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Hyperpolarized NMR Spectroscopy : d-DNP, PHIP, and SABRE Techniques. / Kovtunov, Kirill V.; Pokochueva, Ekaterina V.; Salnikov, Oleg G. et al.

In: Chemistry - An Asian Journal, Vol. 13, No. 15, 06.08.2018, p. 1857-1871.

Research output: Contribution to journal › Review article › peer-review

Harvard

Kovtunov, KV, Pokochueva, EV, Salnikov, OG, Cousin, SF, Kurzbach, D, Vuichoud, B, Jannin, S, Chekmenev, EY, Goodson, BM, Barskiy, DA & Koptyug, IV 2018, 'Hyperpolarized NMR Spectroscopy: d-DNP, PHIP, and SABRE Techniques', Chemistry - An Asian Journal, vol. 13, no. 15, pp. 1857-1871. https://doi.org/10.1002/asia.201800551

APA

Kovtunov, K. V., Pokochueva, E. V., Salnikov, O. G., Cousin, S. F., Kurzbach, D., Vuichoud, B., Jannin, S., Chekmenev, E. Y., Goodson, B. M., Barskiy, D. A., & Koptyug, I. V. (2018). Hyperpolarized NMR Spectroscopy: d-DNP, PHIP, and SABRE Techniques. Chemistry - An Asian Journal, 13(15), 1857-1871. https://doi.org/10.1002/asia.201800551

Vancouver

Kovtunov KV, Pokochueva EV, Salnikov OG, Cousin SF, Kurzbach D, Vuichoud B et al. Hyperpolarized NMR Spectroscopy: d-DNP, PHIP, and SABRE Techniques. Chemistry - An Asian Journal. 2018 Aug 6;13(15):1857-1871. Epub 2018 May 23. doi: 10.1002/asia.201800551

Author

Kovtunov, Kirill V. ; Pokochueva, Ekaterina V. ; Salnikov, Oleg G. et al. / Hyperpolarized NMR Spectroscopy : d-DNP, PHIP, and SABRE Techniques. In: Chemistry - An Asian Journal. 2018 ; Vol. 13, No. 15. pp. 1857-1871.

BibTeX

@article{b0e547d200e6404b99a66162d60e00d3,

title = "Hyperpolarized NMR Spectroscopy: d-DNP, PHIP, and SABRE Techniques",

abstract = "The intensity of NMR signals can be enhanced by several orders of magnitude by using various techniques for the hyperpolarization of different molecules. Such approaches can overcome the main sensitivity challenges facing modern NMR/magnetic resonance imaging (MRI) techniques, whilst hyperpolarized fluids can also be used in a variety of applications in material science and biomedicine. This Focus Review considers the fundamentals of the preparation of hyperpolarized liquids and gases by using dissolution dynamic nuclear polarization (d-DNP) and parahydrogen-based techniques, such as signal amplification by reversible exchange (SABRE) and parahydrogen-induced polarization (PHIP), in both heterogeneous and homogeneous processes. The various new aspects in the formation and utilization of hyperpolarized fluids, along with the possibility of observing NMR signal enhancement, are described.",

keywords = "biological activity, contrast agents, hyperpolarization, imaging agents, NMR spectroscopy",

author = "Kovtunov, {Kirill V.} and Pokochueva, {Ekaterina V.} and Salnikov, {Oleg G.} and Cousin, {Samuel F.} and Dennis Kurzbach and Basile Vuichoud and Sami Jannin and Chekmenev, {Eduard Y.} and Goodson, {Boyd M.} and Barskiy, {Danila A.} and Koptyug, {Igor V.}",

note = "Publisher Copyright: {\textcopyright} 2018 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim",

year = "2018",

month = aug,

day = "6",

doi = "10.1002/asia.201800551",

language = "English",

volume = "13",

pages = "1857--1871",

journal = "Chemistry - An Asian Journal",

issn = "1861-4728",

publisher = "John Wiley and Sons Ltd",

number = "15",

}

RIS

TY - JOUR

T1 - Hyperpolarized NMR Spectroscopy

T2 - d-DNP, PHIP, and SABRE Techniques

AU - Kovtunov, Kirill V.

AU - Pokochueva, Ekaterina V.

AU - Salnikov, Oleg G.

AU - Cousin, Samuel F.

AU - Kurzbach, Dennis

AU - Vuichoud, Basile

AU - Jannin, Sami

AU - Chekmenev, Eduard Y.

AU - Goodson, Boyd M.

AU - Barskiy, Danila A.

AU - Koptyug, Igor V.

PY - 2018/8/6

Y1 - 2018/8/6

N2 - The intensity of NMR signals can be enhanced by several orders of magnitude by using various techniques for the hyperpolarization of different molecules. Such approaches can overcome the main sensitivity challenges facing modern NMR/magnetic resonance imaging (MRI) techniques, whilst hyperpolarized fluids can also be used in a variety of applications in material science and biomedicine. This Focus Review considers the fundamentals of the preparation of hyperpolarized liquids and gases by using dissolution dynamic nuclear polarization (d-DNP) and parahydrogen-based techniques, such as signal amplification by reversible exchange (SABRE) and parahydrogen-induced polarization (PHIP), in both heterogeneous and homogeneous processes. The various new aspects in the formation and utilization of hyperpolarized fluids, along with the possibility of observing NMR signal enhancement, are described.

AB - The intensity of NMR signals can be enhanced by several orders of magnitude by using various techniques for the hyperpolarization of different molecules. Such approaches can overcome the main sensitivity challenges facing modern NMR/magnetic resonance imaging (MRI) techniques, whilst hyperpolarized fluids can also be used in a variety of applications in material science and biomedicine. This Focus Review considers the fundamentals of the preparation of hyperpolarized liquids and gases by using dissolution dynamic nuclear polarization (d-DNP) and parahydrogen-based techniques, such as signal amplification by reversible exchange (SABRE) and parahydrogen-induced polarization (PHIP), in both heterogeneous and homogeneous processes. The various new aspects in the formation and utilization of hyperpolarized fluids, along with the possibility of observing NMR signal enhancement, are described.

KW - biological activity

KW - contrast agents

KW - hyperpolarization

KW - imaging agents

KW - NMR spectroscopy

UR - http://www.scopus.com/inward/record.url?scp=85050603145&partnerID=8YFLogxK

U2 - 10.1002/asia.201800551

DO - 10.1002/asia.201800551

M3 - Review article

C2 - 29790649

AN - SCOPUS:85050603145

VL - 13

SP - 1857

EP - 1871

JO - Chemistry - An Asian Journal

JF - Chemistry - An Asian Journal

SN - 1861-4728

IS - 15

ER -

ID: 15962399