TY - JOUR

T1 - Analysis of Phenotypic Manifestation of peanut Gene Expression Suppression by RNAi in Drosophila Oogenesis

AU - Akhmetova, K. A.

AU - Dorogova, C. N.

AU - Chesnokov, I. N.

AU - Fedorova, S. A.

PY - 2015/9/1

Y1 - 2015/9/1

N2 - The peanut gene functions in Drosophila melanogaster oogenesis were studied. It was demonstrated that the suppression of peanut expression by RNA interference in the ovary follicular cells results in the violation of oocyte polarization, anomalous cytokinesis in the chorion cells, and violation of the chromatin condensation in follicular cells. No oogenesis violations were observed in females with decreased peanut gene expression or an absence of the Pnut protein in the ovary generative cells. However, embryos produced by such females had a decreased survival rate caused by two death peaks.

AB - The peanut gene functions in Drosophila melanogaster oogenesis were studied. It was demonstrated that the suppression of peanut expression by RNA interference in the ovary follicular cells results in the violation of oocyte polarization, anomalous cytokinesis in the chorion cells, and violation of the chromatin condensation in follicular cells. No oogenesis violations were observed in females with decreased peanut gene expression or an absence of the Pnut protein in the ovary generative cells. However, embryos produced by such females had a decreased survival rate caused by two death peaks.

UR - http://www.scopus.com/inward/record.url?scp=84953345263&partnerID=8YFLogxK

U2 - 10.7868/s0016675815090027

DO - 10.7868/s0016675815090027

M3 - Article

C2 - 26606795

AN - SCOPUS:84953345263

VL - 51

SP - 991

EP - 999

JO - Генетика

JF - Генетика

SN - 0016-6758

IS - 9

ER -