Research output: Contribution to journal › Article › peer-review
Development and Validation of a Method for Determination of a New Effective Inhibitor of Influenza Virus H1N1 in Blood Plasma. / Sokolova, A. S.; Yarovaya, O. I.; Nefedov, A. A. et al.
In: Pharmaceutical Chemistry Journal, Vol. 51, No. 12, 03.2018, p. 1102-1105.Research output: Contribution to journal › Article › peer-review
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TY - JOUR
T1 - Development and Validation of a Method for Determination of a New Effective Inhibitor of Influenza Virus H1N1 in Blood Plasma
AU - Sokolova, A. S.
AU - Yarovaya, O. I.
AU - Nefedov, A. A.
AU - Salakhutdinov, N. F.
PY - 2018/3
Y1 - 2018/3
N2 - A new GC-MS method for determining an antiviral agent (camphecin) in blood plasma was developed. Sample preparation consisted of precipitating proteins using MeOH. The method was validated for selectivity, calibration curve, accuracy, precision, limit of quantitation, carryover, and stability. The analytical range was 0.1 – 2 μg/mL. The method could be used for pharmacokinetic studies.
AB - A new GC-MS method for determining an antiviral agent (camphecin) in blood plasma was developed. Sample preparation consisted of precipitating proteins using MeOH. The method was validated for selectivity, calibration curve, accuracy, precision, limit of quantitation, carryover, and stability. The analytical range was 0.1 – 2 μg/mL. The method could be used for pharmacokinetic studies.
KW - camphecin
KW - GC-MS
KW - plasma
KW - validation
KW - A VIRUSES
KW - ANTIVIRAL ACTIVITY
KW - DERIVATIVES
UR - http://www.scopus.com/inward/record.url?scp=85043467305&partnerID=8YFLogxK
U2 - 10.1007/s11094-018-1748-y
DO - 10.1007/s11094-018-1748-y
M3 - Article
AN - SCOPUS:85043467305
VL - 51
SP - 1102
EP - 1105
JO - Pharmaceutical Chemistry Journal
JF - Pharmaceutical Chemistry Journal
SN - 0091-150X
IS - 12
ER -
ID: 10415770