Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование
The phylogeny of class b flavoprotein monooxygenases and the origin of the yucca protein family. / Turnaev, Igor I.; Gunbin, Konstantin V.; Suslov, Valentin V. и др.
в: Plants, Том 9, № 9, 1092, 01.09.2020, стр. 1-22.Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование
}
TY - JOUR
T1 - The phylogeny of class b flavoprotein monooxygenases and the origin of the yucca protein family
AU - Turnaev, Igor I.
AU - Gunbin, Konstantin V.
AU - Suslov, Valentin V.
AU - Akberdin, Ilya R.
AU - Kolchanov, Nikolay A.
AU - Afonnikov, Dmitry A.
N1 - Publisher Copyright: © 2020 by the authors. Licensee MDPI, Basel, Switzerland.
PY - 2020/9/1
Y1 - 2020/9/1
N2 - YUCCA (YUCCA flavin-dependent monooxygenase) is one of the two enzymes of the main auxin biosynthesis pathway (tryptophan aminotransferase enzyme (TAA)/YUCCA) in land plants. The evolutionary origin of the YUCCA family is currently controversial: YUCCAs are assumed to have emerged via a horizontal gene transfer (HGT) from bacteria to the most recent common ancestor (MRCA) of land plants or to have inherited it from their ancestor, the charophyte algae. To refine YUCCA origin, we performed a phylogenetic analysis of the class B flavoprotein monooxygenases and comparative analysis of the sequences belonging to different families of this protein class. We distinguished a new protein family, named type IIb flavin-containing monooxygenases (FMOs), which comprises homologs of YUCCA from Rhodophyta, Chlorophyta, and Charophyta, land plant proteins, and FMO-E,-F, and-G of the bacterium Rhodococcus jostii RHA1. The type IIb FMOs differ considerably in the sites and domain composition from the other families of class B flavoprotein monooxygenases, YUCCAs included. The phylogenetic analysis also demonstrated that the type IIb FMO clade is not a sibling clade of YUCCAs. We have also identified the bacterial protein group named YUC-like FMOs as the closest to YUCCA homologs. Our results support the hypothesis of the emergence of YUCCA via HGT from bacteria to MRCA of land plants.
AB - YUCCA (YUCCA flavin-dependent monooxygenase) is one of the two enzymes of the main auxin biosynthesis pathway (tryptophan aminotransferase enzyme (TAA)/YUCCA) in land plants. The evolutionary origin of the YUCCA family is currently controversial: YUCCAs are assumed to have emerged via a horizontal gene transfer (HGT) from bacteria to the most recent common ancestor (MRCA) of land plants or to have inherited it from their ancestor, the charophyte algae. To refine YUCCA origin, we performed a phylogenetic analysis of the class B flavoprotein monooxygenases and comparative analysis of the sequences belonging to different families of this protein class. We distinguished a new protein family, named type IIb flavin-containing monooxygenases (FMOs), which comprises homologs of YUCCA from Rhodophyta, Chlorophyta, and Charophyta, land plant proteins, and FMO-E,-F, and-G of the bacterium Rhodococcus jostii RHA1. The type IIb FMOs differ considerably in the sites and domain composition from the other families of class B flavoprotein monooxygenases, YUCCAs included. The phylogenetic analysis also demonstrated that the type IIb FMO clade is not a sibling clade of YUCCAs. We have also identified the bacterial protein group named YUC-like FMOs as the closest to YUCCA homologs. Our results support the hypothesis of the emergence of YUCCA via HGT from bacteria to MRCA of land plants.
KW - Auxin biosynthesis
KW - Charophytes
KW - Flavin-dependent monooxygenase
KW - Horizontal gene transfer
KW - Phylogeny
KW - YUCCA
KW - charophytes
KW - horizontal gene transfer
KW - flavin-dependent monooxygenase
KW - MODES
KW - auxin biosynthesis
KW - EVOLUTION
KW - ENZYMES
KW - SEQUENCE
KW - ALGAE
KW - phylogeny
KW - FLAVIN-CONTAINING MONOOXYGENASES
KW - PLANT AUXIN BIOSYNTHESIS
KW - ARABIDOPSIS
UR - http://www.scopus.com/inward/record.url?scp=85090607952&partnerID=8YFLogxK
U2 - 10.3390/plants9091092
DO - 10.3390/plants9091092
M3 - Article
C2 - 32854417
AN - SCOPUS:85090607952
VL - 9
SP - 1
EP - 22
JO - Plants
JF - Plants
SN - 2223-7747
IS - 9
M1 - 1092
ER -
ID: 25309087