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SABRE Hyperpolarization of Bipyridine Stabilized Ir-Complex at High, Low and Ultralow Magnetic Fields. / Pravdivtsev, Andrey N.

In: Zeitschrift fur Physikalische Chemie, Vol. 231, No. 3, 01.03.2017, p. 497-511.

Research output: Contribution to journal › Article › peer-review

Harvard

Pravdivtsev, AN 2017, 'SABRE Hyperpolarization of Bipyridine Stabilized Ir-Complex at High, Low and Ultralow Magnetic Fields', Zeitschrift fur Physikalische Chemie, vol. 231, no. 3, pp. 497-511. https://doi.org/10.1515/zpch-2016-0810

APA

Pravdivtsev, A. N. (2017). SABRE Hyperpolarization of Bipyridine Stabilized Ir-Complex at High, Low and Ultralow Magnetic Fields. Zeitschrift fur Physikalische Chemie, 231(3), 497-511. https://doi.org/10.1515/zpch-2016-0810

Vancouver

Pravdivtsev AN. SABRE Hyperpolarization of Bipyridine Stabilized Ir-Complex at High, Low and Ultralow Magnetic Fields. Zeitschrift fur Physikalische Chemie. 2017 Mar 1;231(3):497-511. doi: 10.1515/zpch-2016-0810

Author

Pravdivtsev, Andrey N. / SABRE Hyperpolarization of Bipyridine Stabilized Ir-Complex at High, Low and Ultralow Magnetic Fields. In: Zeitschrift fur Physikalische Chemie. 2017 ; Vol. 231, No. 3. pp. 497-511.

BibTeX

@article{f46d6101b27c4551998029581e151a5e,
title = "SABRE Hyperpolarization of Bipyridine Stabilized Ir-Complex at High, Low and Ultralow Magnetic Fields",
abstract = "A strong limitation of nuclear magnetic resonance is its low inherent sensitivity that can be overcome by using an appropriate hyperpolarization technique. Presently, dynamic nuclear polarization and spin-exchange optical pumping are the only hyperpolarization techniques that are used in applied medicine. However, both are relatively complex in use and expensive. Here we present a modification of the signal amplification by reversible exchange (SABRE) hyperpolarization method-SABRE on stabilized Ir-complexes. A stabilized Ir-complex (here we used bipyridine for stabilization) can be hyperpolarized in a wide range of magnetic fields from a few μT upto 10 T with 15N polarization of about 1-3%. Moreover, the investigated complex can be incorporated into biomolecules or other bulky molecules; in this situation exchange with para-hydrogen will allow one to continuously generate hyperpolarization.",
keywords = "bipyridine, NMR, para-hydrogen, SABRE, PARA-HYDROGEN, LEVEL ANTI-CROSSINGS, RESONANCE, SPIN HYPERPOLARIZATION, PARAHYDROGEN, POLARIZATION TRANSFER, CATALYSTS, SIGNAL AMPLIFICATION",
author = "Pravdivtsev, {Andrey N.}",
year = "2017",
month = mar,
day = "1",
doi = "10.1515/zpch-2016-0810",
language = "English",
volume = "231",
pages = "497--511",
journal = "Zeitschrift fur Physikalische Chemie",
issn = "0942-9352",
publisher = "Walter de Gruyter GmbH",
number = "3",

}

RIS

TY - JOUR

T1 - SABRE Hyperpolarization of Bipyridine Stabilized Ir-Complex at High, Low and Ultralow Magnetic Fields

AU - Pravdivtsev, Andrey N.

PY - 2017/3/1

Y1 - 2017/3/1

N2 - A strong limitation of nuclear magnetic resonance is its low inherent sensitivity that can be overcome by using an appropriate hyperpolarization technique. Presently, dynamic nuclear polarization and spin-exchange optical pumping are the only hyperpolarization techniques that are used in applied medicine. However, both are relatively complex in use and expensive. Here we present a modification of the signal amplification by reversible exchange (SABRE) hyperpolarization method-SABRE on stabilized Ir-complexes. A stabilized Ir-complex (here we used bipyridine for stabilization) can be hyperpolarized in a wide range of magnetic fields from a few μT upto 10 T with 15N polarization of about 1-3%. Moreover, the investigated complex can be incorporated into biomolecules or other bulky molecules; in this situation exchange with para-hydrogen will allow one to continuously generate hyperpolarization.

AB - A strong limitation of nuclear magnetic resonance is its low inherent sensitivity that can be overcome by using an appropriate hyperpolarization technique. Presently, dynamic nuclear polarization and spin-exchange optical pumping are the only hyperpolarization techniques that are used in applied medicine. However, both are relatively complex in use and expensive. Here we present a modification of the signal amplification by reversible exchange (SABRE) hyperpolarization method-SABRE on stabilized Ir-complexes. A stabilized Ir-complex (here we used bipyridine for stabilization) can be hyperpolarized in a wide range of magnetic fields from a few μT upto 10 T with 15N polarization of about 1-3%. Moreover, the investigated complex can be incorporated into biomolecules or other bulky molecules; in this situation exchange with para-hydrogen will allow one to continuously generate hyperpolarization.

KW - bipyridine

KW - NMR

KW - para-hydrogen

KW - SABRE

KW - PARA-HYDROGEN

KW - LEVEL ANTI-CROSSINGS

KW - RESONANCE

KW - SPIN HYPERPOLARIZATION

KW - PARAHYDROGEN

KW - POLARIZATION TRANSFER

KW - CATALYSTS

KW - SIGNAL AMPLIFICATION

UR - http://www.scopus.com/inward/record.url?scp=85012283678&partnerID=8YFLogxK

U2 - 10.1515/zpch-2016-0810

DO - 10.1515/zpch-2016-0810

M3 - Article

AN - SCOPUS:85012283678

VL - 231

SP - 497

EP - 511

JO - Zeitschrift fur Physikalische Chemie

JF - Zeitschrift fur Physikalische Chemie

SN - 0942-9352

IS - 3

ER -

ID: 10310256