Analysis of Phenotypic Manifestation of peanut Gene Expression Suppression by RNAi in Drosophila Oogenesis. / Akhmetova, K. A.; Dorogova, C. N.; Chesnokov, I. N. et al.
In: Genetika, Vol. 51, No. 9, 01.09.2015, p. 991-999.Research output: Contribution to journal › Article › peer-review
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TY - JOUR
T1 - Analysis of Phenotypic Manifestation of peanut Gene Expression Suppression by RNAi in Drosophila Oogenesis
AU - Akhmetova, K. A.
AU - Dorogova, C. N.
AU - Chesnokov, I. N.
AU - Fedorova, S. A.
PY - 2015/9/1
Y1 - 2015/9/1
N2 - The peanut gene functions in Drosophila melanogaster oogenesis were studied. It was demonstrated that the suppression of peanut expression by RNA interference in the ovary follicular cells results in the violation of oocyte polarization, anomalous cytokinesis in the chorion cells, and violation of the chromatin condensation in follicular cells. No oogenesis violations were observed in females with decreased peanut gene expression or an absence of the Pnut protein in the ovary generative cells. However, embryos produced by such females had a decreased survival rate caused by two death peaks.
AB - The peanut gene functions in Drosophila melanogaster oogenesis were studied. It was demonstrated that the suppression of peanut expression by RNA interference in the ovary follicular cells results in the violation of oocyte polarization, anomalous cytokinesis in the chorion cells, and violation of the chromatin condensation in follicular cells. No oogenesis violations were observed in females with decreased peanut gene expression or an absence of the Pnut protein in the ovary generative cells. However, embryos produced by such females had a decreased survival rate caused by two death peaks.
UR - http://www.scopus.com/inward/record.url?scp=84953345263&partnerID=8YFLogxK
U2 - 10.7868/s0016675815090027
DO - 10.7868/s0016675815090027
M3 - Article
C2 - 26606795
AN - SCOPUS:84953345263
VL - 51
SP - 991
EP - 999
JO - Генетика
JF - Генетика
SN - 0016-6758
IS - 9
ER -
ID: 25439424