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Elemental Boron-10 Nanoparticles Synthesized by Laser Fragmentation for Boron Neutron Capture Therapy: In Vitro Experiments. / Касатова, Анна Исмагиловна; Кузьмина, Ксения Сергеевна; Касатов, Дмитрий Александрович и др.

в: Bulletin of the Lebedev Physics Institute, Том 52, № 2, 02.2025, стр. 95-102.

Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование

Harvard

Касатова, АИ, Кузьмина, КС, Касатов, ДА, Бармина, ЕВ, Айыыжы, КО, Котельникова, ПА, Григорьева, МС, Петруня, ДС, Завьялов, ЕЛ, Таскаев, СЮ, Деев, СМ & Завестовская, ИН 2025, 'Elemental Boron-10 Nanoparticles Synthesized by Laser Fragmentation for Boron Neutron Capture Therapy: In Vitro Experiments', Bulletin of the Lebedev Physics Institute, Том. 52, № 2, стр. 95-102. https://doi.org/10.3103/S1068335624602541

APA

Касатова, А. И., Кузьмина, К. С., Касатов, Д. А., Бармина, Е. В., Айыыжы, К. О., Котельникова, П. А., Григорьева, М. С., Петруня, Д. С., Завьялов, Е. Л., Таскаев, С. Ю., Деев, С. М., & Завестовская, И. Н. (2025). Elemental Boron-10 Nanoparticles Synthesized by Laser Fragmentation for Boron Neutron Capture Therapy: In Vitro Experiments. Bulletin of the Lebedev Physics Institute, 52(2), 95-102. https://doi.org/10.3103/S1068335624602541

Vancouver

Касатова АИ, Кузьмина КС, Касатов ДА, Бармина ЕВ, Айыыжы КО, Котельникова ПА и др. Elemental Boron-10 Nanoparticles Synthesized by Laser Fragmentation for Boron Neutron Capture Therapy: In Vitro Experiments. Bulletin of the Lebedev Physics Institute. 2025 февр.;52(2):95-102. doi: 10.3103/S1068335624602541

Author

Касатова, Анна Исмагиловна ; Кузьмина, Ксения Сергеевна ; Касатов, Дмитрий Александрович и др. / Elemental Boron-10 Nanoparticles Synthesized by Laser Fragmentation for Boron Neutron Capture Therapy: In Vitro Experiments. в: Bulletin of the Lebedev Physics Institute. 2025 ; Том 52, № 2. стр. 95-102.

BibTeX

@article{101542d5dbf54dfe88e2158ac2e10202,
title = "Elemental Boron-10 Nanoparticles Synthesized by Laser Fragmentation for Boron Neutron Capture Therapy: In Vitro Experiments",
abstract = "Elemental boron-10 nanoparticles synthesized by laser fragmentation of micropowder in isopropanol are used for the first time as a boron-containing agent for boron neutron capture therapy. The study is conducted on human cell cultures U87, BT474, and BJ-5TA. It is found that these nanoparticles are nontoxic to all three cell cultures at boron-10 concentrations required for successful boron neutron capture therapy. The cell cultures are pre-incubated with nanoparticles and then irradiated for 30 min with a beam of epithermal neutrons generated by the VITA accelerator source (BINP SB RAS, Novosibirsk). Using in vitro study results (MTT assay and clonogenic analysis), an enhancement of the therapeutic effect of boron neutron capture therapy is observed.",
keywords = "BORON NEUTRON CAPTURE THERAPY, ELEMENTAL BORON NANOPARTICLES, LASER FRAGMENTATION, CELL CULTURES",
author = "Касатова, {Анна Исмагиловна} and Кузьмина, {Ксения Сергеевна} and Касатов, {Дмитрий Александрович} and Бармина, {Екатерина Владимировна} and Айыыжы, {Кудер Омакович} and Котельникова, {Полина Александровна} and Григорьева, {Мария Сергеевна} and Петруня, {Дмитрий Сергеевич} and Завьялов, {Евгений Леонидович} and Таскаев, {Сергей Юрьевич} and Деев, {Сергей Михайлович} and Завестовская, {Ирина Николаевна}",
note = "Elemental Boron-10 Nanoparticles Synthesized by Laser Fragmentation for Boron Neutron Capture Therapy: In Vitro Experiments / A. I. Kasatova, K. S. Kuzmina, D. A. Kasatov [et al.] // Bulletin of the Lebedev Physics Institute. – 2025. – Vol. 52. - No. 2. – P. 95-102. – DOI 10.3103/S1068335624602541. – EDN MGMBCG. The work was supported by the Russian Science Foundation (grant no. 24-62-00018, Advanced Combined Technologies of Neutron Capture Therapy Program).",
year = "2025",
month = feb,
doi = "10.3103/S1068335624602541",
language = "English",
volume = "52",
pages = "95--102",
journal = "Bulletin of the Lebedev Physics Institute",
issn = "1068-3356",
publisher = "Springer",
number = "2",

}

RIS

TY - JOUR

T1 - Elemental Boron-10 Nanoparticles Synthesized by Laser Fragmentation for Boron Neutron Capture Therapy: In Vitro Experiments

AU - Касатова, Анна Исмагиловна

AU - Кузьмина, Ксения Сергеевна

AU - Касатов, Дмитрий Александрович

AU - Бармина, Екатерина Владимировна

AU - Айыыжы, Кудер Омакович

AU - Котельникова, Полина Александровна

AU - Григорьева, Мария Сергеевна

AU - Петруня, Дмитрий Сергеевич

AU - Завьялов, Евгений Леонидович

AU - Таскаев, Сергей Юрьевич

AU - Деев, Сергей Михайлович

AU - Завестовская, Ирина Николаевна

N1 - Elemental Boron-10 Nanoparticles Synthesized by Laser Fragmentation for Boron Neutron Capture Therapy: In Vitro Experiments / A. I. Kasatova, K. S. Kuzmina, D. A. Kasatov [et al.] // Bulletin of the Lebedev Physics Institute. – 2025. – Vol. 52. - No. 2. – P. 95-102. – DOI 10.3103/S1068335624602541. – EDN MGMBCG. The work was supported by the Russian Science Foundation (grant no. 24-62-00018, Advanced Combined Technologies of Neutron Capture Therapy Program).

PY - 2025/2

Y1 - 2025/2

N2 - Elemental boron-10 nanoparticles synthesized by laser fragmentation of micropowder in isopropanol are used for the first time as a boron-containing agent for boron neutron capture therapy. The study is conducted on human cell cultures U87, BT474, and BJ-5TA. It is found that these nanoparticles are nontoxic to all three cell cultures at boron-10 concentrations required for successful boron neutron capture therapy. The cell cultures are pre-incubated with nanoparticles and then irradiated for 30 min with a beam of epithermal neutrons generated by the VITA accelerator source (BINP SB RAS, Novosibirsk). Using in vitro study results (MTT assay and clonogenic analysis), an enhancement of the therapeutic effect of boron neutron capture therapy is observed.

AB - Elemental boron-10 nanoparticles synthesized by laser fragmentation of micropowder in isopropanol are used for the first time as a boron-containing agent for boron neutron capture therapy. The study is conducted on human cell cultures U87, BT474, and BJ-5TA. It is found that these nanoparticles are nontoxic to all three cell cultures at boron-10 concentrations required for successful boron neutron capture therapy. The cell cultures are pre-incubated with nanoparticles and then irradiated for 30 min with a beam of epithermal neutrons generated by the VITA accelerator source (BINP SB RAS, Novosibirsk). Using in vitro study results (MTT assay and clonogenic analysis), an enhancement of the therapeutic effect of boron neutron capture therapy is observed.

KW - BORON NEUTRON CAPTURE THERAPY

KW - ELEMENTAL BORON NANOPARTICLES

KW - LASER FRAGMENTATION

KW - CELL CULTURES

UR - https://elibrary.ru/item.asp?id=80616024

U2 - 10.3103/S1068335624602541

DO - 10.3103/S1068335624602541

M3 - Article

VL - 52

SP - 95

EP - 102

JO - Bulletin of the Lebedev Physics Institute

JF - Bulletin of the Lebedev Physics Institute

SN - 1068-3356

IS - 2

ER -

ID: 72826690