On-target CRISPR/CAS9 activity can cause undesigned large deletion in mouse zygotes

Original language	English
Article number	3604
Number of pages	14
Journal	International Journal of Molecular Sciences
Volume	21
Issue number	10
DOIs	https://doi.org/10.3390/ijms21103604
Publication status	Published - 20 May 2020

CRISPR/Cas9, Cytoplasmic microinjections, Kit knockout mice, Large deletion, On-target deletions, Truncation, Zygotic microinjections, CRISPR, VARIANTS, KIT GENE, DOMINANT-WHITE, large deletion, on-target deletions, GENOME, cytoplasmic microinjections, ONE-STEP GENERATION, DELIVERY, zygotic microinjections, CRISPR-CAS9 NUCLEASES, CAS9 RIBONUCLEOPROTEIN, MICE, Cas9, MUTATIONS, truncation

ID: 24397719