Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование
Quantifying the effects of quadrupolar sinks : Via 15N relaxation dynamics in metronidazoles hyperpolarized via SABRE-SHEATH. / Birchall, Jonathan R.; Kabir, Mohammad S.H.; Salnikov, Oleg G. и др.
в: Chemical Communications, Том 56, № 64, 18.08.2020, стр. 9098-9101.Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование
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TY - JOUR
T1 - Quantifying the effects of quadrupolar sinks
T2 - Via 15N relaxation dynamics in metronidazoles hyperpolarized via SABRE-SHEATH
AU - Birchall, Jonathan R.
AU - Kabir, Mohammad S.H.
AU - Salnikov, Oleg G.
AU - Chukanov, Nikita V.
AU - Svyatova, Alexandra
AU - Kovtunov, Kirill V.
AU - Koptyug, Igor V.
AU - Gelovani, Juri G.
AU - Goodson, Boyd M.
AU - Pham, Wellington
AU - Chekmenev, Eduard Y.
PY - 2020/8/18
Y1 - 2020/8/18
N2 - 15N spin-lattice relaxation dynamics in metronidazole- 15N 3 and metronidazole- 15N 2 isotopologues are studied for rational design of 15N-enriched biomolecules for signal amplification by reversible exchange in microtesla fields. 15N relaxation dynamics mapping reveals the deleterious effects of interactions with the polarization transfer catalyst and a quadrupolar 14N nucleus within the spin-relayed 15N- 15N network.
AB - 15N spin-lattice relaxation dynamics in metronidazole- 15N 3 and metronidazole- 15N 2 isotopologues are studied for rational design of 15N-enriched biomolecules for signal amplification by reversible exchange in microtesla fields. 15N relaxation dynamics mapping reveals the deleterious effects of interactions with the polarization transfer catalyst and a quadrupolar 14N nucleus within the spin-relayed 15N- 15N network.
KW - REVERSIBLE EXCHANGE
KW - SIGNAL AMPLIFICATION
KW - CATALYSTS
KW - MRI
UR - http://www.scopus.com/inward/record.url?scp=85089359035&partnerID=8YFLogxK
U2 - 10.1039/d0cc03994b
DO - 10.1039/d0cc03994b
M3 - Article
C2 - 32661534
AN - SCOPUS:85089359035
VL - 56
SP - 9098
EP - 9101
JO - Chemical Communications
JF - Chemical Communications
SN - 1359-7345
IS - 64
ER -
ID: 25291289