Screening and characterization of cocrystal formation between betulin and terephthalic acid

Standard

Screening and characterization of cocrystal formation between betulin and terephthalic acid. / Mikhailovskaya, Anastasiya V.; Myz, Svetlana A.; Bulina, Natalia V. et al.

In: Materials Today: Proceedings, Vol. 25, 2019, p. 381-383.

Research output: Contribution to journal › Conference article › peer-review

Harvard

Mikhailovskaya, AV, Myz, SA, Bulina, NV, Gerasimov, KB, Kuznetsova, SA & Shakhtshneider, TP 2019, 'Screening and characterization of cocrystal formation between betulin and terephthalic acid', Materials Today: Proceedings, vol. 25, pp. 381-383. https://doi.org/10.1016/j.matpr.2019.12.096

APA

Mikhailovskaya, A. V., Myz, S. A., Bulina, N. V., Gerasimov, K. B., Kuznetsova, S. A., & Shakhtshneider, T. P. (2019). Screening and characterization of cocrystal formation between betulin and terephthalic acid. Materials Today: Proceedings, 25, 381-383. https://doi.org/10.1016/j.matpr.2019.12.096

Vancouver

Mikhailovskaya AV, Myz SA, Bulina NV, Gerasimov KB, Kuznetsova SA, Shakhtshneider TP. Screening and characterization of cocrystal formation between betulin and terephthalic acid. Materials Today: Proceedings. 2019;25:381-383. doi: 10.1016/j.matpr.2019.12.096

Author

Mikhailovskaya, Anastasiya V. ; Myz, Svetlana A. ; Bulina, Natalia V. et al. / Screening and characterization of cocrystal formation between betulin and terephthalic acid. In: Materials Today: Proceedings. 2019 ; Vol. 25. pp. 381-383.

BibTeX

@article{84855430ce5142608cb5a10488951c86,

title = "Screening and characterization of cocrystal formation between betulin and terephthalic acid",

abstract = "The pharmaceutical cocrystals are nowdays intensively studied due to the improvements of solubility, stability, processability, etc. of the drugs. In this work, the cocrystals of betulin with terephthalic acid as a coformer were prepared by liquid-assisted grinding method. The formation of cocrystals was confirmed by powder X-ray diffraction, IR spectroscopy and thermal analysis methods. HPLC analysis showed that in the case of betulin - terephthalic acid cocrystals, solubility of betulin was significantly improved compared to the initial betulin as well as betulin from cocrystals with aliphatic dicarboxylic acids which were earlier prepared.",

keywords = "Betulin, Co-grinding, Cocrystal, Solubility, Terephthalic acid",

author = "Mikhailovskaya, {Anastasiya V.} and Myz, {Svetlana A.} and Bulina, {Natalia V.} and Gerasimov, {Konstantin B.} and Kuznetsova, {Svetlana A.} and Shakhtshneider, {Tatyana P.}",

note = "Publisher Copyright: {\textcopyright} 2019 Elsevier Ltd. Copyright: Copyright 2020 Elsevier B.V., All rights reserved; 3rd All-Russian Conference, with International Participation Hot Topics of Solid State Chemistry : From New Ideas to New Materials, HTSSC 2019 ; Conference date: 01-10-2019 Through 05-10-2019",

year = "2019",

doi = "10.1016/j.matpr.2019.12.096",

language = "English",

volume = "25",

pages = "381--383",

journal = "Materials Today: Proceedings",

issn = "2214-7853",

publisher = "Elsevier Science B.V.",

}

RIS

TY - JOUR

T1 - Screening and characterization of cocrystal formation between betulin and terephthalic acid

AU - Mikhailovskaya, Anastasiya V.

AU - Myz, Svetlana A.

AU - Bulina, Natalia V.

AU - Gerasimov, Konstantin B.

AU - Kuznetsova, Svetlana A.

AU - Shakhtshneider, Tatyana P.

PY - 2019

Y1 - 2019

N2 - The pharmaceutical cocrystals are nowdays intensively studied due to the improvements of solubility, stability, processability, etc. of the drugs. In this work, the cocrystals of betulin with terephthalic acid as a coformer were prepared by liquid-assisted grinding method. The formation of cocrystals was confirmed by powder X-ray diffraction, IR spectroscopy and thermal analysis methods. HPLC analysis showed that in the case of betulin - terephthalic acid cocrystals, solubility of betulin was significantly improved compared to the initial betulin as well as betulin from cocrystals with aliphatic dicarboxylic acids which were earlier prepared.

AB - The pharmaceutical cocrystals are nowdays intensively studied due to the improvements of solubility, stability, processability, etc. of the drugs. In this work, the cocrystals of betulin with terephthalic acid as a coformer were prepared by liquid-assisted grinding method. The formation of cocrystals was confirmed by powder X-ray diffraction, IR spectroscopy and thermal analysis methods. HPLC analysis showed that in the case of betulin - terephthalic acid cocrystals, solubility of betulin was significantly improved compared to the initial betulin as well as betulin from cocrystals with aliphatic dicarboxylic acids which were earlier prepared.

KW - Betulin

KW - Co-grinding

KW - Cocrystal

KW - Solubility

KW - Terephthalic acid

UR - http://www.scopus.com/inward/record.url?scp=85086948314&partnerID=8YFLogxK

U2 - 10.1016/j.matpr.2019.12.096

DO - 10.1016/j.matpr.2019.12.096

M3 - Conference article

AN - SCOPUS:85086948314

VL - 25

SP - 381

EP - 383

JO - Materials Today: Proceedings

JF - Materials Today: Proceedings

SN - 2214-7853

T2 - 3rd All-Russian Conference, with International Participation Hot Topics of Solid State Chemistry : From New Ideas to New Materials, HTSSC 2019

Y2 - 1 October 2019 through 5 October 2019

ER -

ID: 26145269