Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование
A Monolithic Column with a Sorbent Based on 1-Vinyl-1,2,4-Triazole for Hydrophilic HPLC. / Patrushev, Yu V.; Sotnikova, Yu S.; Sidel’nikov, V. N.
в: Protection of Metals and Physical Chemistry of Surfaces, Том 56, № 1, 01.2020, стр. 49-53.Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование
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TY - JOUR
T1 - A Monolithic Column with a Sorbent Based on 1-Vinyl-1,2,4-Triazole for Hydrophilic HPLC
AU - Patrushev, Yu V.
AU - Sotnikova, Yu S.
AU - Sidel’nikov, V. N.
PY - 2020/1
Y1 - 2020/1
N2 - Abstract: A monolithic chromatographic column for HPLC with a sorbent based on 1-vinyl-1,2,4-triazole has been prepared for the first time. It has been shown that, depending on the composition of the mobile phase (acetonitrile/water ratio), this column is able to operate in the modes of both reverse phase chromatography and hydrophilic chromatography. The dependences of the retention factor on the volume fraction of acetonitrile in the mobile phase have been studied for substances of acidic and basic nature. An example of the separation of the components of the pharmaceutical product Askofen-P on the prepared column has been provided.
AB - Abstract: A monolithic chromatographic column for HPLC with a sorbent based on 1-vinyl-1,2,4-triazole has been prepared for the first time. It has been shown that, depending on the composition of the mobile phase (acetonitrile/water ratio), this column is able to operate in the modes of both reverse phase chromatography and hydrophilic chromatography. The dependences of the retention factor on the volume fraction of acetonitrile in the mobile phase have been studied for substances of acidic and basic nature. An example of the separation of the components of the pharmaceutical product Askofen-P on the prepared column has been provided.
KW - 1-vinyl-1,2,4-triazole
KW - HPLC
KW - hydrophilic interaction chromatography
KW - monolithic columns
KW - porous polymers
KW - ROD COLUMNS
KW - 4-triazole
KW - ACID
KW - CAPILLARY COLUMNS
KW - 2
KW - 1-vinyl-1
KW - POLYMER
KW - SEPARATION
KW - SELECTIVITY
KW - INTERACTION CHROMATOGRAPHY
UR - http://www.scopus.com/inward/record.url?scp=85083177067&partnerID=8YFLogxK
U2 - 10.1134/S2070205119060248
DO - 10.1134/S2070205119060248
M3 - Article
AN - SCOPUS:85083177067
VL - 56
SP - 49
EP - 53
JO - Protection of Metals and Physical Chemistry of Surfaces
JF - Protection of Metals and Physical Chemistry of Surfaces
SN - 2070-2051
IS - 1
ER -
ID: 24093841