Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование
Chemical Reaction Monitoring using Zero-Field Nuclear Magnetic Resonance Enables Study of Heterogeneous Samples in Metal Containers. / Burueva, Dudari B.; Eills, James; Blanchard, John W. и др.
в: Angewandte Chemie - International Edition, Том 59, № 39, 21.09.2020, стр. 17026-17032.Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование
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TY - JOUR
T1 - Chemical Reaction Monitoring using Zero-Field Nuclear Magnetic Resonance Enables Study of Heterogeneous Samples in Metal Containers
AU - Burueva, Dudari B.
AU - Eills, James
AU - Blanchard, John W.
AU - Garcon, Antoine
AU - Picazo-Frutos, Román
AU - Kovtunov, Kirill V.
AU - Koptyug, Igor V.
AU - Budker, Dmitry
N1 - Publisher Copyright: © 2020 The Authors. Published by Wiley-VCH Verlag GmbH & Co. KGaA Copyright: Copyright 2020 Elsevier B.V., All rights reserved.
PY - 2020/9/21
Y1 - 2020/9/21
N2 - We demonstrate that heterogeneous/biphasic chemical reactions can be monitored with high spectroscopic resolution using zero-field nuclear magnetic resonance spectroscopy. This is possible because magnetic susceptibility broadening is negligible at ultralow magnetic fields. We show the two-step hydrogenation of dimethyl acetylenedicarboxylate with para-enriched hydrogen gas in conventional glass NMR tubes, as well as in a titanium tube. The low frequency zero-field NMR signals ensure that there is no significant signal attenuation arising from shielding by the electrically conductive sample container. This method paves the way for in situ monitoring of reactions in complex heterogeneous multiphase systems and in reactors made of conductive materials while maintaining resolution and chemical specificity.
AB - We demonstrate that heterogeneous/biphasic chemical reactions can be monitored with high spectroscopic resolution using zero-field nuclear magnetic resonance spectroscopy. This is possible because magnetic susceptibility broadening is negligible at ultralow magnetic fields. We show the two-step hydrogenation of dimethyl acetylenedicarboxylate with para-enriched hydrogen gas in conventional glass NMR tubes, as well as in a titanium tube. The low frequency zero-field NMR signals ensure that there is no significant signal attenuation arising from shielding by the electrically conductive sample container. This method paves the way for in situ monitoring of reactions in complex heterogeneous multiphase systems and in reactors made of conductive materials while maintaining resolution and chemical specificity.
KW - catalysis
KW - hyperpolarization
KW - NMR spectroscopy
KW - reaction monitoring
KW - zero-field
KW - PARA-HYDROGEN
KW - SPIN DYNAMICS
KW - NMR-SPECTROSCOPY
KW - PARAHYDROGEN
KW - FLOW
KW - KINETICS
KW - CHEMISTRY
KW - COUPLINGS
KW - CATIONIC RHODIUM COMPLEXES
KW - POLARIZATION TRANSFER
UR - http://www.scopus.com/inward/record.url?scp=85088515698&partnerID=8YFLogxK
U2 - 10.1002/anie.202006266
DO - 10.1002/anie.202006266
M3 - Article
C2 - 32510813
AN - SCOPUS:85088515698
VL - 59
SP - 17026
EP - 17032
JO - Angewandte Chemie - International Edition
JF - Angewandte Chemie - International Edition
SN - 1433-7851
IS - 39
ER -
ID: 24823035