Research output: Contribution to journal › Article › peer-review
Template-Assisted Assembly of DNA Nanostructures from Branched Oligonucleotides. / Fokina, A. A.; Poletaeva, Yu E.; Burakova, E. A. et al.
In: Russian Journal of Bioorganic Chemistry, Vol. 47, No. 3, 05.2021, p. 700-712.Research output: Contribution to journal › Article › peer-review
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TY - JOUR
T1 - Template-Assisted Assembly of DNA Nanostructures from Branched Oligonucleotides
AU - Fokina, A. A.
AU - Poletaeva, Yu E.
AU - Burakova, E. A.
AU - Bakulina, A. Yu
AU - Zatsepin, T. S.
AU - Ryabchikova, E. I.
AU - Stetsenko, D. A.
N1 - Funding Information: The work was supported by the Russian Foundation for Basic Research (grant nos. 16-03-01055 and 18-29-08062), and the Ministry of Science and Higher Education of the Russian Federation (Novosibirsk State University project FSUS-2020-0035). Publisher Copyright: © 2021, Pleiades Publishing, Ltd.
PY - 2021/5
Y1 - 2021/5
N2 - We have proposed previously a template-assisted method for 3D assembly of nucleic acid nanostructures. The method involved a branched oligonucleotide as a template and a building block, which incorporates non-nucleotidic linkers, in particular, branching foci connecting two or three oligonucleotide chains. In this work, we have attempted the synthesis of branched oligonucleotide templates for the assembly of a DNA tetrahedron and a DNA cube, a branched oligonucleotide building block (“starlet”), and studied the assembly of a DNA tetrahedron.
AB - We have proposed previously a template-assisted method for 3D assembly of nucleic acid nanostructures. The method involved a branched oligonucleotide as a template and a building block, which incorporates non-nucleotidic linkers, in particular, branching foci connecting two or three oligonucleotide chains. In this work, we have attempted the synthesis of branched oligonucleotide templates for the assembly of a DNA tetrahedron and a DNA cube, a branched oligonucleotide building block (“starlet”), and studied the assembly of a DNA tetrahedron.
KW - click chemistry
KW - DNA nanotechnology
KW - nucleic acid
KW - photolabile protecting group
KW - solid-phase synthesis
KW - strain-promoted azide-alkyne cycloaddition (SPAAC)
UR - http://www.scopus.com/inward/record.url?scp=85107623656&partnerID=8YFLogxK
U2 - 10.1134/S1068162021030067
DO - 10.1134/S1068162021030067
M3 - Article
AN - SCOPUS:85107623656
VL - 47
SP - 700
EP - 712
JO - Russian Journal of Bioorganic Chemistry
JF - Russian Journal of Bioorganic Chemistry
SN - 1068-1620
IS - 3
ER -
ID: 34055734