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Unusual seeding effect in the liquid-assisted high-pressure polymorphism of chlorpropamide. / Zakharov, B. A.; Goryainov, S. V.; Boldyreva, E. V.

In: CrystEngComm, Vol. 18, No. 29, 2016, p. 5423-5428.

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Zakharov BA, Goryainov SV, Boldyreva EV. Unusual seeding effect in the liquid-assisted high-pressure polymorphism of chlorpropamide. CrystEngComm. 2016;18(29):5423-5428. doi: 10.1039/c6ce00711b

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@article{a386e34369c147c180b18f5d251752d1,
title = "Unusual seeding effect in the liquid-assisted high-pressure polymorphism of chlorpropamide",
abstract = "When crystals of four polymorphs-a stable α-form and three metastable ones (β-, γ-, δ-forms)-are simultaneously present in a pressure cell, immersed in a 1:1 pentane-isopentane mixture, the least stable β-form recrystallises exclusively into the γ-form (if no δ-form seed is present) or concomitantly into the γ- and δ-forms (if a seed of the δ-form is present). However, the β-form never recrystallises to the stable α-form, even if the latter is also present as a potential seed.",
author = "Zakharov, {B. A.} and Goryainov, {S. V.} and Boldyreva, {E. V.}",
year = "2016",
doi = "10.1039/c6ce00711b",
language = "English",
volume = "18",
pages = "5423--5428",
journal = "CrystEngComm",
issn = "1466-8033",
publisher = "Royal Society of Chemistry",
number = "29",

}

RIS

TY - JOUR

T1 - Unusual seeding effect in the liquid-assisted high-pressure polymorphism of chlorpropamide

AU - Zakharov, B. A.

AU - Goryainov, S. V.

AU - Boldyreva, E. V.

PY - 2016

Y1 - 2016

N2 - When crystals of four polymorphs-a stable α-form and three metastable ones (β-, γ-, δ-forms)-are simultaneously present in a pressure cell, immersed in a 1:1 pentane-isopentane mixture, the least stable β-form recrystallises exclusively into the γ-form (if no δ-form seed is present) or concomitantly into the γ- and δ-forms (if a seed of the δ-form is present). However, the β-form never recrystallises to the stable α-form, even if the latter is also present as a potential seed.

AB - When crystals of four polymorphs-a stable α-form and three metastable ones (β-, γ-, δ-forms)-are simultaneously present in a pressure cell, immersed in a 1:1 pentane-isopentane mixture, the least stable β-form recrystallises exclusively into the γ-form (if no δ-form seed is present) or concomitantly into the γ- and δ-forms (if a seed of the δ-form is present). However, the β-form never recrystallises to the stable α-form, even if the latter is also present as a potential seed.

UR - http://www.scopus.com/inward/record.url?scp=84979688344&partnerID=8YFLogxK

U2 - 10.1039/c6ce00711b

DO - 10.1039/c6ce00711b

M3 - Article

AN - SCOPUS:84979688344

VL - 18

SP - 5423

EP - 5428

JO - CrystEngComm

JF - CrystEngComm

SN - 1466-8033

IS - 29

ER -

ID: 25461761