Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование
No Catalyst Added Hydrogen Peroxide Oxidation of Dextran : An Environmentally Friendly Route to Multifunctional Polymers. / Pronina, Ekaterina V.; Vorotnikov, Yuri A.; Pozmogova, Tatiana N. и др.
в: ACS Sustainable Chemistry and Engineering, Том 8, № 13, 06.04.2020, стр. 5371-5379.Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование
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TY - JOUR
T1 - No Catalyst Added Hydrogen Peroxide Oxidation of Dextran
T2 - An Environmentally Friendly Route to Multifunctional Polymers
AU - Pronina, Ekaterina V.
AU - Vorotnikov, Yuri A.
AU - Pozmogova, Tatiana N.
AU - Solovieva, Anastasiya O.
AU - Miroshnichenko, Svetlana M.
AU - Plyusnin, Pavel E.
AU - Pishchur, Denis P.
AU - Eltsov, Ilia V.
AU - Edeleva, Mariya V.
AU - Shestopalov, Michael A.
AU - Efremova, Olga A.
N1 - Publisher Copyright: © 2020 American Chemical Society. Copyright: Copyright 2020 Elsevier B.V., All rights reserved.
PY - 2020/4/6
Y1 - 2020/4/6
N2 - The paper demonstrates a "greener" oxidation of dextran polymer of various molecular masses, the component of many industrially and pharmaceutically important materials, by aqueous H2O2 in a no catalyst added setting that produced a multifunctional oxidized dextran. Specifically, on the top of common functional groups (hydroxo, carbonyl, and carboxylic acids), the freshly peroxide oxidized dextran had also a significant number of peroxo-groups, which endowed the polymer with significant cytotoxic properties, as demonstrated on a larynx carcinoma cell line. We also have shown that the peroxo-groups could be easily removed in an alkaline media to yield nontoxic oxidized dextran polymers.
AB - The paper demonstrates a "greener" oxidation of dextran polymer of various molecular masses, the component of many industrially and pharmaceutically important materials, by aqueous H2O2 in a no catalyst added setting that produced a multifunctional oxidized dextran. Specifically, on the top of common functional groups (hydroxo, carbonyl, and carboxylic acids), the freshly peroxide oxidized dextran had also a significant number of peroxo-groups, which endowed the polymer with significant cytotoxic properties, as demonstrated on a larynx carcinoma cell line. We also have shown that the peroxo-groups could be easily removed in an alkaline media to yield nontoxic oxidized dextran polymers.
KW - Cytotoxicity
KW - Dextran polysaccharide
KW - Functional groups
KW - Green oxidation
KW - Hydrogen peroxide
UR - http://www.scopus.com/inward/record.url?scp=85083812766&partnerID=8YFLogxK
U2 - 10.1021/acssuschemeng.0c01030
DO - 10.1021/acssuschemeng.0c01030
M3 - Article
AN - SCOPUS:85083812766
VL - 8
SP - 5371
EP - 5379
JO - ACS Sustainable Chemistry and Engineering
JF - ACS Sustainable Chemistry and Engineering
SN - 2168-0485
IS - 13
ER -
ID: 24160308