIS

TY - JOUR

T1 - The genome of the offspring of a Neanderthal mother and a Denisovan father

AU - Slon, Viviane

AU - Mafessoni, Fabrizio

AU - Vernot, Benjamin

AU - de Filippo, Cesare

AU - Grote, Steffi

AU - Viola, Bence

AU - Hajdinjak, Mateja

AU - Peyrégne, Stéphane

AU - Nagel, Sarah

AU - Brown, Samantha

AU - Douka, Katerina

AU - Higham, Tom

AU - Kozlikin, Maxim B.

AU - Shunkov, Michael V.

AU - Derevianko, Anatoly P.

AU - Kelso, Janet

AU - Meyer, Matthias

AU - Prüfer, Kay

AU - Pääbo, Svante

PY - 2018/9/6

Y1 - 2018/9/6

N2 - Neanderthals and Denisovans are extinct groups of hominins that separated from each other more than 390,000 years ago1,2. Here we present the genome of ‘Denisova 11’, a bone fragment from Denisova Cave (Russia)3 and show that it comes from an individual who had a Neanderthal mother and a Denisovan father. The father, whose genome bears traces of Neanderthal ancestry, came from a population related to a later Denisovan found in the cave4–6. The mother came from a population more closely related to Neanderthals who lived later in Europe2,7 than to an earlier Neanderthal found in Denisova Cave8, suggesting that migrations of Neanderthals between eastern and western Eurasia occurred sometime after 120,000 years ago. The finding of a first-generation Neanderthal–Denisovan offspring among the small number of archaic specimens sequenced to date suggests that mixing between Late Pleistocene hominin groups was common when they met.

AB - Neanderthals and Denisovans are extinct groups of hominins that separated from each other more than 390,000 years ago1,2. Here we present the genome of ‘Denisova 11’, a bone fragment from Denisova Cave (Russia)3 and show that it comes from an individual who had a Neanderthal mother and a Denisovan father. The father, whose genome bears traces of Neanderthal ancestry, came from a population related to a later Denisovan found in the cave4–6. The mother came from a population more closely related to Neanderthals who lived later in Europe2,7 than to an earlier Neanderthal found in Denisova Cave8, suggesting that migrations of Neanderthals between eastern and western Eurasia occurred sometime after 120,000 years ago. The finding of a first-generation Neanderthal–Denisovan offspring among the small number of archaic specimens sequenced to date suggests that mixing between Late Pleistocene hominin groups was common when they met.

KW - Alleles

KW - Animals

KW - Fathers

KW - Female

KW - Gene Flow/genetics

KW - Genome

KW - Genomics

KW - History, Ancient

KW - Hominidae/genetics

KW - Humans

KW - Hybridization, Genetic/genetics

KW - Male

KW - Mothers

KW - Neanderthals/genetics

KW - Time Factors

KW - GENETIC HISTORY

KW - SIBERIA

KW - DNA ANALYSIS

KW - CAVE

KW - ASIA

KW - SEQUENCE

KW - HOMININ

KW - READ ALIGNMENT

KW - ANCIENT

KW - BURROWS-WHEELER TRANSFORM

UR - http://www.scopus.com/inward/record.url?scp=85052909898&partnerID=8YFLogxK

U2 - 10.1038/s41586-018-0455-x

DO - 10.1038/s41586-018-0455-x

M3 - Article

C2 - 30135579

AN - SCOPUS:85052909898

VL - 561

SP - 113

EP - 116

JO - Nature

JF - Nature

SN - 0028-0836

IS - 7721

ER -

ID: 16484288