Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование
The genome of the offspring of a Neanderthal mother and a Denisovan father. / Slon, Viviane; Mafessoni, Fabrizio; Vernot, Benjamin и др.
в: Nature, Том 561, № 7721, 06.09.2018, стр. 113-116.Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование
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TY - JOUR
T1 - The genome of the offspring of a Neanderthal mother and a Denisovan father
AU - Slon, Viviane
AU - Mafessoni, Fabrizio
AU - Vernot, Benjamin
AU - de Filippo, Cesare
AU - Grote, Steffi
AU - Viola, Bence
AU - Hajdinjak, Mateja
AU - Peyrégne, Stéphane
AU - Nagel, Sarah
AU - Brown, Samantha
AU - Douka, Katerina
AU - Higham, Tom
AU - Kozlikin, Maxim B.
AU - Shunkov, Michael V.
AU - Derevianko, Anatoly P.
AU - Kelso, Janet
AU - Meyer, Matthias
AU - Prüfer, Kay
AU - Pääbo, Svante
PY - 2018/9/6
Y1 - 2018/9/6
N2 - Neanderthals and Denisovans are extinct groups of hominins that separated from each other more than 390,000 years ago1,2. Here we present the genome of ‘Denisova 11’, a bone fragment from Denisova Cave (Russia)3 and show that it comes from an individual who had a Neanderthal mother and a Denisovan father. The father, whose genome bears traces of Neanderthal ancestry, came from a population related to a later Denisovan found in the cave4–6. The mother came from a population more closely related to Neanderthals who lived later in Europe2,7 than to an earlier Neanderthal found in Denisova Cave8, suggesting that migrations of Neanderthals between eastern and western Eurasia occurred sometime after 120,000 years ago. The finding of a first-generation Neanderthal–Denisovan offspring among the small number of archaic specimens sequenced to date suggests that mixing between Late Pleistocene hominin groups was common when they met.
AB - Neanderthals and Denisovans are extinct groups of hominins that separated from each other more than 390,000 years ago1,2. Here we present the genome of ‘Denisova 11’, a bone fragment from Denisova Cave (Russia)3 and show that it comes from an individual who had a Neanderthal mother and a Denisovan father. The father, whose genome bears traces of Neanderthal ancestry, came from a population related to a later Denisovan found in the cave4–6. The mother came from a population more closely related to Neanderthals who lived later in Europe2,7 than to an earlier Neanderthal found in Denisova Cave8, suggesting that migrations of Neanderthals between eastern and western Eurasia occurred sometime after 120,000 years ago. The finding of a first-generation Neanderthal–Denisovan offspring among the small number of archaic specimens sequenced to date suggests that mixing between Late Pleistocene hominin groups was common when they met.
KW - Alleles
KW - Animals
KW - Fathers
KW - Female
KW - Gene Flow/genetics
KW - Genome
KW - Genomics
KW - History, Ancient
KW - Hominidae/genetics
KW - Humans
KW - Hybridization, Genetic/genetics
KW - Male
KW - Mothers
KW - Neanderthals/genetics
KW - Time Factors
KW - GENETIC HISTORY
KW - SIBERIA
KW - DNA ANALYSIS
KW - CAVE
KW - ASIA
KW - SEQUENCE
KW - HOMININ
KW - READ ALIGNMENT
KW - ANCIENT
KW - BURROWS-WHEELER TRANSFORM
UR - http://www.scopus.com/inward/record.url?scp=85052909898&partnerID=8YFLogxK
U2 - 10.1038/s41586-018-0455-x
DO - 10.1038/s41586-018-0455-x
M3 - Article
C2 - 30135579
AN - SCOPUS:85052909898
VL - 561
SP - 113
EP - 116
JO - Nature
JF - Nature
SN - 0028-0836
IS - 7721
ER -
ID: 16484288