Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование
Synthetic Transformations of Sesquiterpene Lactones. 11.* Conjugates Based on Caffeine and Eudesmanolides with N-Containing Linkers. / Reshetnikov, D. V.; Patrushev, S. S.; Shults, E. E.
в: Chemistry of Natural Compounds, Том 56, № 5, 01.09.2020, стр. 855-860.Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование
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TY - JOUR
T1 - Synthetic Transformations of Sesquiterpene Lactones. 11.* Conjugates Based on Caffeine and Eudesmanolides with N-Containing Linkers
AU - Reshetnikov, D. V.
AU - Patrushev, S. S.
AU - Shults, E. E.
N1 - Publisher Copyright: © 2020, Springer Science+Business Media, LLC, part of Springer Nature. Copyright: Copyright 2020 Elsevier B.V., All rights reserved.
PY - 2020/9/1
Y1 - 2020/9/1
N2 - 8-(Aminoalkylamino)caffeine or 8-(piperazinyl)caffeine were formed in high yields by reacting 8-bromo- or 8-chlorocaffeine with linear and cyclic diamines using microwave-assisted organic synthesis. These amines were highly reactive in Michael reactions with sesquiterpene lactones containing active methylene groups. Conjugates with caffeine and eudesmanolide moieties bonded by a N-containing linker were synthesized.
AB - 8-(Aminoalkylamino)caffeine or 8-(piperazinyl)caffeine were formed in high yields by reacting 8-bromo- or 8-chlorocaffeine with linear and cyclic diamines using microwave-assisted organic synthesis. These amines were highly reactive in Michael reactions with sesquiterpene lactones containing active methylene groups. Conjugates with caffeine and eudesmanolide moieties bonded by a N-containing linker were synthesized.
KW - caffeine
KW - eudesmanolides
KW - methylenelactones
KW - Michael reaction
UR - http://www.scopus.com/inward/record.url?scp=85090943791&partnerID=8YFLogxK
U2 - 10.1007/s10600-020-03169-x
DO - 10.1007/s10600-020-03169-x
M3 - Article
AN - SCOPUS:85090943791
VL - 56
SP - 855
EP - 860
JO - Chemistry of Natural Compounds
JF - Chemistry of Natural Compounds
SN - 0009-3130
IS - 5
ER -
ID: 25627203