Результаты исследований: Научные публикации в периодических изданиях › обзорная статья › Рецензирование
Solid/gas biocatalysis. / Kulishova, L. M.; Zharkov, D. O.
в: Biochemistry (Moscow), Том 82, № 2, 01.02.2017, стр. 95-105.Результаты исследований: Научные публикации в периодических изданиях › обзорная статья › Рецензирование
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TY - JOUR
T1 - Solid/gas biocatalysis
AU - Kulishova, L. M.
AU - Zharkov, D. O.
PY - 2017/2/1
Y1 - 2017/2/1
N2 - Solid/gas biocatalysis is a nontraditional reaction system that employs the ability of some enzymes, being in the solid state, to catalyze reactions of substrates in the gas phase. Manipulation of the reaction parameters (temperature and pressure) in the solid/gas system allows precise control over the thermodynamic activity of water and substrate and creation of a controlled microenvironment for the enzyme, making it an appropriate model for enzymology studies. Owing to such advantages as high stability of dry enzymes and cofactors and easy fractionation of gas mixtures, solid/gas biotechnology has already found several industrial applications. Here we review key thermodynamic factors affecting the properties of enzymes, including their activity and stability, in a solid/gas system. Examples of promising enzymes and microorganisms for development and improvement of solid/gas biocatalytic technologies in organic synthesis, biosensors, and green chemistry are discussed.
AB - Solid/gas biocatalysis is a nontraditional reaction system that employs the ability of some enzymes, being in the solid state, to catalyze reactions of substrates in the gas phase. Manipulation of the reaction parameters (temperature and pressure) in the solid/gas system allows precise control over the thermodynamic activity of water and substrate and creation of a controlled microenvironment for the enzyme, making it an appropriate model for enzymology studies. Owing to such advantages as high stability of dry enzymes and cofactors and easy fractionation of gas mixtures, solid/gas biotechnology has already found several industrial applications. Here we review key thermodynamic factors affecting the properties of enzymes, including their activity and stability, in a solid/gas system. Examples of promising enzymes and microorganisms for development and improvement of solid/gas biocatalytic technologies in organic synthesis, biosensors, and green chemistry are discussed.
KW - alcohol dehydrogenases
KW - dehalogenases
KW - esterases
KW - immobilized enzymes
KW - lipases
KW - lyophilized enzymes
KW - protein hydration
KW - solid/gas biocatalysis
UR - http://www.scopus.com/inward/record.url?scp=85013218766&partnerID=8YFLogxK
U2 - 10.1134/S000629791702002X
DO - 10.1134/S000629791702002X
M3 - Review article
C2 - 28320294
AN - SCOPUS:85013218766
VL - 82
SP - 95
EP - 105
JO - Biochemistry (Moscow)
JF - Biochemistry (Moscow)
SN - 0006-2979
IS - 2
ER -
ID: 8672736