Synthesis of new compounds combining adamantanamine and monoterpene fragments and their antiviral activity against influenza virus A(H1N1)pdm09

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Synthesis of new compounds combining adamantanamine and monoterpene fragments and their antiviral activity against influenza virus A(H1N1)pdm09. / Teplov, George V.; Suslov, Evgeny V.; Zarubaev, Vladimir V. и др.

в: Letters in Drug Design and Discovery, Том 10, № 6, 07.2013, стр. 477-485.

Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование

Harvard

Teplov, GV, Suslov, EV, Zarubaev, VV, Shtro, AA, Karpinskaya, LA, Rogachev, AD, Korchagina, DV, Volcho, KP, Salakhutdinov, NF & Kiselev, OI 2013, 'Synthesis of new compounds combining adamantanamine and monoterpene fragments and their antiviral activity against influenza virus A(H1N1)pdm09', Letters in Drug Design and Discovery, Том. 10, № 6, стр. 477-485. https://doi.org/10.2174/1570180811310060002

APA

Teplov, G. V., Suslov, E. V., Zarubaev, V. V., Shtro, A. A., Karpinskaya, L. A., Rogachev, A. D., Korchagina, D. V., Volcho, K. P., Salakhutdinov, N. F., & Kiselev, O. I. (2013). Synthesis of new compounds combining adamantanamine and monoterpene fragments and their antiviral activity against influenza virus A(H1N1)pdm09. Letters in Drug Design and Discovery, 10(6), 477-485. https://doi.org/10.2174/1570180811310060002

Vancouver

Teplov GV, Suslov EV, Zarubaev VV, Shtro AA, Karpinskaya LA, Rogachev AD и др. Synthesis of new compounds combining adamantanamine and monoterpene fragments and their antiviral activity against influenza virus A(H1N1)pdm09. Letters in Drug Design and Discovery. 2013 июль;10(6):477-485. doi: 10.2174/1570180811310060002

Author

Teplov, George V. ; Suslov, Evgeny V. ; Zarubaev, Vladimir V. и др. / Synthesis of new compounds combining adamantanamine and monoterpene fragments and their antiviral activity against influenza virus A(H1N1)pdm09. в: Letters in Drug Design and Discovery. 2013 ; Том 10, № 6. стр. 477-485.

BibTeX

@article{4401df86d1c343f9b385c5b93664458d,

title = "Synthesis of new compounds combining adamantanamine and monoterpene fragments and their antiviral activity against influenza virus A(H1N1)pdm09",

abstract = "A set of new nitrogen-containing compounds with adamantane and monoterpene frameworks was synthesized. The antiviral activity of the amine products against the influenza virus A/California/07/09 (H1N1)pdm09 was studied. The introduction of a monoterpenoid fragment led to increase of the antiviral activity of adamantylamine derivatives against adamantylamine resistant virus: the selectivity index of the majority of the synthesized amines was higher than that of rimantadine and amantadine.",

keywords = "(H1N1)pdm09, Adamantyamine, Antiviral, Influenza, Monoterpenoid, Resistance",

author = "Teplov, {George V.} and Suslov, {Evgeny V.} and Zarubaev, {Vladimir V.} and Shtro, {Anna A.} and Karpinskaya, {Liubov A.} and Rogachev, {Artem D.} and Korchagina, {Dina V.} and Volcho, {Konstantin P.} and Salakhutdinov, {Nariman F.} and Kiselev, {Oleg I.}",

year = "2013",

month = jul,

doi = "10.2174/1570180811310060002",

language = "English",

volume = "10",

pages = "477--485",

journal = "Letters in Drug Design and Discovery",

issn = "1570-1808",

publisher = "Bentham Science Publishers B.V.",

number = "6",

}

RIS

TY - JOUR

T1 - Synthesis of new compounds combining adamantanamine and monoterpene fragments and their antiviral activity against influenza virus A(H1N1)pdm09

AU - Teplov, George V.

AU - Suslov, Evgeny V.

AU - Zarubaev, Vladimir V.

AU - Shtro, Anna A.

AU - Karpinskaya, Liubov A.

AU - Rogachev, Artem D.

AU - Korchagina, Dina V.

AU - Volcho, Konstantin P.

AU - Salakhutdinov, Nariman F.

AU - Kiselev, Oleg I.

PY - 2013/7

Y1 - 2013/7

N2 - A set of new nitrogen-containing compounds with adamantane and monoterpene frameworks was synthesized. The antiviral activity of the amine products against the influenza virus A/California/07/09 (H1N1)pdm09 was studied. The introduction of a monoterpenoid fragment led to increase of the antiviral activity of adamantylamine derivatives against adamantylamine resistant virus: the selectivity index of the majority of the synthesized amines was higher than that of rimantadine and amantadine.

AB - A set of new nitrogen-containing compounds with adamantane and monoterpene frameworks was synthesized. The antiviral activity of the amine products against the influenza virus A/California/07/09 (H1N1)pdm09 was studied. The introduction of a monoterpenoid fragment led to increase of the antiviral activity of adamantylamine derivatives against adamantylamine resistant virus: the selectivity index of the majority of the synthesized amines was higher than that of rimantadine and amantadine.

KW - (H1N1)pdm09

KW - Adamantyamine

KW - Antiviral

KW - Influenza

KW - Monoterpenoid

KW - Resistance

UR - http://www.scopus.com/inward/record.url?scp=84879756004&partnerID=8YFLogxK

U2 - 10.2174/1570180811310060002

DO - 10.2174/1570180811310060002

M3 - Article

AN - SCOPUS:84879756004

VL - 10

SP - 477

EP - 485

JO - Letters in Drug Design and Discovery

JF - Letters in Drug Design and Discovery

SN - 1570-1808

IS - 6

ER -

ID: 26770376