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Synthesis of new compounds combining adamantanamine and monoterpene fragments and their antiviral activity against influenza virus A(H1N1)pdm09. / Teplov, George V.; Suslov, Evgeny V.; Zarubaev, Vladimir V. et al.

In: Letters in Drug Design and Discovery, Vol. 10, No. 6, 07.2013, p. 477-485.

Research output: Contribution to journal › Article › peer-review

Harvard

Teplov, GV, Suslov, EV, Zarubaev, VV, Shtro, AA, Karpinskaya, LA, Rogachev, AD, Korchagina, DV, Volcho, KP, Salakhutdinov, NF & Kiselev, OI 2013, 'Synthesis of new compounds combining adamantanamine and monoterpene fragments and their antiviral activity against influenza virus A(H1N1)pdm09', Letters in Drug Design and Discovery, vol. 10, no. 6, pp. 477-485. https://doi.org/10.2174/1570180811310060002

APA

Teplov, G. V., Suslov, E. V., Zarubaev, V. V., Shtro, A. A., Karpinskaya, L. A., Rogachev, A. D., Korchagina, D. V., Volcho, K. P., Salakhutdinov, N. F., & Kiselev, O. I. (2013). Synthesis of new compounds combining adamantanamine and monoterpene fragments and their antiviral activity against influenza virus A(H1N1)pdm09. Letters in Drug Design and Discovery, 10(6), 477-485. https://doi.org/10.2174/1570180811310060002

Vancouver

Teplov GV, Suslov EV, Zarubaev VV, Shtro AA, Karpinskaya LA, Rogachev AD et al. Synthesis of new compounds combining adamantanamine and monoterpene fragments and their antiviral activity against influenza virus A(H1N1)pdm09. Letters in Drug Design and Discovery. 2013 Jul;10(6):477-485. doi: 10.2174/1570180811310060002

Author

Teplov, George V. ; Suslov, Evgeny V. ; Zarubaev, Vladimir V. et al. / Synthesis of new compounds combining adamantanamine and monoterpene fragments and their antiviral activity against influenza virus A(H1N1)pdm09. In: Letters in Drug Design and Discovery. 2013 ; Vol. 10, No. 6. pp. 477-485.

BibTeX

@article{4401df86d1c343f9b385c5b93664458d,
title = "Synthesis of new compounds combining adamantanamine and monoterpene fragments and their antiviral activity against influenza virus A(H1N1)pdm09",
abstract = "A set of new nitrogen-containing compounds with adamantane and monoterpene frameworks was synthesized. The antiviral activity of the amine products against the influenza virus A/California/07/09 (H1N1)pdm09 was studied. The introduction of a monoterpenoid fragment led to increase of the antiviral activity of adamantylamine derivatives against adamantylamine resistant virus: the selectivity index of the majority of the synthesized amines was higher than that of rimantadine and amantadine.",
keywords = "(H1N1)pdm09, Adamantyamine, Antiviral, Influenza, Monoterpenoid, Resistance",
author = "Teplov, {George V.} and Suslov, {Evgeny V.} and Zarubaev, {Vladimir V.} and Shtro, {Anna A.} and Karpinskaya, {Liubov A.} and Rogachev, {Artem D.} and Korchagina, {Dina V.} and Volcho, {Konstantin P.} and Salakhutdinov, {Nariman F.} and Kiselev, {Oleg I.}",
note = "Copyright: Copyright 2013 Elsevier B.V., All rights reserved.",
year = "2013",
month = jul,
doi = "10.2174/1570180811310060002",
language = "English",
volume = "10",
pages = "477--485",
journal = "Letters in Drug Design and Discovery",
issn = "1570-1808",
publisher = "Bentham Science Publishers B.V.",
number = "6",

}

RIS

TY - JOUR

T1 - Synthesis of new compounds combining adamantanamine and monoterpene fragments and their antiviral activity against influenza virus A(H1N1)pdm09

AU - Teplov, George V.

AU - Suslov, Evgeny V.

AU - Zarubaev, Vladimir V.

AU - Shtro, Anna A.

AU - Karpinskaya, Liubov A.

AU - Rogachev, Artem D.

AU - Korchagina, Dina V.

AU - Volcho, Konstantin P.

AU - Salakhutdinov, Nariman F.

AU - Kiselev, Oleg I.

N1 - Copyright: Copyright 2013 Elsevier B.V., All rights reserved.

PY - 2013/7

Y1 - 2013/7

N2 - A set of new nitrogen-containing compounds with adamantane and monoterpene frameworks was synthesized. The antiviral activity of the amine products against the influenza virus A/California/07/09 (H1N1)pdm09 was studied. The introduction of a monoterpenoid fragment led to increase of the antiviral activity of adamantylamine derivatives against adamantylamine resistant virus: the selectivity index of the majority of the synthesized amines was higher than that of rimantadine and amantadine.

AB - A set of new nitrogen-containing compounds with adamantane and monoterpene frameworks was synthesized. The antiviral activity of the amine products against the influenza virus A/California/07/09 (H1N1)pdm09 was studied. The introduction of a monoterpenoid fragment led to increase of the antiviral activity of adamantylamine derivatives against adamantylamine resistant virus: the selectivity index of the majority of the synthesized amines was higher than that of rimantadine and amantadine.

KW - (H1N1)pdm09

KW - Adamantyamine

KW - Antiviral

KW - Influenza

KW - Monoterpenoid

KW - Resistance

UR - http://www.scopus.com/inward/record.url?scp=84879756004&partnerID=8YFLogxK

U2 - 10.2174/1570180811310060002

DO - 10.2174/1570180811310060002

M3 - Article

AN - SCOPUS:84879756004

VL - 10

SP - 477

EP - 485

JO - Letters in Drug Design and Discovery

JF - Letters in Drug Design and Discovery

SN - 1570-1808

IS - 6

ER -

ID: 26770376