Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование
Synthesis and analgesic activity of octahydro-2H-chromenols, derivatives of aliphatic ketones. / Il’ina, I. V.; Korchagina, D. V.; Morozova, E. A. и др.
в: Russian Chemical Bulletin, Том 68, № 5, 01.05.2019, стр. 1061-1066.Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование
}
TY - JOUR
T1 - Synthesis and analgesic activity of octahydro-2H-chromenols, derivatives of aliphatic ketones
AU - Il’ina, I. V.
AU - Korchagina, D. V.
AU - Morozova, E. A.
AU - Tolstikova, T. G.
AU - Volcho, K. P.
AU - Salakhutdinov, N. F.
PY - 2019/5/1
Y1 - 2019/5/1
N2 - A series of compounds with a hydrogenated 2H-chromene skeleton was synthesized by the reaction of ketones and available para-menthane monoterpenoid (—)-isopulegol. A condensation product of (—)-isopulegol with the monoterpene ketone l-menthone was synthesized for the first time. The synthesized heterocycles were tested for analgesic activity and compounds with high analgesic activity in the in vivo tests were identified.
AB - A series of compounds with a hydrogenated 2H-chromene skeleton was synthesized by the reaction of ketones and available para-menthane monoterpenoid (—)-isopulegol. A condensation product of (—)-isopulegol with the monoterpene ketone l-menthone was synthesized for the first time. The synthesized heterocycles were tested for analgesic activity and compounds with high analgesic activity in the in vivo tests were identified.
KW - analgesic activity
KW - heterocyclic compounds
KW - monoterpenoids
KW - montmorillonite K10
UR - http://www.scopus.com/inward/record.url?scp=85067041253&partnerID=8YFLogxK
U2 - 10.1007/s11172-019-2520-5
DO - 10.1007/s11172-019-2520-5
M3 - Article
AN - SCOPUS:85067041253
VL - 68
SP - 1061
EP - 1066
JO - Russian Chemical Bulletin
JF - Russian Chemical Bulletin
SN - 1066-5285
IS - 5
ER -
ID: 20583450