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Development and Validation of a Method for Determination of a New Effective Inhibitor of Influenza Virus H1N1 in Blood Plasma. / Sokolova, A. S.; Yarovaya, O. I.; Nefedov, A. A. и др.

в: Pharmaceutical Chemistry Journal, Том 51, № 12, 03.2018, стр. 1102-1105.

Результаты исследований: Научные публикации в периодических изданияхстатьяРецензирование

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Sokolova, A. S. ; Yarovaya, O. I. ; Nefedov, A. A. и др. / Development and Validation of a Method for Determination of a New Effective Inhibitor of Influenza Virus H1N1 in Blood Plasma. в: Pharmaceutical Chemistry Journal. 2018 ; Том 51, № 12. стр. 1102-1105.

BibTeX

@article{d07bbcfdb4ef4be8ad4780d00c16b1c1,
title = "Development and Validation of a Method for Determination of a New Effective Inhibitor of Influenza Virus H1N1 in Blood Plasma",
abstract = "A new GC-MS method for determining an antiviral agent (camphecin) in blood plasma was developed. Sample preparation consisted of precipitating proteins using MeOH. The method was validated for selectivity, calibration curve, accuracy, precision, limit of quantitation, carryover, and stability. The analytical range was 0.1 – 2 μg/mL. The method could be used for pharmacokinetic studies.",
keywords = "camphecin, GC-MS, plasma, validation, A VIRUSES, ANTIVIRAL ACTIVITY, DERIVATIVES",
author = "Sokolova, {A. S.} and Yarovaya, {O. I.} and Nefedov, {A. A.} and Salakhutdinov, {N. F.}",
year = "2018",
month = mar,
doi = "10.1007/s11094-018-1748-y",
language = "English",
volume = "51",
pages = "1102--1105",
journal = "Pharmaceutical Chemistry Journal",
issn = "0091-150X",
publisher = "Springer New York",
number = "12",

}

RIS

TY - JOUR

T1 - Development and Validation of a Method for Determination of a New Effective Inhibitor of Influenza Virus H1N1 in Blood Plasma

AU - Sokolova, A. S.

AU - Yarovaya, O. I.

AU - Nefedov, A. A.

AU - Salakhutdinov, N. F.

PY - 2018/3

Y1 - 2018/3

N2 - A new GC-MS method for determining an antiviral agent (camphecin) in blood plasma was developed. Sample preparation consisted of precipitating proteins using MeOH. The method was validated for selectivity, calibration curve, accuracy, precision, limit of quantitation, carryover, and stability. The analytical range was 0.1 – 2 μg/mL. The method could be used for pharmacokinetic studies.

AB - A new GC-MS method for determining an antiviral agent (camphecin) in blood plasma was developed. Sample preparation consisted of precipitating proteins using MeOH. The method was validated for selectivity, calibration curve, accuracy, precision, limit of quantitation, carryover, and stability. The analytical range was 0.1 – 2 μg/mL. The method could be used for pharmacokinetic studies.

KW - camphecin

KW - GC-MS

KW - plasma

KW - validation

KW - A VIRUSES

KW - ANTIVIRAL ACTIVITY

KW - DERIVATIVES

UR - http://www.scopus.com/inward/record.url?scp=85043467305&partnerID=8YFLogxK

U2 - 10.1007/s11094-018-1748-y

DO - 10.1007/s11094-018-1748-y

M3 - Article

AN - SCOPUS:85043467305

VL - 51

SP - 1102

EP - 1105

JO - Pharmaceutical Chemistry Journal

JF - Pharmaceutical Chemistry Journal

SN - 0091-150X

IS - 12

ER -

ID: 10415770