Synthesis and Antiviral Properties of Camphor-Derived Iminothiazolidine-4-Ones and 2,3-Dihydrothiazoles

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Synthesis and Antiviral Properties of Camphor-Derived Iminothiazolidine-4-Ones and 2,3-Dihydrothiazoles. / Oreshko, Vladislav V.; Kovaleva, Kseniya S.; Mordvinova, Ekaterina D. et al.

In: Molecules, Vol. 27, No. 15, 4761, 08.2022.

Research output: Contribution to journal › Article › peer-review

Harvard

Oreshko, VV, Kovaleva, KS, Mordvinova, ED, Yarovaya, OI, Gatilov, YV, Shcherbakov, DN, Bormotov, NI, Serova, OA, Shishkina, LN & Salakhutdinov, NF 2022, 'Synthesis and Antiviral Properties of Camphor-Derived Iminothiazolidine-4-Ones and 2,3-Dihydrothiazoles', Molecules, vol. 27, no. 15, 4761. https://doi.org/10.3390/molecules27154761

APA

Oreshko, V. V., Kovaleva, K. S., Mordvinova, E. D., Yarovaya, O. I., Gatilov, Y. V., Shcherbakov, D. N., Bormotov, N. I., Serova, O. A., Shishkina, L. N., & Salakhutdinov, N. F. (2022). Synthesis and Antiviral Properties of Camphor-Derived Iminothiazolidine-4-Ones and 2,3-Dihydrothiazoles. Molecules, 27(15), [4761]. https://doi.org/10.3390/molecules27154761

Vancouver

Oreshko VV, Kovaleva KS, Mordvinova ED, Yarovaya OI, Gatilov YV, Shcherbakov DN et al. Synthesis and Antiviral Properties of Camphor-Derived Iminothiazolidine-4-Ones and 2,3-Dihydrothiazoles. Molecules. 2022 Aug;27(15):4761. doi: 10.3390/molecules27154761

Author

Oreshko, Vladislav V. ; Kovaleva, Kseniya S. ; Mordvinova, Ekaterina D. et al. / Synthesis and Antiviral Properties of Camphor-Derived Iminothiazolidine-4-Ones and 2,3-Dihydrothiazoles. In: Molecules. 2022 ; Vol. 27, No. 15.

BibTeX

@article{0b03a56eeeb04c79888f81f81f56e6cc,

title = "Synthesis and Antiviral Properties of Camphor-Derived Iminothiazolidine-4-Ones and 2,3-Dihydrothiazoles",

abstract = "A set of heterocyclic products was synthesized from natural (+)-camphor and semi-synthetic (−)-camphor. Then, 2-Imino-4-thiazolidinones and 2,3-dihydrothiazoles were obtained using a three-step procedure. For the synthesized compounds, their antiviral activity against the vaccinia virus and Marburg virus was studied. New promising agents active against both viruses were found among the tested compounds.",

keywords = "heterocyclic compounds, Marburg virus, monoterpenes, monoterpenoids, vaccinia virus, Thiazoles/pharmacology, Antiviral Agents/pharmacology, Camphor/pharmacology, Structure-Activity Relationship",

author = "Oreshko, {Vladislav V.} and Kovaleva, {Kseniya S.} and Mordvinova, {Ekaterina D.} and Yarovaya, {Olga I.} and Gatilov, {Yuri V.} and Shcherbakov, {Dmitry N.} and Bormotov, {Nikolai I.} and Serova, {Olga A.} and Shishkina, {Larisa N.} and Salakhutdinov, {Nariman F.}",

note = "Funding Information: This work was supported by the Ministry of Science and Higher Education of the Russian Federation (075-15-2020-777). Publisher Copyright: {\textcopyright} 2022 by the authors.",

year = "2022",

month = aug,

doi = "10.3390/molecules27154761",

language = "English",

volume = "27",

journal = "Molecules",

issn = "1420-3049",

publisher = "Multidisciplinary Digital Publishing Institute (MDPI)",

number = "15",

}

RIS

TY - JOUR

T1 - Synthesis and Antiviral Properties of Camphor-Derived Iminothiazolidine-4-Ones and 2,3-Dihydrothiazoles

AU - Oreshko, Vladislav V.

AU - Kovaleva, Kseniya S.

AU - Mordvinova, Ekaterina D.

AU - Yarovaya, Olga I.

AU - Gatilov, Yuri V.

AU - Shcherbakov, Dmitry N.

AU - Bormotov, Nikolai I.

AU - Serova, Olga A.

AU - Shishkina, Larisa N.

AU - Salakhutdinov, Nariman F.

PY - 2022/8

Y1 - 2022/8

N2 - A set of heterocyclic products was synthesized from natural (+)-camphor and semi-synthetic (−)-camphor. Then, 2-Imino-4-thiazolidinones and 2,3-dihydrothiazoles were obtained using a three-step procedure. For the synthesized compounds, their antiviral activity against the vaccinia virus and Marburg virus was studied. New promising agents active against both viruses were found among the tested compounds.

AB - A set of heterocyclic products was synthesized from natural (+)-camphor and semi-synthetic (−)-camphor. Then, 2-Imino-4-thiazolidinones and 2,3-dihydrothiazoles were obtained using a three-step procedure. For the synthesized compounds, their antiviral activity against the vaccinia virus and Marburg virus was studied. New promising agents active against both viruses were found among the tested compounds.

KW - heterocyclic compounds

KW - Marburg virus

KW - monoterpenes

KW - monoterpenoids

KW - vaccinia virus

KW - Thiazoles/pharmacology

KW - Antiviral Agents/pharmacology

KW - Camphor/pharmacology

KW - Structure-Activity Relationship

UR - http://www.scopus.com/inward/record.url?scp=85137006227&partnerID=8YFLogxK

UR - https://www.mendeley.com/catalogue/69d1c335-1cbd-32b8-a865-d5bf2b6b7179/

U2 - 10.3390/molecules27154761

DO - 10.3390/molecules27154761

M3 - Article

C2 - 35897931

AN - SCOPUS:85137006227

VL - 27

JO - Molecules

JF - Molecules

SN - 1420-3049

IS - 15

M1 - 4761

ER -

ID: 37068682