Результаты исследований: Научные публикации в периодических изданиях › обзорная статья › Рецензирование
Modern approaches to modification of bile acids for the synthesis of compounds possessing valuable physicochemical and biological properties. / Popadyuk, Irina I.; Salomatina, Oksana V.; Salakhutdinov, Nariman F.
в: Russian Chemical Reviews, Том 86, № 5, 2017, стр. 388-443.Результаты исследований: Научные публикации в периодических изданиях › обзорная статья › Рецензирование
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TY - JOUR
T1 - Modern approaches to modification of bile acids for the synthesis of compounds possessing valuable physicochemical and biological properties
AU - Popadyuk, Irina I.
AU - Salomatina, Oksana V.
AU - Salakhutdinov, Nariman F.
PY - 2017
Y1 - 2017
N2 - Data published in the period from 2000 to 2015 on chemical transformations of the major human bile acids (cholic, chenodeoxycholic, deoxycholic and lithocholic acids) and ursodeoxycholic acid are integrated and described systematically. Characteristic features of their structures, biosynthesis, main sources and biological functions are considered. The data on chemical transformations of the indicated bile acids include reactions involving modifications of the side chain or the steroid nucleus. The biological activities and applications of these derivatives are surveyed in brief. The bibliography includes 227 references.
AB - Data published in the period from 2000 to 2015 on chemical transformations of the major human bile acids (cholic, chenodeoxycholic, deoxycholic and lithocholic acids) and ursodeoxycholic acid are integrated and described systematically. Characteristic features of their structures, biosynthesis, main sources and biological functions are considered. The data on chemical transformations of the indicated bile acids include reactions involving modifications of the side chain or the steroid nucleus. The biological activities and applications of these derivatives are surveyed in brief. The bibliography includes 227 references.
KW - RECEPTOR 1 GP-BAR1
KW - PALLADIUM-CATALYZED AMINATION
KW - CARBONIC-ANHYDRASE INHIBITORS
KW - RING-CLOSING METATHESIS
KW - O-IODOXYBENZOIC ACID
KW - FARNESOID-X-RECEPTOR
KW - ALPHA-AMINO-ACIDS
KW - CHOLIC-ACID
KW - URSODEOXYCHOLIC ACID
KW - IN-VITRO
UR - http://www.scopus.com/inward/record.url?scp=85020265352&partnerID=8YFLogxK
U2 - 10.1070/RCR4683
DO - 10.1070/RCR4683
M3 - Review article
AN - SCOPUS:85020265352
VL - 86
SP - 388
EP - 443
JO - Russian Chemical Reviews
JF - Russian Chemical Reviews
SN - 0036-021X
IS - 5
ER -
ID: 9560787