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Luminescent Ag(I) scorpionates based on tris(2-pyridyl)phosphine oxide : Synthesis and cytotoxic activity evaluation. / Artem'ev, Alexander V.; Eremina, Julia A.; Lider, Elizaveta V. и др.
в: Polyhedron, Том 138, 14.12.2017, стр. 218-224.Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование
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TY - JOUR
T1 - Luminescent Ag(I) scorpionates based on tris(2-pyridyl)phosphine oxide
T2 - Synthesis and cytotoxic activity evaluation
AU - Artem'ev, Alexander V.
AU - Eremina, Julia A.
AU - Lider, Elizaveta V.
AU - Antonova, Olga V.
AU - Vorontsova, Elena V.
AU - Bagryanskaya, Irina Yu
N1 - Publisher Copyright: © 2017 Elsevier Ltd
PY - 2017/12/14
Y1 - 2017/12/14
N2 - First representatives of Ag(I) scorpionates bearing tris(2-pyridyl)phosphine oxide (Py3P[dbnd]O), viz. [Ag(Py3P[dbnd]O)(PPh3)]BF4 (1) and [Ag(Py3P[dbnd]O)(PPh3)]ClO4 (2), have been synthesized and structurally characterized. X-ray diffraction analysis reveals that the silver atom of 1 is coordinated by Py3P[dbnd]O and Ph3P ligands in N,N′,N″-tripodal and P-monodentate fashions, respectively. The both complexes exhibit significant cytotoxic activity (IC50 being from 11 to 14 μM) screened in vitro against human larynx carcinoma (Hep-2) cell lines. The luminescent proprieties of the prepared scorpionates are also discussed.
AB - First representatives of Ag(I) scorpionates bearing tris(2-pyridyl)phosphine oxide (Py3P[dbnd]O), viz. [Ag(Py3P[dbnd]O)(PPh3)]BF4 (1) and [Ag(Py3P[dbnd]O)(PPh3)]ClO4 (2), have been synthesized and structurally characterized. X-ray diffraction analysis reveals that the silver atom of 1 is coordinated by Py3P[dbnd]O and Ph3P ligands in N,N′,N″-tripodal and P-monodentate fashions, respectively. The both complexes exhibit significant cytotoxic activity (IC50 being from 11 to 14 μM) screened in vitro against human larynx carcinoma (Hep-2) cell lines. The luminescent proprieties of the prepared scorpionates are also discussed.
KW - Cytotoxic activity
KW - Luminescence
KW - Scorpionates
KW - Silver
KW - Tris(2-pyridyl)phosphine oxide
KW - ANTIMICROBIAL PROPERTIES
KW - ADDUCTS
KW - COPPER
KW - UNSUPPORTED SILVER-GERMANIUM
KW - LIGANDS
KW - CARBONYL
KW - CATALYZED CARBENE INSERTION
KW - TRIS(PYRAZOLYL)BORATE
KW - DERIVATIVES
KW - ETHYLENE COMPLEXES
UR - http://www.scopus.com/inward/record.url?scp=85031506873&partnerID=8YFLogxK
U2 - 10.1016/j.poly.2017.09.041
DO - 10.1016/j.poly.2017.09.041
M3 - Article
AN - SCOPUS:85031506873
VL - 138
SP - 218
EP - 224
JO - Polyhedron
JF - Polyhedron
SN - 0277-5387
ER -
ID: 9079229