Результаты исследований: Научные публикации в периодических изданиях › обзорная статья › Рецензирование
The genetic history of Ice Age Europe. / Fu, Qiaomei; Posth, Cosimo; Hajdinjak, Mateja и др.
в: Nature, Том 534, № 7606, 02.05.2016, стр. 200-205.Результаты исследований: Научные публикации в периодических изданиях › обзорная статья › Рецензирование
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TY - JOUR
T1 - The genetic history of Ice Age Europe
AU - Fu, Qiaomei
AU - Posth, Cosimo
AU - Hajdinjak, Mateja
AU - Petr, Martin
AU - Mallick, Swapan
AU - Fernandes, Daniel
AU - Furtwängler, Anja
AU - Haak, Wolfgang
AU - Meyer, Matthias
AU - Mittnik, Alissa
AU - Nickel, Birgit
AU - Peltzer, Alexander
AU - Rohland, Nadin
AU - Slon, Viviane
AU - Talamo, Sahra
AU - Lazaridis, Iosif
AU - Lipson, Mark
AU - Mathieson, Iain
AU - Schiffels, Stephan
AU - Skoglund, Pontus
AU - Derevianko, Anatoly P.
AU - Drozdov, Nikolai
AU - Slavinsky, Vyacheslav
AU - Tsybankov, Alexander
AU - Cremonesi, Renata Grifoni
AU - Mallegni, Francesco
AU - Gély, Bernard
AU - Vacca, Eligio
AU - Morales, Manuel R.González
AU - Straus, Lawrence G.
AU - Neugebauer-Maresch, Christine
AU - Teschler-Nicola, Maria
AU - Constantin, Silviu
AU - Moldovan, Oana Teodora
AU - Benazzi, Stefano
AU - Peresani, Marco
AU - Coppola, Donato
AU - Lari, Martina
AU - Ricci, Stefano
AU - Ronchitelli, Annamaria
AU - Valentin, Frédérique
AU - Thevenet, Corinne
AU - Wehrberger, Kurt
AU - Grigorescu, Dan
AU - Rougier, Hélène
AU - Crevecoeur, Isabelle
AU - Flas, Damien
AU - Semal, Patrick
AU - Mannino, Marcello A.
AU - Cupillard, Christophe
AU - Bocherens, Hervé
AU - Conard, Nicholas J.
AU - Harvati, Katerina
AU - Moiseyev, Vyacheslav
AU - Drucker, Dorothée G.
AU - Svoboda, Jiří
AU - Richards, Michael P.
AU - Caramelli, David
AU - Pinhasi, Ron
AU - Kelso, Janet
AU - Patterson, Nick
AU - Krause, Johannes
AU - Pääbo, Svante
AU - Reich, David
PY - 2016/5/2
Y1 - 2016/5/2
N2 - Modern humans arrived in Europe ∼45,000 years ago, but little is known about their genetic composition before the start of farming ∼8,500 years ago. Here we analyse genome-wide data from 51 Eurasians from ∼45,000-7,000 years ago. Over this time, the proportion of Neanderthal DNA decreased from 3-6% to around 2%, consistent with natural selection against Neanderthal variants in modern humans. Whereas there is no evidence of the earliest modern humans in Europe contributing to the genetic composition of present-day Europeans, all individuals between ∼37,000 and ∼14,000 years ago descended from a single founder population which forms part of the ancestry of present-day Europeans. An ∼35,000-year-old individual from northwest Europe represents an early branch of this founder population which was then displaced across a broad region, before reappearing in southwest Europe at the height of the last Ice Age ∼19,000 years ago. During the major warming period after ∼14,000 years ago, a genetic component related to present-day Near Easterners became widespread in Europe. These results document how population turnover and migration have been recurring themes of European prehistory.
AB - Modern humans arrived in Europe ∼45,000 years ago, but little is known about their genetic composition before the start of farming ∼8,500 years ago. Here we analyse genome-wide data from 51 Eurasians from ∼45,000-7,000 years ago. Over this time, the proportion of Neanderthal DNA decreased from 3-6% to around 2%, consistent with natural selection against Neanderthal variants in modern humans. Whereas there is no evidence of the earliest modern humans in Europe contributing to the genetic composition of present-day Europeans, all individuals between ∼37,000 and ∼14,000 years ago descended from a single founder population which forms part of the ancestry of present-day Europeans. An ∼35,000-year-old individual from northwest Europe represents an early branch of this founder population which was then displaced across a broad region, before reappearing in southwest Europe at the height of the last Ice Age ∼19,000 years ago. During the major warming period after ∼14,000 years ago, a genetic component related to present-day Near Easterners became widespread in Europe. These results document how population turnover and migration have been recurring themes of European prehistory.
UR - http://www.scopus.com/inward/record.url?scp=84969820697&partnerID=8YFLogxK
U2 - 10.1038/nature17993
DO - 10.1038/nature17993
M3 - Review article
C2 - 27135931
AN - SCOPUS:84969820697
VL - 534
SP - 200
EP - 205
JO - Nature
JF - Nature
SN - 0028-0836
IS - 7606
ER -
ID: 25377151