Research output: Contribution to journal › Article › peer-review
Synthesis of benzo[c][1,7]naphthyridine derivatives. / Shatsauskas, Anton L.; Saibulina, Elina R.; Gatilov, Yurii V. et al.
In: Chemistry of Heterocyclic Compounds, Vol. 55, No. 11, 01.11.2019, p. 1080-1086.Research output: Contribution to journal › Article › peer-review
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TY - JOUR
T1 - Synthesis of benzo[c][1,7]naphthyridine derivatives
AU - Shatsauskas, Anton L.
AU - Saibulina, Elina R.
AU - Gatilov, Yurii V.
AU - Kostyuchenko, Anastasia S.
AU - Fisyuk, Alexander S.
PY - 2019/11/1
Y1 - 2019/11/1
N2 - Reactivity of 2-methyl-6-phenylbenzo[c][1,7]naphthyridine in alkylation, oxidation, and electrophilic substitution reactions has been studied. The reaction of 2-methyl-6-phenylbenzo[c][1,7]naphthyridines with POCl3 yielded the previously unknown 4-chloro-2-methyl-6-phenylbenzo[c][1,7]naphthyridine. Its dehalogenation and substitution of halogen by nitrogen and sulfur nucleophiles were studied.
AB - Reactivity of 2-methyl-6-phenylbenzo[c][1,7]naphthyridine in alkylation, oxidation, and electrophilic substitution reactions has been studied. The reaction of 2-methyl-6-phenylbenzo[c][1,7]naphthyridines with POCl3 yielded the previously unknown 4-chloro-2-methyl-6-phenylbenzo[c][1,7]naphthyridine. Its dehalogenation and substitution of halogen by nitrogen and sulfur nucleophiles were studied.
KW - alkylation
KW - benzo[c][1,7]naphthyridine
KW - electrophilic substitution
KW - nucleophilic substitution
KW - oxidation
KW - reactivity
KW - MARINE NATURAL-PRODUCT
KW - CHEMISTRY
KW - ANTAGONISTS
KW - AAPTAMINE
KW - ALKALOIDS
UR - http://www.scopus.com/inward/record.url?scp=85076018018&partnerID=8YFLogxK
U2 - 10.1007/s10593-019-02581-8
DO - 10.1007/s10593-019-02581-8
M3 - Article
AN - SCOPUS:85076018018
VL - 55
SP - 1080
EP - 1086
JO - Chemistry of Heterocyclic Compounds
JF - Chemistry of Heterocyclic Compounds
SN - 0009-3122
IS - 11
ER -
ID: 22577205