Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование
Synthesis and Antiviral Properties of Camphor-Derived Iminothiazolidine-4-Ones and 2,3-Dihydrothiazoles. / Oreshko, Vladislav V.; Kovaleva, Kseniya S.; Mordvinova, Ekaterina D. и др.
в: Molecules, Том 27, № 15, 4761, 08.2022.Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование
}
TY - JOUR
T1 - Synthesis and Antiviral Properties of Camphor-Derived Iminothiazolidine-4-Ones and 2,3-Dihydrothiazoles
AU - Oreshko, Vladislav V.
AU - Kovaleva, Kseniya S.
AU - Mordvinova, Ekaterina D.
AU - Yarovaya, Olga I.
AU - Gatilov, Yuri V.
AU - Shcherbakov, Dmitry N.
AU - Bormotov, Nikolai I.
AU - Serova, Olga A.
AU - Shishkina, Larisa N.
AU - Salakhutdinov, Nariman F.
N1 - Funding Information: This work was supported by the Ministry of Science and Higher Education of the Russian Federation (075-15-2020-777). Publisher Copyright: © 2022 by the authors.
PY - 2022/8
Y1 - 2022/8
N2 - A set of heterocyclic products was synthesized from natural (+)-camphor and semi-synthetic (−)-camphor. Then, 2-Imino-4-thiazolidinones and 2,3-dihydrothiazoles were obtained using a three-step procedure. For the synthesized compounds, their antiviral activity against the vaccinia virus and Marburg virus was studied. New promising agents active against both viruses were found among the tested compounds.
AB - A set of heterocyclic products was synthesized from natural (+)-camphor and semi-synthetic (−)-camphor. Then, 2-Imino-4-thiazolidinones and 2,3-dihydrothiazoles were obtained using a three-step procedure. For the synthesized compounds, their antiviral activity against the vaccinia virus and Marburg virus was studied. New promising agents active against both viruses were found among the tested compounds.
KW - heterocyclic compounds
KW - Marburg virus
KW - monoterpenes
KW - monoterpenoids
KW - vaccinia virus
KW - Thiazoles/pharmacology
KW - Antiviral Agents/pharmacology
KW - Camphor/pharmacology
KW - Structure-Activity Relationship
UR - http://www.scopus.com/inward/record.url?scp=85137006227&partnerID=8YFLogxK
UR - https://www.mendeley.com/catalogue/69d1c335-1cbd-32b8-a865-d5bf2b6b7179/
U2 - 10.3390/molecules27154761
DO - 10.3390/molecules27154761
M3 - Article
C2 - 35897931
AN - SCOPUS:85137006227
VL - 27
JO - Molecules
JF - Molecules
SN - 1420-3049
IS - 15
M1 - 4761
ER -
ID: 37068682