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Synthesis and analgesic activity of octahydro-2H-chromenols, derivatives of aliphatic ketones. / Il’ina, I. V.; Korchagina, D. V.; Morozova, E. A. et al.

In: Russian Chemical Bulletin, Vol. 68, No. 5, 01.05.2019, p. 1061-1066.

Research output: Contribution to journal › Article › peer-review

Harvard

Il’ina, IV, Korchagina, DV, Morozova, EA, Tolstikova, TG, Volcho, KP & Salakhutdinov, NF 2019, 'Synthesis and analgesic activity of octahydro-2H-chromenols, derivatives of aliphatic ketones', Russian Chemical Bulletin, vol. 68, no. 5, pp. 1061-1066. https://doi.org/10.1007/s11172-019-2520-5

APA

Il’ina, I. V., Korchagina, D. V., Morozova, E. A., Tolstikova, T. G., Volcho, K. P., & Salakhutdinov, N. F. (2019). Synthesis and analgesic activity of octahydro-2H-chromenols, derivatives of aliphatic ketones. Russian Chemical Bulletin, 68(5), 1061-1066. https://doi.org/10.1007/s11172-019-2520-5

Vancouver

Il’ina IV, Korchagina DV, Morozova EA, Tolstikova TG, Volcho KP, Salakhutdinov NF. Synthesis and analgesic activity of octahydro-2H-chromenols, derivatives of aliphatic ketones. Russian Chemical Bulletin. 2019 May 1;68(5):1061-1066. doi: 10.1007/s11172-019-2520-5

Author

Il’ina, I. V. ; Korchagina, D. V. ; Morozova, E. A. et al. / Synthesis and analgesic activity of octahydro-2H-chromenols, derivatives of aliphatic ketones. In: Russian Chemical Bulletin. 2019 ; Vol. 68, No. 5. pp. 1061-1066.

BibTeX

@article{5c452933d60f47d592253f026654d615,
title = "Synthesis and analgesic activity of octahydro-2H-chromenols, derivatives of aliphatic ketones",
abstract = "A series of compounds with a hydrogenated 2H-chromene skeleton was synthesized by the reaction of ketones and available para-menthane monoterpenoid (—)-isopulegol. A condensation product of (—)-isopulegol with the monoterpene ketone l-menthone was synthesized for the first time. The synthesized heterocycles were tested for analgesic activity and compounds with high analgesic activity in the in vivo tests were identified.",
keywords = "analgesic activity, heterocyclic compounds, monoterpenoids, montmorillonite K10",
author = "Il{\textquoteright}ina, {I. V.} and Korchagina, {D. V.} and Morozova, {E. A.} and Tolstikova, {T. G.} and Volcho, {K. P.} and Salakhutdinov, {N. F.}",
year = "2019",
month = may,
day = "1",
doi = "10.1007/s11172-019-2520-5",
language = "English",
volume = "68",
pages = "1061--1066",
journal = "Russian Chemical Bulletin",
issn = "1066-5285",
publisher = "Springer Nature",
number = "5",

}

RIS

TY - JOUR

T1 - Synthesis and analgesic activity of octahydro-2H-chromenols, derivatives of aliphatic ketones

AU - Il’ina, I. V.

AU - Korchagina, D. V.

AU - Morozova, E. A.

AU - Tolstikova, T. G.

AU - Volcho, K. P.

AU - Salakhutdinov, N. F.

PY - 2019/5/1

Y1 - 2019/5/1

N2 - A series of compounds with a hydrogenated 2H-chromene skeleton was synthesized by the reaction of ketones and available para-menthane monoterpenoid (—)-isopulegol. A condensation product of (—)-isopulegol with the monoterpene ketone l-menthone was synthesized for the first time. The synthesized heterocycles were tested for analgesic activity and compounds with high analgesic activity in the in vivo tests were identified.

AB - A series of compounds with a hydrogenated 2H-chromene skeleton was synthesized by the reaction of ketones and available para-menthane monoterpenoid (—)-isopulegol. A condensation product of (—)-isopulegol with the monoterpene ketone l-menthone was synthesized for the first time. The synthesized heterocycles were tested for analgesic activity and compounds with high analgesic activity in the in vivo tests were identified.

KW - analgesic activity

KW - heterocyclic compounds

KW - monoterpenoids

KW - montmorillonite K10

UR - http://www.scopus.com/inward/record.url?scp=85067041253&partnerID=8YFLogxK

U2 - 10.1007/s11172-019-2520-5

DO - 10.1007/s11172-019-2520-5

M3 - Article

AN - SCOPUS:85067041253

VL - 68

SP - 1061

EP - 1066

JO - Russian Chemical Bulletin

JF - Russian Chemical Bulletin

SN - 1066-5285

IS - 5

ER -

ID: 20583450