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Structural and Molecular Kinetic Features of Activities of DNA Polymerases. / Kuznetsova, Aleksandra A.; Fedorova, Olga S.; Kuznetsov, Nikita A.

в: International Journal of Molecular Sciences, Том 23, № 12, 6373, 01.06.2022.

Результаты исследований: Научные публикации в периодических изданиях › обзорная статья › Рецензирование

Harvard

Kuznetsova, AA, Fedorova, OS & Kuznetsov, NA 2022, 'Structural and Molecular Kinetic Features of Activities of DNA Polymerases', International Journal of Molecular Sciences, Том. 23, № 12, 6373. https://doi.org/10.3390/ijms23126373

APA

Kuznetsova, A. A., Fedorova, O. S., & Kuznetsov, N. A. (2022). Structural and Molecular Kinetic Features of Activities of DNA Polymerases. International Journal of Molecular Sciences, 23(12), [6373]. https://doi.org/10.3390/ijms23126373

Vancouver

Kuznetsova AA, Fedorova OS, Kuznetsov NA. Structural and Molecular Kinetic Features of Activities of DNA Polymerases. International Journal of Molecular Sciences. 2022 июнь 1;23(12):6373. doi: 10.3390/ijms23126373

Author

Kuznetsova, Aleksandra A. ; Fedorova, Olga S. ; Kuznetsov, Nikita A. / Structural and Molecular Kinetic Features of Activities of DNA Polymerases. в: International Journal of Molecular Sciences. 2022 ; Том 23, № 12.

BibTeX

@article{9e820eb7b4f54f1aa67c2d1d890a6dfd,
title = "Structural and Molecular Kinetic Features of Activities of DNA Polymerases",
abstract = "DNA polymerases catalyze DNA synthesis during the replication, repair, and recombination of DNA. Based on phylogenetic analysis and primary protein sequences, DNA polymerases have been categorized into seven families: A, B, C, D, X, Y, and RT. This review presents generalized data on the catalytic mechanism of action of DNA polymerases. The structural features of different DNA polymerase families are described in detail. The discussion highlights the kinetics and conformational dynamics of DNA polymerases from all known polymerase families during DNA synthesis.",
keywords = "catalytic mechanism, DNA polymerase, kinetics, protein–DNA interaction, structural family, DNA/chemistry, DNA-Directed DNA Polymerase/metabolism, DNA Repair, Humans, DNA Replication, Kinetics, Phylogeny",
author = "Kuznetsova, {Aleksandra A.} and Fedorova, {Olga S.} and Kuznetsov, {Nikita A.}",
note = "Funding Information: This work was supported by the Ministry of Science and Higher Education of the Russian Federation, agreement No. 075-15-2021-1085. Publisher Copyright: {\textcopyright} 2022 by the authors. Licensee MDPI, Basel, Switzerland.",
year = "2022",
month = jun,
day = "1",
doi = "10.3390/ijms23126373",
language = "English",
volume = "23",
journal = "International Journal of Molecular Sciences",
issn = "1661-6596",
publisher = "Multidisciplinary Digital Publishing Institute (MDPI)",
number = "12",

}

RIS

TY - JOUR

T1 - Structural and Molecular Kinetic Features of Activities of DNA Polymerases

AU - Kuznetsova, Aleksandra A.

AU - Fedorova, Olga S.

AU - Kuznetsov, Nikita A.

N1 - Funding Information: This work was supported by the Ministry of Science and Higher Education of the Russian Federation, agreement No. 075-15-2021-1085. Publisher Copyright: © 2022 by the authors. Licensee MDPI, Basel, Switzerland.

PY - 2022/6/1

Y1 - 2022/6/1

N2 - DNA polymerases catalyze DNA synthesis during the replication, repair, and recombination of DNA. Based on phylogenetic analysis and primary protein sequences, DNA polymerases have been categorized into seven families: A, B, C, D, X, Y, and RT. This review presents generalized data on the catalytic mechanism of action of DNA polymerases. The structural features of different DNA polymerase families are described in detail. The discussion highlights the kinetics and conformational dynamics of DNA polymerases from all known polymerase families during DNA synthesis.

AB - DNA polymerases catalyze DNA synthesis during the replication, repair, and recombination of DNA. Based on phylogenetic analysis and primary protein sequences, DNA polymerases have been categorized into seven families: A, B, C, D, X, Y, and RT. This review presents generalized data on the catalytic mechanism of action of DNA polymerases. The structural features of different DNA polymerase families are described in detail. The discussion highlights the kinetics and conformational dynamics of DNA polymerases from all known polymerase families during DNA synthesis.

KW - catalytic mechanism

KW - DNA polymerase

KW - kinetics

KW - protein–DNA interaction

KW - structural family

KW - DNA/chemistry

KW - DNA-Directed DNA Polymerase/metabolism

KW - DNA Repair

KW - Humans

KW - DNA Replication

KW - Kinetics

KW - Phylogeny

UR - http://www.scopus.com/inward/record.url?scp=85131315396&partnerID=8YFLogxK

UR - https://www.mendeley.com/catalogue/31c72349-4c6f-3e32-88cc-c3af62330a2f/

U2 - 10.3390/ijms23126373

DO - 10.3390/ijms23126373

M3 - Review article

C2 - 35742812

AN - SCOPUS:85131315396

VL - 23

JO - International Journal of Molecular Sciences

JF - International Journal of Molecular Sciences

SN - 1661-6596

IS - 12

M1 - 6373

ER -

ID: 36438217