101 - 120 out of 142Page size: 20
  1. 2019

  2. Novel tyrosyl-DNA phosphodiesterase 1 inhibitors enhance the therapeutic impact of topoteсan on in vivo tumor models

    Zakharenko, A. L., Luzina, O. A., Sokolov, D. N., Kaledin, V. I., Nikolin, V. P., Popova, N. A., Patel, J., Zakharova, O. D., Chepanova, A. A., Zafar, A., Reynisson, J., Leung, E., Leung, I. K. H., Volcho, K. P., Salakhutdinov, N. F. & Lavrik, O. I., 1 Jan 2019, In: European Journal of Medicinal Chemistry. 161, p. 581-593 13 p.

    Research output: Contribution to journal › Article › peer-review

  3. Poly(ADP-ribose) polymerases in regulation of DNA repair

    Lavrik, O., 1 Jan 2019, In: Biopolymers and Cell. 35, 3, p. 182-183 2 p.

    Research output: Contribution to journal › Article › peer-review

  4. The development of tyrosyl-DNA phosphodyesterase 1 (TDP1) inhibitors based on the amines combining aromatic/heteroaromatic and monoterpenoid moieties

    Mozhaitsev, E., Suslov, E., Demidova, Y., Korchagina, D., Volcho, K., Zakharenko, A., Vasil’eva, I., Kupryushkin, M., Chepanova, A., Ayine-Tora, D. M., Reynisson, J., Salakhutdinov, N. & Lavrik, O., 1 Jan 2019, In: Letters in Drug Design and Discovery. 16, 5, p. 597-605 9 p.

    Research output: Contribution to journal › Article › peer-review

  5. Unrepairable analogous of nucleotide excision repair substrates as a potential anti-cancer drugs

    Evdokimov, A. N., Dol-Gova, E. V., Popov, A. A., Petruse-Va, I. O., Bogachev, S. S. & Lavrik, O. I., 1 Jan 2019, In: Biopolymers and Cell. 35, 3, p. 180-181 2 p.

    Research output: Contribution to journal › Article › peer-review

  6. Unrepairable substrates of nucleotide excision repair and their application to suppress the activity of this repair system

    Popov, A. A., Evdokimov, A. N., Lukyanchikova, N. V., Petruseva, I. O. & Lavrik, O. I., 1 Jan 2019, In: Biopolymers and Cell. 35, 2, p. 107-117 11 p.

    Research output: Contribution to journal › Article › peer-review

  7. 2018

  8. Replication protein A as a modulator of the poly(ADP-ribose)polymerase 1 activity

    Maltseva, E. A., Krasikova, Y. S., Sukhanova, M. V., Rechkunova, N. I. & Lavrik, O. I., 1 Dec 2018, In: DNA Repair. 72, p. 28-38 11 p.

    Research output: Contribution to journal › Article › peer-review

  9. Excision of Carbohydrate-Modified dNMP Analogues from DNA 3' end by Human Apurinic/Apyrimidinic Endonuclease 1 (APE1) and Tyrosyl-DNA Phosphodiesterase 1 (TDP1)

    Dyrkheeva, N. S., Lebedeva, N. A., Sherstyuk, Y. V., Abramova, T. V., Silnikov, V. N. & Lavrik, O. I., 1 Nov 2018, In: Molecular Biology. 52, 6, p. 922-928 7 p.

    Research output: Contribution to journal › Article › peer-review

  10. Excision of Carbohydrate-Modified dNMP Analogues from DNA 3' end by Human Apurinic/Apyrimidinic Endonuclease 1 (APE1) and Tyrosyl-DNA Phosphodiesterase 1 (TDP1)

    Dyrkheeva, N. S., Lebedeva, N. A., Sherstyuk, Y. V., Abramova, T. V., Silnikov, V. N. & Lavrik, O. I., 1 Nov 2018, In: Molekuliarnaia biologiia. 52, 6, p. 1066-1073 8 p.

    Research output: Contribution to journal › Article › peer-review

  11. A novel class of tyrosyl-DNA phosphodiesterase 1 inhibitors that contains the octahydro-2H-chromen-4-ol scaffold

    Li-Zhulanov, N. S., Zakharenko, A. L., Chepanova, A. A., Patel, J., Zafar, A., Volcho, K. P., Salakhutdinov, N. F., Reynisson, J., Leung, I. K. H. & Lavrik, O. I., 26 Sept 2018, In: Molecules. 23, 10, 14 p., 2468.

    Research output: Contribution to journal › Article › peer-review

  12. Novel group of tyrosyl-DNA-phosphodiesterase 1 inhibitors based on disaccharide nucleosides as drug prototypes for anti-cancer therapy

    Komarova, A. O., Drenichev, M. S., Dyrkheeva, N. S., Kulikova, I. V., Oslovsky, V. E., Zakharova, O. D., Zakharenko, A. L., Mikhailov, S. N. & Lavrik, O. I., 7 Sept 2018, In: Journal of Enzyme Inhibition and Medicinal Chemistry. 33, 1, p. 1415-1429 15 p.

    Research output: Contribution to journal › Article › peer-review

  13. A New DNA Break Repair Pathway Involving PARP3 and Base Excision Repair Proteins

    Belousova, E. A., Kutuzov, M. M., Ivankina, P. A., Ishchenko, A. A. & Lavrik, O. I., 1 Sept 2018, In: Doklady Biochemistry and Biophysics. 482, 1, p. 233-237 5 p.

    Research output: Contribution to journal › Article › peer-review

  14. Synthesis and evaluation of aryliden- and hetarylidenfuranone derivatives of usnic acid as highly potent Tdp1 inhibitors

    Zakharova, O., Luzina, O., Zakharenko, A., Sokolov, D., Filimonov, A., Dyrkheeva, N., Chepanova, A., Ilina, E., Ilyina, A., Klabenkova, K., Chelobanov, B., Stetsenko, D., Zafar, A., Eurtivong, C., Reynisson, J., Volcho, K., Salakhutdinov, N. & Lavrik, O., 15 Aug 2018, In: Bioorganic and Medicinal Chemistry. 26, 15, p. 4470-4480 11 p.

    Research output: Contribution to journal › Article › peer-review

  15. Synthesis and Inhibitory Properties of Imines Containing Monoterpenoid and Adamantane Fragments Against DNA Repair Enzyme Tyrosyl-DNA Phosphodiesterase 1 (Tdp1)

    Zakharenko, A. L., Mozhaitsev, E. S., Suslov, E. V., Korchagina, D. V., Volcho, K. P., Salakhutdinov, N. F. & Lavrik, O. I., 1 Jul 2018, In: Chemistry of Natural Compounds. 54, 4, p. 672-676 5 p.

    Research output: Contribution to journal › Article › peer-review

  16. Unusual interaction of human apurinic/apyrimidinic endonuclease 1 (APE1) with abasic sites via the Schiff-base-dependent mechanism

    Ilina, E. S., Khodyreva, S. N. & Lavrik, O. I., 1 Jul 2018, In: Biochimie. 150, p. 88-99 12 p.

    Research output: Contribution to journal › Article › peer-review

  17. Interaction of PARP1 and its regulatory protein, YB-1, is modulated by PAR

    Naumenko, K., Alemasova, E. & Lavrik, O., Jul 2018, In: FEBS Open Bio. 8, p. 139-139 1 p.

    Research output: Contribution to journal › Meeting Abstract › peer-review

  18. The multifunctional protein YB-1 potentiates PARP1 activity and decreases the efficiency of PARP1 inhibitors

    Alemasova, E. E., Naumenko, K. N., Kurgina, T. A., Anarbaev, R. O. & Lavrik, O. I., 1 May 2018, In: Oncotarget. 9, 34, p. 23349-23365 17 p.

    Research output: Contribution to journal › Article › peer-review

  19. DNA Bearing Bulky Fluorescent and Photoreactive Damage in Both Strands as Substrates of the Nucleotide Excision Repair System

    Lukyanchikova, N. V., Petruseva, I. O., Evdokimov, A. N., Koroleva, L. S. & Lavrik, O. I., 27 Apr 2018, In: Molekuliarnaia biologiia. 52, 2, p. 277-288 12 p.

    Research output: Contribution to journal › Article › peer-review

  20. Comprehensive analysis of telomerase inhibition by gallotannin

    Savelyev, N., Baykuzina, P., Dokudovskaya, S., Lavrik, O., Rubtsova, M. & Dontsova, O., 10 Apr 2018, In: Oncotarget. 9, 27, p. 18712-18719 8 p.

    Research output: Contribution to journal › Article › peer-review

  21. Protein–Protein Interactions in DNA Base Excision Repair

    Moor, N. A. & Lavrik, O. I., 1 Apr 2018, In: Biochemistry (Moscow). 83, 4, p. 411-422 12 p.

    Research output: Contribution to journal › Review article › peer-review

  22. Novel semisynthetic derivatives of bile acids as effective tyrosyl-DNA phosphodiesterase 1 inhibitors

    Salomatina, O. V., Popadyuk, I. I., Zakharenko, A. L., Zakharova, O. D., Fadeev, D. S., Komarova, N. I., Reynisson, J., Arabshahi, H. J., Chand, R., Volcho, K. P., Salakhutdinov, N. F. & Lavrik, O. I., 17 Mar 2018, In: Molecules. 23, 3, 19 p., 679.

    Research output: Contribution to journal › Article › peer-review

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