Результаты исследований: Научные публикации в периодических изданиях › обзорная статья › Рецензирование
Hyperpolarized NMR Spectroscopy : d-DNP, PHIP, and SABRE Techniques. / Kovtunov, Kirill V.; Pokochueva, Ekaterina V.; Salnikov, Oleg G. и др.
в: Chemistry - An Asian Journal, Том 13, № 15, 06.08.2018, стр. 1857-1871.Результаты исследований: Научные публикации в периодических изданиях › обзорная статья › Рецензирование
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TY - JOUR
T1 - Hyperpolarized NMR Spectroscopy
T2 - d-DNP, PHIP, and SABRE Techniques
AU - Kovtunov, Kirill V.
AU - Pokochueva, Ekaterina V.
AU - Salnikov, Oleg G.
AU - Cousin, Samuel F.
AU - Kurzbach, Dennis
AU - Vuichoud, Basile
AU - Jannin, Sami
AU - Chekmenev, Eduard Y.
AU - Goodson, Boyd M.
AU - Barskiy, Danila A.
AU - Koptyug, Igor V.
N1 - Publisher Copyright: © 2018 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim
PY - 2018/8/6
Y1 - 2018/8/6
N2 - The intensity of NMR signals can be enhanced by several orders of magnitude by using various techniques for the hyperpolarization of different molecules. Such approaches can overcome the main sensitivity challenges facing modern NMR/magnetic resonance imaging (MRI) techniques, whilst hyperpolarized fluids can also be used in a variety of applications in material science and biomedicine. This Focus Review considers the fundamentals of the preparation of hyperpolarized liquids and gases by using dissolution dynamic nuclear polarization (d-DNP) and parahydrogen-based techniques, such as signal amplification by reversible exchange (SABRE) and parahydrogen-induced polarization (PHIP), in both heterogeneous and homogeneous processes. The various new aspects in the formation and utilization of hyperpolarized fluids, along with the possibility of observing NMR signal enhancement, are described.
AB - The intensity of NMR signals can be enhanced by several orders of magnitude by using various techniques for the hyperpolarization of different molecules. Such approaches can overcome the main sensitivity challenges facing modern NMR/magnetic resonance imaging (MRI) techniques, whilst hyperpolarized fluids can also be used in a variety of applications in material science and biomedicine. This Focus Review considers the fundamentals of the preparation of hyperpolarized liquids and gases by using dissolution dynamic nuclear polarization (d-DNP) and parahydrogen-based techniques, such as signal amplification by reversible exchange (SABRE) and parahydrogen-induced polarization (PHIP), in both heterogeneous and homogeneous processes. The various new aspects in the formation and utilization of hyperpolarized fluids, along with the possibility of observing NMR signal enhancement, are described.
KW - biological activity
KW - contrast agents
KW - hyperpolarization
KW - imaging agents
KW - NMR spectroscopy
UR - http://www.scopus.com/inward/record.url?scp=85050603145&partnerID=8YFLogxK
U2 - 10.1002/asia.201800551
DO - 10.1002/asia.201800551
M3 - Review article
C2 - 29790649
AN - SCOPUS:85050603145
VL - 13
SP - 1857
EP - 1871
JO - Chemistry - An Asian Journal
JF - Chemistry - An Asian Journal
SN - 1861-4728
IS - 15
ER -
ID: 15962399