Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование
The measurement of the neutron yield of the7li(P,n)7be reaction in lithium targets. / Bikchurina, Marina; Bykov, Timofey; Kasatov, Dmitrii и др.
в: Biology, Том 10, № 9, 824, 09.2021.Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование
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TY - JOUR
T1 - The measurement of the neutron yield of the7li(P,n)7be reaction in lithium targets
AU - Bikchurina, Marina
AU - Bykov, Timofey
AU - Kasatov, Dmitrii
AU - Kolesnikov, Iaroslav
AU - Makarov, Aleksandr
AU - Shchudlo, Ivan
AU - Sokolova, Evgeniia
AU - Taskaev, Sergey
N1 - Funding Information: Funding: This research was funded the Russian Foundation for Basic Research, contract number № 19-32-90119. Publisher Copyright: © 2021 by the authors. Licensee MDPI, Basel, Switzerland.
PY - 2021/9
Y1 - 2021/9
N2 - A compact accelerator-based neutron source has been proposed and created at the Budker Institute of Nuclear Physics in Novosibirsk, Russia. An original design tandem accelerator is used to provide a proton beam. The neutron flux is generated as a result of the7Li(p,n)7Be threshold reaction using the solid lithium target. A beam shaping assembly is applied to convert this flux into a beam of epithermal neutrons with characteristics suitable for BNCT. The BNCT technique is being tested in in vitro and in vivo studies, and dosimetry methods are being developed. Currently, the BNCT technique has entered into clinical practice in the world: after successful clinical trials, two clinics in Japan began treating patients, and four more BNCT clinics are ready to start operating. The neutron source proposed at the Budker Institute of Nuclear Physics served as a prototype for a facility created for a clinic in Xiamen (China). It is planned to equip the National Medical Research Center of Oncology (Moscow, Russia) and National Oncological Hadron Therapy Center (Pavia, Italy) with the same neutron sources. Due to the impending use of an accelerator neutron source for treating patients, the validation of the neutron yield of the7Li(p,n)7Be reaction in lithium metal targets is required. The theoretical neutron yield has not been evaluated experimentally so far.
AB - A compact accelerator-based neutron source has been proposed and created at the Budker Institute of Nuclear Physics in Novosibirsk, Russia. An original design tandem accelerator is used to provide a proton beam. The neutron flux is generated as a result of the7Li(p,n)7Be threshold reaction using the solid lithium target. A beam shaping assembly is applied to convert this flux into a beam of epithermal neutrons with characteristics suitable for BNCT. The BNCT technique is being tested in in vitro and in vivo studies, and dosimetry methods are being developed. Currently, the BNCT technique has entered into clinical practice in the world: after successful clinical trials, two clinics in Japan began treating patients, and four more BNCT clinics are ready to start operating. The neutron source proposed at the Budker Institute of Nuclear Physics served as a prototype for a facility created for a clinic in Xiamen (China). It is planned to equip the National Medical Research Center of Oncology (Moscow, Russia) and National Oncological Hadron Therapy Center (Pavia, Italy) with the same neutron sources. Due to the impending use of an accelerator neutron source for treating patients, the validation of the neutron yield of the7Li(p,n)7Be reaction in lithium metal targets is required. The theoretical neutron yield has not been evaluated experimentally so far.
KW - Backscattering protons
KW - Boron neutron capture therapy
KW - Charged particle accelerator
KW - Lithium target
KW - Neutron source
KW - γ-radiation spectrometer
UR - http://www.scopus.com/inward/record.url?scp=85114046628&partnerID=8YFLogxK
U2 - 10.3390/biology10090824
DO - 10.3390/biology10090824
M3 - Article
C2 - 34571701
AN - SCOPUS:85114046628
VL - 10
JO - Biology
JF - Biology
SN - 2079-7737
IS - 9
M1 - 824
ER -
ID: 34143993