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Singlet Oxygen Production and Biological Activity of Hexanuclear Chalcocyanide Rhenium Cluster Complexes [{Re6Q8}(CN)6]4- (Q = S, Se, Te). / Solovieva, Anastasiya O.; Kirakci, Kaplan; Ivanov, Anton A. et al.

In: Inorganic Chemistry, Vol. 56, No. 21, 06.11.2017, p. 13491-13499.

Research output: Contribution to journal › Article › peer-review

Harvard

Solovieva, AO, Kirakci, K, Ivanov, AA, Kubát, P, Pozmogova, TN, Miroshnichenko, SM, Vorontsova, EV, Chechushkov, AV, Trifonova, KE, Fufaeva, MS, Kretov, EI, Mironov, YV, Poveshchenko, AF, Lang, K & Shestopalov, MA 2017, 'Singlet Oxygen Production and Biological Activity of Hexanuclear Chalcocyanide Rhenium Cluster Complexes [{Re6Q8}(CN)6]4- (Q = S, Se, Te)', Inorganic Chemistry, vol. 56, no. 21, pp. 13491-13499. https://doi.org/10.1021/acs.inorgchem.7b02212

APA

Solovieva, A. O., Kirakci, K., Ivanov, A. A., Kubát, P., Pozmogova, T. N., Miroshnichenko, S. M., Vorontsova, E. V., Chechushkov, A. V., Trifonova, K. E., Fufaeva, M. S., Kretov, E. I., Mironov, Y. V., Poveshchenko, A. F., Lang, K., & Shestopalov, M. A. (2017). Singlet Oxygen Production and Biological Activity of Hexanuclear Chalcocyanide Rhenium Cluster Complexes [{Re6Q8}(CN)6]4- (Q = S, Se, Te). Inorganic Chemistry, 56(21), 13491-13499. https://doi.org/10.1021/acs.inorgchem.7b02212

Vancouver

Solovieva AO, Kirakci K, Ivanov AA, Kubát P, Pozmogova TN, Miroshnichenko SM et al. Singlet Oxygen Production and Biological Activity of Hexanuclear Chalcocyanide Rhenium Cluster Complexes [{Re6Q8}(CN)6]4- (Q = S, Se, Te). Inorganic Chemistry. 2017 Nov 6;56(21):13491-13499. doi: 10.1021/acs.inorgchem.7b02212

Author

Solovieva, Anastasiya O. ; Kirakci, Kaplan ; Ivanov, Anton A. et al. / Singlet Oxygen Production and Biological Activity of Hexanuclear Chalcocyanide Rhenium Cluster Complexes [{Re6Q8}(CN)6]4- (Q = S, Se, Te). In: Inorganic Chemistry. 2017 ; Vol. 56, No. 21. pp. 13491-13499.

BibTeX

@article{50156db2ee3c400682c0e154d1099516,
title = "Singlet Oxygen Production and Biological Activity of Hexanuclear Chalcocyanide Rhenium Cluster Complexes [{Re6Q8}(CN)6]4- (Q = S, Se, Te)",
abstract = "Octahedral rhenium cluster complexes have recently emerged as relevant building blocks for the design of singlet oxygen photosensitizing materials toward biological applications such as blue-light photodynamic therapy. However, their singlet oxygen generation ability as well as biological properties have been studied only superficially. Herein we investigate in detail the singlet oxygen photogeneration, dark and photoinduced cytotoxicity, cellular uptake kinetics, cellular localization and in vitro photoinduced oxidative stress, and photodynamic cytotoxicity of the series of octahedral rhenium cluster complexes [{Re6Q8}(CN)6]4-, where Q = S, Se, Te. Our results demonstrate that the selenium-containing complex possesses optimal properties in terms of absorption and singlet oxygen productivity. These features coupled with the cellular internalization and low dark toxicity lead to the first photoinduced cytotoxic effect observed for a molecular [{M6Q8}L6] complex, making it a promising object for further study in terms of blue-light PDT.",
keywords = "PHOTOPHYSICAL PROPERTIES, MOLECULAR-OXYGEN, IODIDE CLUSTER, LUMINESCENCE, CYTOTOXICITY, LIGANDS, POLYMER, SERIES, STATE, BR",
author = "Solovieva, {Anastasiya O.} and Kaplan Kirakci and Ivanov, {Anton A.} and Pavel Kub{\'a}t and Pozmogova, {Tatiana N.} and Miroshnichenko, {Svetlana M.} and Vorontsova, {Elena V.} and Chechushkov, {Anton V.} and Trifonova, {Kristina E.} and Fufaeva, {Maria S.} and Kretov, {Evgeniy I.} and Mironov, {Yuri V.} and Poveshchenko, {Alexander F.} and Kamil Lang and Shestopalov, {Michael A.}",
year = "2017",
month = nov,
day = "6",
doi = "10.1021/acs.inorgchem.7b02212",
language = "English",
volume = "56",
pages = "13491--13499",
journal = "Inorganic Chemistry",
issn = "0020-1669",
publisher = "American Chemical Society",
number = "21",

}

RIS

TY - JOUR

T1 - Singlet Oxygen Production and Biological Activity of Hexanuclear Chalcocyanide Rhenium Cluster Complexes [{Re6Q8}(CN)6]4- (Q = S, Se, Te)

AU - Solovieva, Anastasiya O.

AU - Kirakci, Kaplan

AU - Ivanov, Anton A.

AU - Kubát, Pavel

AU - Pozmogova, Tatiana N.

AU - Miroshnichenko, Svetlana M.

AU - Vorontsova, Elena V.

AU - Chechushkov, Anton V.

AU - Trifonova, Kristina E.

AU - Fufaeva, Maria S.

AU - Kretov, Evgeniy I.

AU - Mironov, Yuri V.

AU - Poveshchenko, Alexander F.

AU - Lang, Kamil

AU - Shestopalov, Michael A.

PY - 2017/11/6

Y1 - 2017/11/6

N2 - Octahedral rhenium cluster complexes have recently emerged as relevant building blocks for the design of singlet oxygen photosensitizing materials toward biological applications such as blue-light photodynamic therapy. However, their singlet oxygen generation ability as well as biological properties have been studied only superficially. Herein we investigate in detail the singlet oxygen photogeneration, dark and photoinduced cytotoxicity, cellular uptake kinetics, cellular localization and in vitro photoinduced oxidative stress, and photodynamic cytotoxicity of the series of octahedral rhenium cluster complexes [{Re6Q8}(CN)6]4-, where Q = S, Se, Te. Our results demonstrate that the selenium-containing complex possesses optimal properties in terms of absorption and singlet oxygen productivity. These features coupled with the cellular internalization and low dark toxicity lead to the first photoinduced cytotoxic effect observed for a molecular [{M6Q8}L6] complex, making it a promising object for further study in terms of blue-light PDT.

AB - Octahedral rhenium cluster complexes have recently emerged as relevant building blocks for the design of singlet oxygen photosensitizing materials toward biological applications such as blue-light photodynamic therapy. However, their singlet oxygen generation ability as well as biological properties have been studied only superficially. Herein we investigate in detail the singlet oxygen photogeneration, dark and photoinduced cytotoxicity, cellular uptake kinetics, cellular localization and in vitro photoinduced oxidative stress, and photodynamic cytotoxicity of the series of octahedral rhenium cluster complexes [{Re6Q8}(CN)6]4-, where Q = S, Se, Te. Our results demonstrate that the selenium-containing complex possesses optimal properties in terms of absorption and singlet oxygen productivity. These features coupled with the cellular internalization and low dark toxicity lead to the first photoinduced cytotoxic effect observed for a molecular [{M6Q8}L6] complex, making it a promising object for further study in terms of blue-light PDT.

KW - PHOTOPHYSICAL PROPERTIES

KW - MOLECULAR-OXYGEN

KW - IODIDE CLUSTER

KW - LUMINESCENCE

KW - CYTOTOXICITY

KW - LIGANDS

KW - POLYMER

KW - SERIES

KW - STATE

KW - BR

UR - http://www.scopus.com/inward/record.url?scp=85033408326&partnerID=8YFLogxK

U2 - 10.1021/acs.inorgchem.7b02212

DO - 10.1021/acs.inorgchem.7b02212

M3 - Article

C2 - 28990789

AN - SCOPUS:85033408326

VL - 56

SP - 13491

EP - 13499

JO - Inorganic Chemistry

JF - Inorganic Chemistry

SN - 0020-1669

IS - 21

ER -

ID: 9699444