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Synthetic Transformations of Sesquiterpene Lactones. 11.* Conjugates Based on Caffeine and Eudesmanolides with N-Containing Linkers. / Reshetnikov, D. V.; Patrushev, S. S.; Shults, E. E.

In: Chemistry of Natural Compounds, Vol. 56, No. 5, 01.09.2020, p. 855-860.

Research output: Contribution to journal › Article › peer-review

Harvard

Reshetnikov, DV, Patrushev, SS & Shults, EE 2020, 'Synthetic Transformations of Sesquiterpene Lactones. 11.* Conjugates Based on Caffeine and Eudesmanolides with N-Containing Linkers', Chemistry of Natural Compounds, vol. 56, no. 5, pp. 855-860. https://doi.org/10.1007/s10600-020-03169-x

APA

Reshetnikov, D. V., Patrushev, S. S., & Shults, E. E. (2020). Synthetic Transformations of Sesquiterpene Lactones. 11.* Conjugates Based on Caffeine and Eudesmanolides with N-Containing Linkers. Chemistry of Natural Compounds, 56(5), 855-860. https://doi.org/10.1007/s10600-020-03169-x

Vancouver

Reshetnikov DV, Patrushev SS, Shults EE. Synthetic Transformations of Sesquiterpene Lactones. 11.* Conjugates Based on Caffeine and Eudesmanolides with N-Containing Linkers. Chemistry of Natural Compounds. 2020 Sept 1;56(5):855-860. doi: 10.1007/s10600-020-03169-x

Author

Reshetnikov, D. V. ; Patrushev, S. S. ; Shults, E. E. / Synthetic Transformations of Sesquiterpene Lactones. 11.* Conjugates Based on Caffeine and Eudesmanolides with N-Containing Linkers. In: Chemistry of Natural Compounds. 2020 ; Vol. 56, No. 5. pp. 855-860.

BibTeX

@article{676180d188f145a7bf33629239054666,
title = "Synthetic Transformations of Sesquiterpene Lactones. 11.* Conjugates Based on Caffeine and Eudesmanolides with N-Containing Linkers",
abstract = "8-(Aminoalkylamino)caffeine or 8-(piperazinyl)caffeine were formed in high yields by reacting 8-bromo- or 8-chlorocaffeine with linear and cyclic diamines using microwave-assisted organic synthesis. These amines were highly reactive in Michael reactions with sesquiterpene lactones containing active methylene groups. Conjugates with caffeine and eudesmanolide moieties bonded by a N-containing linker were synthesized.",
keywords = "caffeine, eudesmanolides, methylenelactones, Michael reaction",
author = "Reshetnikov, {D. V.} and Patrushev, {S. S.} and Shults, {E. E.}",
note = "Publisher Copyright: {\textcopyright} 2020, Springer Science+Business Media, LLC, part of Springer Nature. Copyright: Copyright 2020 Elsevier B.V., All rights reserved.",
year = "2020",
month = sep,
day = "1",
doi = "10.1007/s10600-020-03169-x",
language = "English",
volume = "56",
pages = "855--860",
journal = "Chemistry of Natural Compounds",
issn = "0009-3130",
publisher = "Springer New York",
number = "5",

}

RIS

TY - JOUR

T1 - Synthetic Transformations of Sesquiterpene Lactones. 11.* Conjugates Based on Caffeine and Eudesmanolides with N-Containing Linkers

AU - Reshetnikov, D. V.

AU - Patrushev, S. S.

AU - Shults, E. E.

N1 - Publisher Copyright: © 2020, Springer Science+Business Media, LLC, part of Springer Nature. Copyright: Copyright 2020 Elsevier B.V., All rights reserved.

PY - 2020/9/1

Y1 - 2020/9/1

N2 - 8-(Aminoalkylamino)caffeine or 8-(piperazinyl)caffeine were formed in high yields by reacting 8-bromo- or 8-chlorocaffeine with linear and cyclic diamines using microwave-assisted organic synthesis. These amines were highly reactive in Michael reactions with sesquiterpene lactones containing active methylene groups. Conjugates with caffeine and eudesmanolide moieties bonded by a N-containing linker were synthesized.

AB - 8-(Aminoalkylamino)caffeine or 8-(piperazinyl)caffeine were formed in high yields by reacting 8-bromo- or 8-chlorocaffeine with linear and cyclic diamines using microwave-assisted organic synthesis. These amines were highly reactive in Michael reactions with sesquiterpene lactones containing active methylene groups. Conjugates with caffeine and eudesmanolide moieties bonded by a N-containing linker were synthesized.

KW - caffeine

KW - eudesmanolides

KW - methylenelactones

KW - Michael reaction

UR - http://www.scopus.com/inward/record.url?scp=85090943791&partnerID=8YFLogxK

U2 - 10.1007/s10600-020-03169-x

DO - 10.1007/s10600-020-03169-x

M3 - Article

AN - SCOPUS:85090943791

VL - 56

SP - 855

EP - 860

JO - Chemistry of Natural Compounds

JF - Chemistry of Natural Compounds

SN - 0009-3130

IS - 5

ER -

ID: 25627203