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Stabilization of TiO2 sols dispersity at physiological conditions and decrease their cytotoxic properties. / Shikina, Nadezhda V.; Bessudnova, Elena V.; Ryabchikova, Elena I. et al.

In: Journal of Nanoscience and Nanotechnology, Vol. 17, No. 12, 12.2017, p. 9312-9321.

Research output: Contribution to journal › Article › peer-review

Harvard

Shikina, NV, Bessudnova, EV, Ryabchikova, EI, Levina, AS, Zarytova, VF & Ismagilov, ZR 2017, 'Stabilization of TiO2 sols dispersity at physiological conditions and decrease their cytotoxic properties', Journal of Nanoscience and Nanotechnology, vol. 17, no. 12, pp. 9312-9321. https://doi.org/10.1166/jnn.2017.13916

APA

Shikina, N. V., Bessudnova, E. V., Ryabchikova, E. I., Levina, A. S., Zarytova, V. F., & Ismagilov, Z. R. (2017). Stabilization of TiO2 sols dispersity at physiological conditions and decrease their cytotoxic properties. Journal of Nanoscience and Nanotechnology, 17(12), 9312-9321. https://doi.org/10.1166/jnn.2017.13916

Vancouver

Shikina NV, Bessudnova EV, Ryabchikova EI, Levina AS, Zarytova VF, Ismagilov ZR. Stabilization of TiO2 sols dispersity at physiological conditions and decrease their cytotoxic properties. Journal of Nanoscience and Nanotechnology. 2017 Dec;17(12):9312-9321. doi: 10.1166/jnn.2017.13916

Author

Shikina, Nadezhda V. ; Bessudnova, Elena V. ; Ryabchikova, Elena I. et al. / Stabilization of TiO2 sols dispersity at physiological conditions and decrease their cytotoxic properties. In: Journal of Nanoscience and Nanotechnology. 2017 ; Vol. 17, No. 12. pp. 9312-9321.

BibTeX

@article{248ae09912364cdb862f57d15c4dcc58,
title = "Stabilization of TiO2 sols dispersity at physiological conditions and decrease their cytotoxic properties",
abstract = "The effect of chemical nature of LiOH, NaOH, KOH and NH4OH electrolytes, surface modification of TiO2 particles with isopropyl glycidyl ether (IGE), mixing order of reactants, and dialysis conditions on the dispersion and cell damage of TiO2 sols at neutral pH has been studied. Investigation of TiO2 sols by a set of physicochemical methods (XRD, Raman spectroscopy, SAXS, AFM, TEM, and ζ-potential measurements) showed the highest dispersity of sols was reached by their neutralization with LiOH. Trypan blue staining and transmission electron microscopy of ultrathin cell sections were used to study in vitro the damaging effect in MDCK cell culture after its incubation with titanium dioxide nanoparticles. It was shown that the surface modification of TiO2 nanoparticles with IGE and phosphate groups diminished its toxic effect on the cells and prevented undesirable interaction of TiO2 with cell components.",
keywords = "Aggregation, Anatase, Damaging effect, MDCK cell, Nanoparticles, Titanium dioxide, PARTICLES, MDCK Cell, Damaging Effect, NANOMATERIALS, TOXICITY, NANOCOMPOSITES, Titanium Dioxide, CELL-CULTURE, MICE, TITANIUM-DIOXIDE NANOPARTICLES",
author = "Shikina, {Nadezhda V.} and Bessudnova, {Elena V.} and Ryabchikova, {Elena I.} and Levina, {Asya S.} and Zarytova, {Valentina F.} and Ismagilov, {Zinfer R.}",
year = "2017",
month = dec,
doi = "10.1166/jnn.2017.13916",
language = "English",
volume = "17",
pages = "9312--9321",
journal = "Journal of Nanoscience and Nanotechnology",
issn = "1533-4880",
publisher = "American Scientific Publishers",
number = "12",

}

RIS

TY - JOUR

T1 - Stabilization of TiO2 sols dispersity at physiological conditions and decrease their cytotoxic properties

AU - Shikina, Nadezhda V.

AU - Bessudnova, Elena V.

AU - Ryabchikova, Elena I.

AU - Levina, Asya S.

AU - Zarytova, Valentina F.

AU - Ismagilov, Zinfer R.

PY - 2017/12

Y1 - 2017/12

N2 - The effect of chemical nature of LiOH, NaOH, KOH and NH4OH electrolytes, surface modification of TiO2 particles with isopropyl glycidyl ether (IGE), mixing order of reactants, and dialysis conditions on the dispersion and cell damage of TiO2 sols at neutral pH has been studied. Investigation of TiO2 sols by a set of physicochemical methods (XRD, Raman spectroscopy, SAXS, AFM, TEM, and ζ-potential measurements) showed the highest dispersity of sols was reached by their neutralization with LiOH. Trypan blue staining and transmission electron microscopy of ultrathin cell sections were used to study in vitro the damaging effect in MDCK cell culture after its incubation with titanium dioxide nanoparticles. It was shown that the surface modification of TiO2 nanoparticles with IGE and phosphate groups diminished its toxic effect on the cells and prevented undesirable interaction of TiO2 with cell components.

AB - The effect of chemical nature of LiOH, NaOH, KOH and NH4OH electrolytes, surface modification of TiO2 particles with isopropyl glycidyl ether (IGE), mixing order of reactants, and dialysis conditions on the dispersion and cell damage of TiO2 sols at neutral pH has been studied. Investigation of TiO2 sols by a set of physicochemical methods (XRD, Raman spectroscopy, SAXS, AFM, TEM, and ζ-potential measurements) showed the highest dispersity of sols was reached by their neutralization with LiOH. Trypan blue staining and transmission electron microscopy of ultrathin cell sections were used to study in vitro the damaging effect in MDCK cell culture after its incubation with titanium dioxide nanoparticles. It was shown that the surface modification of TiO2 nanoparticles with IGE and phosphate groups diminished its toxic effect on the cells and prevented undesirable interaction of TiO2 with cell components.

KW - Aggregation

KW - Anatase

KW - Damaging effect

KW - MDCK cell

KW - Nanoparticles

KW - Titanium dioxide

KW - PARTICLES

KW - MDCK Cell

KW - Damaging Effect

KW - NANOMATERIALS

KW - TOXICITY

KW - NANOCOMPOSITES

KW - Titanium Dioxide

KW - CELL-CULTURE

KW - MICE

KW - TITANIUM-DIOXIDE NANOPARTICLES

UR - http://www.scopus.com/inward/record.url?scp=85030462486&partnerID=8YFLogxK

U2 - 10.1166/jnn.2017.13916

DO - 10.1166/jnn.2017.13916

M3 - Article

AN - SCOPUS:85030462486

VL - 17

SP - 9312

EP - 9321

JO - Journal of Nanoscience and Nanotechnology

JF - Journal of Nanoscience and Nanotechnology

SN - 1533-4880

IS - 12

ER -

ID: 8673342