Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование
Synthetic transformations of higher terpenoids. XXXV.* synthesis and cytotoxicity of macroheterocyclic compounds based on lambertianic acid. / Kharitonov, Yu V.; Shakirov, M. M.; Pokrovskii, M. A. и др.
в: Chemistry of Natural Compounds, Том 53, № 1, 01.01.2017, стр. 77-82.Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование
}
TY - JOUR
T1 - Synthetic transformations of higher terpenoids. XXXV.* synthesis and cytotoxicity of macroheterocyclic compounds based on lambertianic acid
AU - Kharitonov, Yu V.
AU - Shakirov, M. M.
AU - Pokrovskii, M. A.
AU - Pokrovskii, A. G.
AU - Shul’Ts, E. E.
N1 - Publisher Copyright: © 2017 Springer Science+Business Media New York.
PY - 2017/1/1
Y1 - 2017/1/1
N2 - (17R)-17,18-Dipropargyloxylabda-13,15-diene was synthesized and underwent Cu-catalyzed cycloaddition with 1,10-diazodecane or 1,2-bis(2-azidoethoxy)ethane to produce macroheterocycles of the furanolabdanoid decalin fragment. The macroheterocyclic labdanoids showed significant cytotoxicity in MEL-8, MT-4, and U-937 human tumor cell models.
AB - (17R)-17,18-Dipropargyloxylabda-13,15-diene was synthesized and underwent Cu-catalyzed cycloaddition with 1,10-diazodecane or 1,2-bis(2-azidoethoxy)ethane to produce macroheterocycles of the furanolabdanoid decalin fragment. The macroheterocyclic labdanoids showed significant cytotoxicity in MEL-8, MT-4, and U-937 human tumor cell models.
KW - 1,2,3-triazoles
KW - Cytotoxicity
KW - Dialkynyllabdadienes
KW - Lambertianic acid
KW - Macroheterocycles
UR - http://www.scopus.com/inward/record.url?scp=85013421857&partnerID=8YFLogxK
U2 - 10.1007/s10600-017-1915-5
DO - 10.1007/s10600-017-1915-5
M3 - Article
AN - SCOPUS:85013421857
VL - 53
SP - 77
EP - 82
JO - Chemistry of Natural Compounds
JF - Chemistry of Natural Compounds
SN - 0009-3130
IS - 1
ER -
ID: 8686814