Co-expression of membrane-bound TNF-alpha type 1 and 2 receptors differ in the subsets of immunocompetent cells

Standard

Co-expression of membrane-bound TNF-alpha type 1 and 2 receptors differ in the subsets of immunocompetent cells. / Sennikov, Sergey; Alshevskaya, Alina; Zhukova, Julia и др.

в: Immunology Letters, Том 207, 01.03.2019, стр. 1-5.

Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование

Harvard

Sennikov, S, Alshevskaya, A, Zhukova, J, Belomestnova, I, Karaulov, A, Evsegneeva, I & Lopatnikova, J 2019, 'Co-expression of membrane-bound TNF-alpha type 1 and 2 receptors differ in the subsets of immunocompetent cells', Immunology Letters, Том. 207, стр. 1-5. https://doi.org/10.1016/j.imlet.2019.01.005

APA

Sennikov, S., Alshevskaya, A., Zhukova, J., Belomestnova, I., Karaulov, A., Evsegneeva, I., & Lopatnikova, J. (2019). Co-expression of membrane-bound TNF-alpha type 1 and 2 receptors differ in the subsets of immunocompetent cells. Immunology Letters, 207, 1-5. https://doi.org/10.1016/j.imlet.2019.01.005

Vancouver

Sennikov S, Alshevskaya A, Zhukova J, Belomestnova I, Karaulov A, Evsegneeva I и др. Co-expression of membrane-bound TNF-alpha type 1 and 2 receptors differ in the subsets of immunocompetent cells. Immunology Letters. 2019 март 1;207:1-5. doi: 10.1016/j.imlet.2019.01.005

Author

Sennikov, Sergey ; Alshevskaya, Alina ; Zhukova, Julia и др. / Co-expression of membrane-bound TNF-alpha type 1 and 2 receptors differ in the subsets of immunocompetent cells. в: Immunology Letters. 2019 ; Том 207. стр. 1-5.

BibTeX

@article{ffbbc991bb8745f68664ed24d16959d0,

title = "Co-expression of membrane-bound TNF-alpha type 1 and 2 receptors differ in the subsets of immunocompetent cells",

abstract = "The immunoregulatory cytokine tumor necrosis factor α plays crucial roles in the pathogenesis of a broad spectrum of disorders. However, its effect may depend on the expression and co-expression of receptors on the target cell. The aim of the present study was to evaluate the expression levels of type 1 and 2 tumor necrosis factor α receptors (TNFR1/2) on individual cell subsets from peripheral blood of healthy volunteers. Flow cytometry analysis was used to study whole populations as well as subsets (T regulatory cells, T memory cells, cytotoxic T cells, T helper cells). Significant differences in the co-expression of TNFR1/2 were seen within subsets and total pools. Further studies are necessary to explore the implications of the observed differences in the modulation of tumor necrosis factor α function in health and pathology.",

keywords = "Cellular immunology, Cytokine receptors expression, Immune regulation, EXPRESSION",

author = "Sergey Sennikov and Alina Alshevskaya and Julia Zhukova and Irina Belomestnova and Aleksander Karaulov and Irina Evsegneeva and Julia Lopatnikova",

year = "2019",

month = mar,

day = "1",

doi = "10.1016/j.imlet.2019.01.005",

language = "English",

volume = "207",

pages = "1--5",

journal = "Immunology Letters",

issn = "0165-2478",

publisher = "Elsevier",

}

RIS

TY - JOUR

T1 - Co-expression of membrane-bound TNF-alpha type 1 and 2 receptors differ in the subsets of immunocompetent cells

AU - Sennikov, Sergey

AU - Alshevskaya, Alina

AU - Zhukova, Julia

AU - Belomestnova, Irina

AU - Karaulov, Aleksander

AU - Evsegneeva, Irina

AU - Lopatnikova, Julia

PY - 2019/3/1

Y1 - 2019/3/1

N2 - The immunoregulatory cytokine tumor necrosis factor α plays crucial roles in the pathogenesis of a broad spectrum of disorders. However, its effect may depend on the expression and co-expression of receptors on the target cell. The aim of the present study was to evaluate the expression levels of type 1 and 2 tumor necrosis factor α receptors (TNFR1/2) on individual cell subsets from peripheral blood of healthy volunteers. Flow cytometry analysis was used to study whole populations as well as subsets (T regulatory cells, T memory cells, cytotoxic T cells, T helper cells). Significant differences in the co-expression of TNFR1/2 were seen within subsets and total pools. Further studies are necessary to explore the implications of the observed differences in the modulation of tumor necrosis factor α function in health and pathology.

AB - The immunoregulatory cytokine tumor necrosis factor α plays crucial roles in the pathogenesis of a broad spectrum of disorders. However, its effect may depend on the expression and co-expression of receptors on the target cell. The aim of the present study was to evaluate the expression levels of type 1 and 2 tumor necrosis factor α receptors (TNFR1/2) on individual cell subsets from peripheral blood of healthy volunteers. Flow cytometry analysis was used to study whole populations as well as subsets (T regulatory cells, T memory cells, cytotoxic T cells, T helper cells). Significant differences in the co-expression of TNFR1/2 were seen within subsets and total pools. Further studies are necessary to explore the implications of the observed differences in the modulation of tumor necrosis factor α function in health and pathology.

KW - Cellular immunology

KW - Cytokine receptors expression

KW - Immune regulation

KW - EXPRESSION

UR - http://www.scopus.com/inward/record.url?scp=85060220346&partnerID=8YFLogxK

U2 - 10.1016/j.imlet.2019.01.005

DO - 10.1016/j.imlet.2019.01.005

M3 - Article

C2 - 30639514

AN - SCOPUS:85060220346

VL - 207

SP - 1

EP - 5

JO - Immunology Letters

JF - Immunology Letters

SN - 0165-2478

ER -

ID: 18296730