Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование
Specifics of anaphase chromatid segregation in Drosophila melanogaster mitotic mutants. / Lebedeva, L. I.; Fedorova, S. A.; Omelyanchuk, L. V.
в: Russian Journal of Genetics, Том 44, № 8, 08.2008, стр. 919-927.Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование
}
TY - JOUR
T1 - Specifics of anaphase chromatid segregation in Drosophila melanogaster mitotic mutants
AU - Lebedeva, L. I.
AU - Fedorova, S. A.
AU - Omelyanchuk, L. V.
PY - 2008/8
Y1 - 2008/8
N2 - Anaphase chromatid segregation defects (CSDs) were quantitatively and qualitatively studied in neural ganglion cells of third-instar larvae of several control wild type Drosophila melanogaster strains and four strains with mutations of the aar v158 , ff3, mast v40 , and CycB 2g cell cycle genes. A linear specificity was observed for the CSD frequency, type, determination, and correction probability. The probability of anaphase CSD correction was close to unity in the control strains and lower in the mutant strains. The lower correction probability in the mutant strains was explained in the context of two findings, that the mutations induced the CSDs that were atypical of the wild type strains and were potentially uncorrectable in anaphase and that the mutations negatively affected the relative anaphase time in mitosis.
AB - Anaphase chromatid segregation defects (CSDs) were quantitatively and qualitatively studied in neural ganglion cells of third-instar larvae of several control wild type Drosophila melanogaster strains and four strains with mutations of the aar v158 , ff3, mast v40 , and CycB 2g cell cycle genes. A linear specificity was observed for the CSD frequency, type, determination, and correction probability. The probability of anaphase CSD correction was close to unity in the control strains and lower in the mutant strains. The lower correction probability in the mutant strains was explained in the context of two findings, that the mutations induced the CSDs that were atypical of the wild type strains and were potentially uncorrectable in anaphase and that the mutations negatively affected the relative anaphase time in mitosis.
UR - http://www.scopus.com/inward/record.url?scp=50449103254&partnerID=8YFLogxK
U2 - 10.1134/S102279540808005X
DO - 10.1134/S102279540808005X
M3 - Article
AN - SCOPUS:50449103254
VL - 44
SP - 919
EP - 927
JO - Russian Journal of Genetics
JF - Russian Journal of Genetics
SN - 1022-7954
IS - 8
ER -
ID: 25439984