Research output: Contribution to journal › Article › peer-review
Unusual seeding effect in the liquid-assisted high-pressure polymorphism of chlorpropamide. / Zakharov, B. A.; Goryainov, S. V.; Boldyreva, E. V.
In: CrystEngComm, Vol. 18, No. 29, 2016, p. 5423-5428.Research output: Contribution to journal › Article › peer-review
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TY - JOUR
T1 - Unusual seeding effect in the liquid-assisted high-pressure polymorphism of chlorpropamide
AU - Zakharov, B. A.
AU - Goryainov, S. V.
AU - Boldyreva, E. V.
PY - 2016
Y1 - 2016
N2 - When crystals of four polymorphs-a stable α-form and three metastable ones (β-, γ-, δ-forms)-are simultaneously present in a pressure cell, immersed in a 1:1 pentane-isopentane mixture, the least stable β-form recrystallises exclusively into the γ-form (if no δ-form seed is present) or concomitantly into the γ- and δ-forms (if a seed of the δ-form is present). However, the β-form never recrystallises to the stable α-form, even if the latter is also present as a potential seed.
AB - When crystals of four polymorphs-a stable α-form and three metastable ones (β-, γ-, δ-forms)-are simultaneously present in a pressure cell, immersed in a 1:1 pentane-isopentane mixture, the least stable β-form recrystallises exclusively into the γ-form (if no δ-form seed is present) or concomitantly into the γ- and δ-forms (if a seed of the δ-form is present). However, the β-form never recrystallises to the stable α-form, even if the latter is also present as a potential seed.
UR - http://www.scopus.com/inward/record.url?scp=84979688344&partnerID=8YFLogxK
U2 - 10.1039/c6ce00711b
DO - 10.1039/c6ce00711b
M3 - Article
AN - SCOPUS:84979688344
VL - 18
SP - 5423
EP - 5428
JO - CrystEngComm
JF - CrystEngComm
SN - 1466-8033
IS - 29
ER -
ID: 25461761