Research output: Contribution to journal › Article › peer-review
Rdbms And Nosql Based Hybrid Technology for Transcriptome Data Structuring and Processing. / Mukhin, A. M.; Genaev, M. A.; Rasskazov, D. A. et al.
In: Mathematical Biology and Bioinformatics, Vol. 15, No. 2, 2020, p. 455-470.Research output: Contribution to journal › Article › peer-review
}
TY - JOUR
T1 - Rdbms And Nosql Based Hybrid Technology for Transcriptome Data Structuring and Processing
AU - Mukhin, A. M.
AU - Genaev, M. A.
AU - Rasskazov, D. A.
AU - Lashin, S. A.
AU - Afonnikov, D. A.
N1 - Publisher Copyright: © 2020. All Rights Reserved. Copyright: Copyright 2021 Elsevier B.V., All rights reserved.
PY - 2020
Y1 - 2020
N2 - The transcriptome sequencing experiment (RNA-seq) has become almost a routine procedure for studying both model organisms and crops. As a result of bioinformatics processing of such experimental output, huge heterogeneous data are obtained, representing nucleotide sequences of transcripts, amino acid sequences, and their structural and functional annotation. It is important to present the data obtained to a wide range of researchers in the form of databases. This article proposes a hybrid approach to creating molecular genetic databases that contain information about transcript sequences and their structural and functional annotation. The essence of the approach consists in the simultaneous storing both structured and weakly structured data in the database. The technology was used to implement a database of transcriptomes of agricultural plants. This paper discusses the features of implementing this approach and examples of generating both simple and complex queries to such a database in the SQL language. The OORT database is freely available at https://oort.cytogen.ru/
AB - The transcriptome sequencing experiment (RNA-seq) has become almost a routine procedure for studying both model organisms and crops. As a result of bioinformatics processing of such experimental output, huge heterogeneous data are obtained, representing nucleotide sequences of transcripts, amino acid sequences, and their structural and functional annotation. It is important to present the data obtained to a wide range of researchers in the form of databases. This article proposes a hybrid approach to creating molecular genetic databases that contain information about transcript sequences and their structural and functional annotation. The essence of the approach consists in the simultaneous storing both structured and weakly structured data in the database. The technology was used to implement a database of transcriptomes of agricultural plants. This paper discusses the features of implementing this approach and examples of generating both simple and complex queries to such a database in the SQL language. The OORT database is freely available at https://oort.cytogen.ru/
KW - crops
KW - database
KW - indexing
KW - NoSQL
KW - plants
KW - queries
KW - RDBMS
KW - SQL
KW - transcriptomes
UR - http://www.scopus.com/inward/record.url?scp=85099614614&partnerID=8YFLogxK
U2 - 10.17537/2020.15.455
DO - 10.17537/2020.15.455
M3 - Article
AN - SCOPUS:85099614614
VL - 15
SP - 455
EP - 470
JO - Mathematical Biology and Bioinformatics
JF - Mathematical Biology and Bioinformatics
SN - 1994-6538
IS - 2
ER -
ID: 27527709