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The measurement of the neutron yield of the7li(P,n)7be reaction in lithium targets. / Bikchurina, Marina; Bykov, Timofey; Kasatov, Dmitrii et al.

In: Biology, Vol. 10, No. 9, 824, 09.2021.

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Bikchurina M, Bykov T, Kasatov D, Kolesnikov I, Makarov A, Shchudlo I et al. The measurement of the neutron yield of the7li(P,n)7be reaction in lithium targets. Biology. 2021 Sept;10(9):824. doi: 10.3390/biology10090824

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@article{65511480deae4e168c817df1d32e9da5,
title = "The measurement of the neutron yield of the7li(P,n)7be reaction in lithium targets",
abstract = "A compact accelerator-based neutron source has been proposed and created at the Budker Institute of Nuclear Physics in Novosibirsk, Russia. An original design tandem accelerator is used to provide a proton beam. The neutron flux is generated as a result of the7Li(p,n)7Be threshold reaction using the solid lithium target. A beam shaping assembly is applied to convert this flux into a beam of epithermal neutrons with characteristics suitable for BNCT. The BNCT technique is being tested in in vitro and in vivo studies, and dosimetry methods are being developed. Currently, the BNCT technique has entered into clinical practice in the world: after successful clinical trials, two clinics in Japan began treating patients, and four more BNCT clinics are ready to start operating. The neutron source proposed at the Budker Institute of Nuclear Physics served as a prototype for a facility created for a clinic in Xiamen (China). It is planned to equip the National Medical Research Center of Oncology (Moscow, Russia) and National Oncological Hadron Therapy Center (Pavia, Italy) with the same neutron sources. Due to the impending use of an accelerator neutron source for treating patients, the validation of the neutron yield of the7Li(p,n)7Be reaction in lithium metal targets is required. The theoretical neutron yield has not been evaluated experimentally so far.",
keywords = "Backscattering protons, Boron neutron capture therapy, Charged particle accelerator, Lithium target, Neutron source, γ-radiation spectrometer",
author = "Marina Bikchurina and Timofey Bykov and Dmitrii Kasatov and Iaroslav Kolesnikov and Aleksandr Makarov and Ivan Shchudlo and Evgeniia Sokolova and Sergey Taskaev",
note = "Funding Information: Funding: This research was funded the Russian Foundation for Basic Research, contract number № 19-32-90119. Publisher Copyright: {\textcopyright} 2021 by the authors. Licensee MDPI, Basel, Switzerland.",
year = "2021",
month = sep,
doi = "10.3390/biology10090824",
language = "English",
volume = "10",
journal = "Biology",
issn = "2079-7737",
publisher = "Multidisciplinary Digital Publishing Institute (MDPI)",
number = "9",

}

RIS

TY - JOUR

T1 - The measurement of the neutron yield of the7li(P,n)7be reaction in lithium targets

AU - Bikchurina, Marina

AU - Bykov, Timofey

AU - Kasatov, Dmitrii

AU - Kolesnikov, Iaroslav

AU - Makarov, Aleksandr

AU - Shchudlo, Ivan

AU - Sokolova, Evgeniia

AU - Taskaev, Sergey

N1 - Funding Information: Funding: This research was funded the Russian Foundation for Basic Research, contract number № 19-32-90119. Publisher Copyright: © 2021 by the authors. Licensee MDPI, Basel, Switzerland.

PY - 2021/9

Y1 - 2021/9

N2 - A compact accelerator-based neutron source has been proposed and created at the Budker Institute of Nuclear Physics in Novosibirsk, Russia. An original design tandem accelerator is used to provide a proton beam. The neutron flux is generated as a result of the7Li(p,n)7Be threshold reaction using the solid lithium target. A beam shaping assembly is applied to convert this flux into a beam of epithermal neutrons with characteristics suitable for BNCT. The BNCT technique is being tested in in vitro and in vivo studies, and dosimetry methods are being developed. Currently, the BNCT technique has entered into clinical practice in the world: after successful clinical trials, two clinics in Japan began treating patients, and four more BNCT clinics are ready to start operating. The neutron source proposed at the Budker Institute of Nuclear Physics served as a prototype for a facility created for a clinic in Xiamen (China). It is planned to equip the National Medical Research Center of Oncology (Moscow, Russia) and National Oncological Hadron Therapy Center (Pavia, Italy) with the same neutron sources. Due to the impending use of an accelerator neutron source for treating patients, the validation of the neutron yield of the7Li(p,n)7Be reaction in lithium metal targets is required. The theoretical neutron yield has not been evaluated experimentally so far.

AB - A compact accelerator-based neutron source has been proposed and created at the Budker Institute of Nuclear Physics in Novosibirsk, Russia. An original design tandem accelerator is used to provide a proton beam. The neutron flux is generated as a result of the7Li(p,n)7Be threshold reaction using the solid lithium target. A beam shaping assembly is applied to convert this flux into a beam of epithermal neutrons with characteristics suitable for BNCT. The BNCT technique is being tested in in vitro and in vivo studies, and dosimetry methods are being developed. Currently, the BNCT technique has entered into clinical practice in the world: after successful clinical trials, two clinics in Japan began treating patients, and four more BNCT clinics are ready to start operating. The neutron source proposed at the Budker Institute of Nuclear Physics served as a prototype for a facility created for a clinic in Xiamen (China). It is planned to equip the National Medical Research Center of Oncology (Moscow, Russia) and National Oncological Hadron Therapy Center (Pavia, Italy) with the same neutron sources. Due to the impending use of an accelerator neutron source for treating patients, the validation of the neutron yield of the7Li(p,n)7Be reaction in lithium metal targets is required. The theoretical neutron yield has not been evaluated experimentally so far.

KW - Backscattering protons

KW - Boron neutron capture therapy

KW - Charged particle accelerator

KW - Lithium target

KW - Neutron source

KW - γ-radiation spectrometer

UR - http://www.scopus.com/inward/record.url?scp=85114046628&partnerID=8YFLogxK

U2 - 10.3390/biology10090824

DO - 10.3390/biology10090824

M3 - Article

C2 - 34571701

AN - SCOPUS:85114046628

VL - 10

JO - Biology

JF - Biology

SN - 2079-7737

IS - 9

M1 - 824

ER -

ID: 34143993