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Pt-Decorated Boron Nitride Nanosheets as Artificial Nanozyme for Detection of Dopamine. / Ivanova, Mariia N.; Grayfer, Ekaterina D.; Plotnikova, Elena E. et al.

In: ACS Applied Materials and Interfaces, Vol. 11, No. 25, 26.06.2019, p. 22102-22112.

Research output: Contribution to journalArticlepeer-review

Harvard

Ivanova, MN, Grayfer, ED, Plotnikova, EE, Kibis, LS, Darabdhara, G, Boruah, PK, Das, MR & Fedorov, VE 2019, 'Pt-Decorated Boron Nitride Nanosheets as Artificial Nanozyme for Detection of Dopamine', ACS Applied Materials and Interfaces, vol. 11, no. 25, pp. 22102-22112. https://doi.org/10.1021/acsami.9b04144

APA

Ivanova, M. N., Grayfer, E. D., Plotnikova, E. E., Kibis, L. S., Darabdhara, G., Boruah, P. K., Das, M. R., & Fedorov, V. E. (2019). Pt-Decorated Boron Nitride Nanosheets as Artificial Nanozyme for Detection of Dopamine. ACS Applied Materials and Interfaces, 11(25), 22102-22112. https://doi.org/10.1021/acsami.9b04144

Vancouver

Ivanova MN, Grayfer ED, Plotnikova EE, Kibis LS, Darabdhara G, Boruah PK et al. Pt-Decorated Boron Nitride Nanosheets as Artificial Nanozyme for Detection of Dopamine. ACS Applied Materials and Interfaces. 2019 Jun 26;11(25):22102-22112. doi: 10.1021/acsami.9b04144

Author

Ivanova, Mariia N. ; Grayfer, Ekaterina D. ; Plotnikova, Elena E. et al. / Pt-Decorated Boron Nitride Nanosheets as Artificial Nanozyme for Detection of Dopamine. In: ACS Applied Materials and Interfaces. 2019 ; Vol. 11, No. 25. pp. 22102-22112.

BibTeX

@article{6fdc3780a6364e11871d27d59a8d85da,
title = "Pt-Decorated Boron Nitride Nanosheets as Artificial Nanozyme for Detection of Dopamine",
abstract = "Over the past decade, nanosized metal oxides, metals, and bimetallic particles have been actively researched as enzyme mimetic nanomaterials. However, the common issues with individual nanoparticles (NPs) are stabilization, reproducibility, and blocking of active sites by surfactants. These problems promote further studies of composite materials, where NPs are spread on supports, such as graphene derivatives or dichalcogenide nanosheets. Another promising type of support for NPs is the few-layered hexagonal boron nitride (hBN). In this study, we develop surfactant-free nanocomposites containing Pt NPs dispersed on chemically modified hydrophilic hBN nanosheets (hBNNSs). Ascorbic acid was used as a reducing agent for the chemical reduction of the Pt salt in the presence of hBNNS aqueous colloid, resulting in Pt/hBNNS nanocomposites, which were thoroughly characterized with X-ray diffraction, transmission electron microscopy, dynamic light scattering, and X-ray photoelectron and infrared spectroscopies. Similar to graphene oxide binding the metal NPs more efficiently than pure graphene, hydrophilic hBNNSs well stabilize Pt NPs, with particle size down to around 8 nm. We further demonstrate for the first time that Pt/hBNNS nanocomposites exhibit peroxidase-like catalytic activity, accelerating the oxidation of the classical colorless peroxidase substrate 3,3′,5,5′-tetramethylbenzidine (TMB) to its corresponding blue-colored oxidized product in the presence of H2O2. Kinetic and mechanism studies involving terephthalic acid and isopropanol as a fluorescent probe and an •OH radical scavenger, respectively, proved that Pt/hBNNSs assist H2O2 decomposition to active oxygen species (•OH), which are responsible for TMB oxidation. The Pt/hBNNS nanocomposite-assisted oxidation of TMB provides an effective platform for the colorimetric detection of dopamine, an important biomolecule. The presence of increased amounts of dopamine gradually inhibits the catalytic activity of Pt/hBNNSs for the oxidation of TMB by H2O2, thus enabling selective sensing of dopamine down to 0.76 μM, even in the presence of common interfering molecules and on real blood serum samples. The present investigation on Pt/hBNNSs contributes to the knowledge of hBN-based nanocomposites and discovers their new usage as nanomaterials with good enzyme-mimicking activity and dopamine-sensing properties.",
keywords = "boron nitride nanosheets, enzyme mimetics, nanoparticle decoration, peroxidase-like activity, platinum nanoparticles, GOLD NANOPARTICLES, EXFOLIATION, OXIDE, GRAPHENE, COLORIMETRIC DETECTION, ASCORBIC-ACID, SILVER NANOPARTICLES, OXIDATIVE DEHYDROGENATION, CATALYTIC-ACTIVITY, PEROXIDASE-LIKE ACTIVITY",
author = "Ivanova, {Mariia N.} and Grayfer, {Ekaterina D.} and Plotnikova, {Elena E.} and Kibis, {Lidiya S.} and Gitashree Darabdhara and Boruah, {Purna K.} and Das, {Manash R.} and Fedorov, {Vladimir E.}",
year = "2019",
month = jun,
day = "26",
doi = "10.1021/acsami.9b04144",
language = "English",
volume = "11",
pages = "22102--22112",
journal = "ACS applied materials & interfaces",
issn = "1944-8244",
publisher = "American Chemical Society",
number = "25",

}

RIS

TY - JOUR

T1 - Pt-Decorated Boron Nitride Nanosheets as Artificial Nanozyme for Detection of Dopamine

AU - Ivanova, Mariia N.

AU - Grayfer, Ekaterina D.

AU - Plotnikova, Elena E.

AU - Kibis, Lidiya S.

AU - Darabdhara, Gitashree

AU - Boruah, Purna K.

AU - Das, Manash R.

AU - Fedorov, Vladimir E.

PY - 2019/6/26

Y1 - 2019/6/26

N2 - Over the past decade, nanosized metal oxides, metals, and bimetallic particles have been actively researched as enzyme mimetic nanomaterials. However, the common issues with individual nanoparticles (NPs) are stabilization, reproducibility, and blocking of active sites by surfactants. These problems promote further studies of composite materials, where NPs are spread on supports, such as graphene derivatives or dichalcogenide nanosheets. Another promising type of support for NPs is the few-layered hexagonal boron nitride (hBN). In this study, we develop surfactant-free nanocomposites containing Pt NPs dispersed on chemically modified hydrophilic hBN nanosheets (hBNNSs). Ascorbic acid was used as a reducing agent for the chemical reduction of the Pt salt in the presence of hBNNS aqueous colloid, resulting in Pt/hBNNS nanocomposites, which were thoroughly characterized with X-ray diffraction, transmission electron microscopy, dynamic light scattering, and X-ray photoelectron and infrared spectroscopies. Similar to graphene oxide binding the metal NPs more efficiently than pure graphene, hydrophilic hBNNSs well stabilize Pt NPs, with particle size down to around 8 nm. We further demonstrate for the first time that Pt/hBNNS nanocomposites exhibit peroxidase-like catalytic activity, accelerating the oxidation of the classical colorless peroxidase substrate 3,3′,5,5′-tetramethylbenzidine (TMB) to its corresponding blue-colored oxidized product in the presence of H2O2. Kinetic and mechanism studies involving terephthalic acid and isopropanol as a fluorescent probe and an •OH radical scavenger, respectively, proved that Pt/hBNNSs assist H2O2 decomposition to active oxygen species (•OH), which are responsible for TMB oxidation. The Pt/hBNNS nanocomposite-assisted oxidation of TMB provides an effective platform for the colorimetric detection of dopamine, an important biomolecule. The presence of increased amounts of dopamine gradually inhibits the catalytic activity of Pt/hBNNSs for the oxidation of TMB by H2O2, thus enabling selective sensing of dopamine down to 0.76 μM, even in the presence of common interfering molecules and on real blood serum samples. The present investigation on Pt/hBNNSs contributes to the knowledge of hBN-based nanocomposites and discovers their new usage as nanomaterials with good enzyme-mimicking activity and dopamine-sensing properties.

AB - Over the past decade, nanosized metal oxides, metals, and bimetallic particles have been actively researched as enzyme mimetic nanomaterials. However, the common issues with individual nanoparticles (NPs) are stabilization, reproducibility, and blocking of active sites by surfactants. These problems promote further studies of composite materials, where NPs are spread on supports, such as graphene derivatives or dichalcogenide nanosheets. Another promising type of support for NPs is the few-layered hexagonal boron nitride (hBN). In this study, we develop surfactant-free nanocomposites containing Pt NPs dispersed on chemically modified hydrophilic hBN nanosheets (hBNNSs). Ascorbic acid was used as a reducing agent for the chemical reduction of the Pt salt in the presence of hBNNS aqueous colloid, resulting in Pt/hBNNS nanocomposites, which were thoroughly characterized with X-ray diffraction, transmission electron microscopy, dynamic light scattering, and X-ray photoelectron and infrared spectroscopies. Similar to graphene oxide binding the metal NPs more efficiently than pure graphene, hydrophilic hBNNSs well stabilize Pt NPs, with particle size down to around 8 nm. We further demonstrate for the first time that Pt/hBNNS nanocomposites exhibit peroxidase-like catalytic activity, accelerating the oxidation of the classical colorless peroxidase substrate 3,3′,5,5′-tetramethylbenzidine (TMB) to its corresponding blue-colored oxidized product in the presence of H2O2. Kinetic and mechanism studies involving terephthalic acid and isopropanol as a fluorescent probe and an •OH radical scavenger, respectively, proved that Pt/hBNNSs assist H2O2 decomposition to active oxygen species (•OH), which are responsible for TMB oxidation. The Pt/hBNNS nanocomposite-assisted oxidation of TMB provides an effective platform for the colorimetric detection of dopamine, an important biomolecule. The presence of increased amounts of dopamine gradually inhibits the catalytic activity of Pt/hBNNSs for the oxidation of TMB by H2O2, thus enabling selective sensing of dopamine down to 0.76 μM, even in the presence of common interfering molecules and on real blood serum samples. The present investigation on Pt/hBNNSs contributes to the knowledge of hBN-based nanocomposites and discovers their new usage as nanomaterials with good enzyme-mimicking activity and dopamine-sensing properties.

KW - boron nitride nanosheets

KW - enzyme mimetics

KW - nanoparticle decoration

KW - peroxidase-like activity

KW - platinum nanoparticles

KW - GOLD NANOPARTICLES

KW - EXFOLIATION

KW - OXIDE

KW - GRAPHENE

KW - COLORIMETRIC DETECTION

KW - ASCORBIC-ACID

KW - SILVER NANOPARTICLES

KW - OXIDATIVE DEHYDROGENATION

KW - CATALYTIC-ACTIVITY

KW - PEROXIDASE-LIKE ACTIVITY

UR - http://www.scopus.com/inward/record.url?scp=85067963264&partnerID=8YFLogxK

U2 - 10.1021/acsami.9b04144

DO - 10.1021/acsami.9b04144

M3 - Article

C2 - 31124654

AN - SCOPUS:85067963264

VL - 11

SP - 22102

EP - 22112

JO - ACS applied materials & interfaces

JF - ACS applied materials & interfaces

SN - 1944-8244

IS - 25

ER -

ID: 20707229