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Understanding neurobehavioral genetics of zebrafish. / Cheresiz, Sergey V.; Volgin, Andrey D.; Kokorina Evsyukova, Alexandra et al.

In: Journal of Neurogenetics, Vol. 34, No. 2, 02.04.2020, p. 203-215.

Research output: Contribution to journal › Review article › peer-review

Harvard

Cheresiz, SV, Volgin, AD, Kokorina Evsyukova, A, Bashirzade, AAO, Demin, KA, de Abreu, MS, Amstislavskaya, TG & Kalueff, AV 2020, 'Understanding neurobehavioral genetics of zebrafish', Journal of Neurogenetics, vol. 34, no. 2, pp. 203-215. https://doi.org/10.1080/01677063.2019.1698565

APA

Cheresiz, S. V., Volgin, A. D., Kokorina Evsyukova, A., Bashirzade, A. A. O., Demin, K. A., de Abreu, M. S., Amstislavskaya, T. G., & Kalueff, A. V. (2020). Understanding neurobehavioral genetics of zebrafish. Journal of Neurogenetics, 34(2), 203-215. https://doi.org/10.1080/01677063.2019.1698565

Vancouver

Cheresiz SV, Volgin AD, Kokorina Evsyukova A, Bashirzade AAO, Demin KA, de Abreu MS et al. Understanding neurobehavioral genetics of zebrafish. Journal of Neurogenetics. 2020 Apr 2;34(2):203-215. doi: 10.1080/01677063.2019.1698565

Author

Cheresiz, Sergey V. ; Volgin, Andrey D. ; Kokorina Evsyukova, Alexandra et al. / Understanding neurobehavioral genetics of zebrafish. In: Journal of Neurogenetics. 2020 ; Vol. 34, No. 2. pp. 203-215.

BibTeX

@article{a1bc1aa969cb4206bdaa5cc1bc49ddd7,
title = "Understanding neurobehavioral genetics of zebrafish",
abstract = "Due to its fully sequenced genome, high genetic homology to humans, external fertilization, fast development, transparency of embryos, low cost and active reproduction, the zebrafish (Danio rerio) has become a novel promising model organism in biomedicine. Zebrafish are a useful tool in genetic and neuroscience research, including linking various genetic mutations to brain mechanisms using forward and reverse genetics. These approaches have produced novel models of rare genetic CNS disorders and common brain illnesses, such as addiction, aggression, anxiety and depression. Genetically modified zebrafish also foster neuroanatomical studies, manipulating neural circuits and linking them to different behaviors. Here, we discuss recent advances in neurogenetics of zebrafish, and evaluate their unique strengths, inherent limitations and the rapidly growing potential for elucidating the conserved roles of genes in neuropsychiatric disorders.",
keywords = "brain disorders, forward genetics, reverse genetics, transgenic methods, Zebrafish, DANIO-RERIO, TRANSGENIC ZEBRAFISH, NEURONAL-ACTIVITY, KNOCK-IN, DOUBLE-STRANDED-RNA, MICRORNA PATHWAY, MARIE-TOOTH DISEASE, ANIMAL-MODELS, HOMOLOGOUS RECOMBINATION, CYCLIN-DEPENDENT KINASE-5",
author = "Cheresiz, {Sergey V.} and Volgin, {Andrey D.} and {Kokorina Evsyukova}, Alexandra and Bashirzade, {Alim A.O.} and Demin, {Konstantin A.} and {de Abreu}, {Murilo S.} and Amstislavskaya, {Tamara G.} and Kalueff, {Allan V.}",
year = "2020",
month = apr,
day = "2",
doi = "10.1080/01677063.2019.1698565",
language = "English",
volume = "34",
pages = "203--215",
journal = "Journal of Neurogenetics",
issn = "0167-7063",
publisher = "Informa Healthcare",
number = "2",

}

RIS

TY - JOUR

T1 - Understanding neurobehavioral genetics of zebrafish

AU - Cheresiz, Sergey V.

AU - Volgin, Andrey D.

AU - Kokorina Evsyukova, Alexandra

AU - Bashirzade, Alim A.O.

AU - Demin, Konstantin A.

AU - de Abreu, Murilo S.

AU - Amstislavskaya, Tamara G.

AU - Kalueff, Allan V.

PY - 2020/4/2

Y1 - 2020/4/2

N2 - Due to its fully sequenced genome, high genetic homology to humans, external fertilization, fast development, transparency of embryos, low cost and active reproduction, the zebrafish (Danio rerio) has become a novel promising model organism in biomedicine. Zebrafish are a useful tool in genetic and neuroscience research, including linking various genetic mutations to brain mechanisms using forward and reverse genetics. These approaches have produced novel models of rare genetic CNS disorders and common brain illnesses, such as addiction, aggression, anxiety and depression. Genetically modified zebrafish also foster neuroanatomical studies, manipulating neural circuits and linking them to different behaviors. Here, we discuss recent advances in neurogenetics of zebrafish, and evaluate their unique strengths, inherent limitations and the rapidly growing potential for elucidating the conserved roles of genes in neuropsychiatric disorders.

AB - Due to its fully sequenced genome, high genetic homology to humans, external fertilization, fast development, transparency of embryos, low cost and active reproduction, the zebrafish (Danio rerio) has become a novel promising model organism in biomedicine. Zebrafish are a useful tool in genetic and neuroscience research, including linking various genetic mutations to brain mechanisms using forward and reverse genetics. These approaches have produced novel models of rare genetic CNS disorders and common brain illnesses, such as addiction, aggression, anxiety and depression. Genetically modified zebrafish also foster neuroanatomical studies, manipulating neural circuits and linking them to different behaviors. Here, we discuss recent advances in neurogenetics of zebrafish, and evaluate their unique strengths, inherent limitations and the rapidly growing potential for elucidating the conserved roles of genes in neuropsychiatric disorders.

KW - brain disorders

KW - forward genetics

KW - reverse genetics

KW - transgenic methods

KW - Zebrafish

KW - DANIO-RERIO

KW - TRANSGENIC ZEBRAFISH

KW - NEURONAL-ACTIVITY

KW - KNOCK-IN

KW - DOUBLE-STRANDED-RNA

KW - MICRORNA PATHWAY

KW - MARIE-TOOTH DISEASE

KW - ANIMAL-MODELS

KW - HOMOLOGOUS RECOMBINATION

KW - CYCLIN-DEPENDENT KINASE-5

UR - http://www.scopus.com/inward/record.url?scp=85077911137&partnerID=8YFLogxK

U2 - 10.1080/01677063.2019.1698565

DO - 10.1080/01677063.2019.1698565

M3 - Review article

C2 - 31902276

AN - SCOPUS:85077911137

VL - 34

SP - 203

EP - 215

JO - Journal of Neurogenetics

JF - Journal of Neurogenetics

SN - 0167-7063

IS - 2

ER -

ID: 23145105