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Noncoding RNAs in the Regulation of Pluripotency and Reprogramming. / Sherstyuk, Vladimir V.; Medvedev, Sergey P.; Zakian, Suren M.

в: Stem Cell Reviews and Reports, Том 14, № 1, 01.02.2018, стр. 58-70.

Результаты исследований: Научные публикации в периодических изданияхобзорная статьяРецензирование

Harvard

Sherstyuk, VV, Medvedev, SP & Zakian, SM 2018, 'Noncoding RNAs in the Regulation of Pluripotency and Reprogramming', Stem Cell Reviews and Reports, Том. 14, № 1, стр. 58-70. https://doi.org/10.1007/s12015-017-9782-9

APA

Sherstyuk, V. V., Medvedev, S. P., & Zakian, S. M. (2018). Noncoding RNAs in the Regulation of Pluripotency and Reprogramming. Stem Cell Reviews and Reports, 14(1), 58-70. https://doi.org/10.1007/s12015-017-9782-9

Vancouver

Sherstyuk VV, Medvedev SP, Zakian SM. Noncoding RNAs in the Regulation of Pluripotency and Reprogramming. Stem Cell Reviews and Reports. 2018 февр. 1;14(1):58-70. doi: 10.1007/s12015-017-9782-9

Author

Sherstyuk, Vladimir V. ; Medvedev, Sergey P. ; Zakian, Suren M. / Noncoding RNAs in the Regulation of Pluripotency and Reprogramming. в: Stem Cell Reviews and Reports. 2018 ; Том 14, № 1. стр. 58-70.

BibTeX

@article{7e1711c5c1af4299ad0964c5bc9ec082,
title = "Noncoding RNAs in the Regulation of Pluripotency and Reprogramming",
abstract = "Pluripotent stem cells have great potential for developmental biology and regenerative medicine. Embryonic stem cells, which are obtained from blastocysts, and induced pluripotent stem cells, which are generated by the reprogramming of somatic cells, are two main types of pluripotent cells. It is important to understand the regulatory network that controls the pluripotency state and reprogramming process. Various types of noncoding RNAs (ncRNAs) have emerged as substantial components of regulatory networks. The most studied class of ncRNAs in the context of pluripotency and reprogramming is microRNAs (miRNAs). In addition to canonical microRNAs, other types of small RNAs with miRNA-like function are expressed in PSCs. Another class of ncRNAs, long ncRNAs, are also involved in pluripotency and reprogramming regulation. Thousands of ncRNAs have been annotated to date, and a significant number of the molecules do not have known function. In this review, we briefly summarized recent advances in this field and described existing genome-editing approaches to study ncRNA functions.",
keywords = "CRISPR/Cas9, Genome editing, Long noncoding RNA, MicroRNA, Noncoding RNA, Pluripotency, Pluripotent stem cells, Reprogramming, GROUND-STATE, WIDE IDENTIFICATION, DNA METHYLATION, MESENCHYMAL TRANSITION, MIR-200 FAMILY, SMALL NUCLEOLAR RNA, TRANSCRIPTIONAL REPRESSORS, MIRNA EXPRESSION, EMBRYONIC STEM-CELLS, PROFILING REVEALS",
author = "Sherstyuk, {Vladimir V.} and Medvedev, {Sergey P.} and Zakian, {Suren M.}",
note = "Publisher Copyright: {\textcopyright} 2017, Springer Science+Business Media, LLC, part of Springer Nature.",
year = "2018",
month = feb,
day = "1",
doi = "10.1007/s12015-017-9782-9",
language = "English",
volume = "14",
pages = "58--70",
journal = "Stem Cell Reviews and Reports",
issn = "2629-3269",
publisher = "Springer Nature",
number = "1",

}

RIS

TY - JOUR

T1 - Noncoding RNAs in the Regulation of Pluripotency and Reprogramming

AU - Sherstyuk, Vladimir V.

AU - Medvedev, Sergey P.

AU - Zakian, Suren M.

N1 - Publisher Copyright: © 2017, Springer Science+Business Media, LLC, part of Springer Nature.

PY - 2018/2/1

Y1 - 2018/2/1

N2 - Pluripotent stem cells have great potential for developmental biology and regenerative medicine. Embryonic stem cells, which are obtained from blastocysts, and induced pluripotent stem cells, which are generated by the reprogramming of somatic cells, are two main types of pluripotent cells. It is important to understand the regulatory network that controls the pluripotency state and reprogramming process. Various types of noncoding RNAs (ncRNAs) have emerged as substantial components of regulatory networks. The most studied class of ncRNAs in the context of pluripotency and reprogramming is microRNAs (miRNAs). In addition to canonical microRNAs, other types of small RNAs with miRNA-like function are expressed in PSCs. Another class of ncRNAs, long ncRNAs, are also involved in pluripotency and reprogramming regulation. Thousands of ncRNAs have been annotated to date, and a significant number of the molecules do not have known function. In this review, we briefly summarized recent advances in this field and described existing genome-editing approaches to study ncRNA functions.

AB - Pluripotent stem cells have great potential for developmental biology and regenerative medicine. Embryonic stem cells, which are obtained from blastocysts, and induced pluripotent stem cells, which are generated by the reprogramming of somatic cells, are two main types of pluripotent cells. It is important to understand the regulatory network that controls the pluripotency state and reprogramming process. Various types of noncoding RNAs (ncRNAs) have emerged as substantial components of regulatory networks. The most studied class of ncRNAs in the context of pluripotency and reprogramming is microRNAs (miRNAs). In addition to canonical microRNAs, other types of small RNAs with miRNA-like function are expressed in PSCs. Another class of ncRNAs, long ncRNAs, are also involved in pluripotency and reprogramming regulation. Thousands of ncRNAs have been annotated to date, and a significant number of the molecules do not have known function. In this review, we briefly summarized recent advances in this field and described existing genome-editing approaches to study ncRNA functions.

KW - CRISPR/Cas9

KW - Genome editing

KW - Long noncoding RNA

KW - MicroRNA

KW - Noncoding RNA

KW - Pluripotency

KW - Pluripotent stem cells

KW - Reprogramming

KW - GROUND-STATE

KW - WIDE IDENTIFICATION

KW - DNA METHYLATION

KW - MESENCHYMAL TRANSITION

KW - MIR-200 FAMILY

KW - SMALL NUCLEOLAR RNA

KW - TRANSCRIPTIONAL REPRESSORS

KW - MIRNA EXPRESSION

KW - EMBRYONIC STEM-CELLS

KW - PROFILING REVEALS

UR - http://www.scopus.com/inward/record.url?scp=85034025880&partnerID=8YFLogxK

U2 - 10.1007/s12015-017-9782-9

DO - 10.1007/s12015-017-9782-9

M3 - Review article

C2 - 29143182

AN - SCOPUS:85034025880

VL - 14

SP - 58

EP - 70

JO - Stem Cell Reviews and Reports

JF - Stem Cell Reviews and Reports

SN - 2629-3269

IS - 1

ER -

ID: 8798081