Neandertal and Denisovan DNA from Pleistocene sediments

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Neandertal and Denisovan DNA from Pleistocene sediments. / Slon, Viviane; Hopfe, Charlotte; Weiß, Clemens L. et al.

In: Science, Vol. 356, No. 6338, 12.05.2017, p. 605-608.

Research output: Contribution to journal › Article › peer-review

Harvard

Slon, V, Hopfe, C, Weiß, CL, Mafessoni, F, De La Rasilla, M, Lalueza-Fox, C, Rosas, A, Soressi, M, Knul, MV, Miller, R, Stewart, JR, Derevianko, AP, Jacobs, Z, Li, B, Roberts, RG, Shunkov, MV, De Lumley, H, Perrenoud, C, Gušić, I, Kućan, Ž, Rudan, P, Aximu-Petri, A, Essel, E, Nagel, S, Nickel, B, Schmidt, A, Prüfer, K, Kelso, J, Burbano, HA, Pääbo, S & Meyer, M 2017, 'Neandertal and Denisovan DNA from Pleistocene sediments', Science, vol. 356, no. 6338, pp. 605-608. https://doi.org/10.1126/science.aam9695

APA

Slon, V., Hopfe, C., Weiß, C. L., Mafessoni, F., De La Rasilla, M., Lalueza-Fox, C., Rosas, A., Soressi, M., Knul, M. V., Miller, R., Stewart, J. R., Derevianko, A. P., Jacobs, Z., Li, B., Roberts, R. G., Shunkov, M. V., De Lumley, H., Perrenoud, C., Gušić, I., ... Meyer, M. (2017). Neandertal and Denisovan DNA from Pleistocene sediments. Science, 356(6338), 605-608. https://doi.org/10.1126/science.aam9695

Vancouver

Slon V, Hopfe C, Weiß CL, Mafessoni F, De La Rasilla M, Lalueza-Fox C et al. Neandertal and Denisovan DNA from Pleistocene sediments. Science. 2017 May 12;356(6338):605-608. doi: 10.1126/science.aam9695

Author

Slon, Viviane ; Hopfe, Charlotte ; Weiß, Clemens L. et al. / Neandertal and Denisovan DNA from Pleistocene sediments. In: Science. 2017 ; Vol. 356, No. 6338. pp. 605-608.

BibTeX

@article{697fd9fc28684828ba1bec9061cd2023,

title = "Neandertal and Denisovan DNA from Pleistocene sediments",

abstract = "Although a rich record of Pleistocene human-associated archaeological assemblages exists, the scarcity of hominin fossils often impedes the understanding of which hominins occupied a site. Using targeted enrichment of mitochondrial DNA, we show that cave sediments represent a rich source of ancient mammalian DNA that often includes traces of hominin DNA, even at sites and in layers where no hominin remains have been discovered. By automation-assisted screening of numerous sediment samples, we detected Neandertal DNA in eight archaeological layers from four caves in Eurasia. In Denisova Cave, we retrieved Denisovan DNA in a Middle Pleistocene layer near the bottom of the stratigraphy. Our work opens the possibility of detecting the presence of hominin groups at sites and in areas where no skeletal remains are found.",

keywords = "Animals, Caves, DNA, Ancient/analysis, DNA, Mitochondrial/analysis, Europe, Fossils, Geologic Sediments/chemistry, Hominidae/classification, Sequence Analysis, DNA, PLANT, MAMMOTH, ANCIENT DNA, CAVE ALTAI MOUNTAINS, SIBERIA, GENOME SEQUENCE, EXTINCTION, HOMININ, REMAINS, HISTORY",

author = "Viviane Slon and Charlotte Hopfe and Wei{\ss}, {Clemens L.} and Fabrizio Mafessoni and {De La Rasilla}, Marco and Carles Lalueza-Fox and Antonio Rosas and Marie Soressi and Knul, {Monika V.} and Rebecca Miller and Stewart, {John R.} and Derevianko, {Anatoly P.} and Zenobia Jacobs and Bo Li and Roberts, {Richard G.} and Shunkov, {Michael V.} and {De Lumley}, Henry and Christian Perrenoud and Ivan Gu{\v s}i{\'c} and {\v Z}eljko Ku{\'c}an and Pavao Rudan and Ayinuer Aximu-Petri and Elena Essel and Sarah Nagel and Birgit Nickel and Anna Schmidt and Kay Pr{\"u}fer and Janet Kelso and Burbano, {Hern{\'a}n A.} and Svante P{\"a}{\"a}bo and Matthias Meyer",

year = "2017",

month = may,

day = "12",

doi = "10.1126/science.aam9695",

language = "English",

volume = "356",

pages = "605--608",

journal = "Science",

issn = "0036-8075",

publisher = "American Association for the Advancement of Science",

number = "6338",

}

RIS

TY - JOUR

T1 - Neandertal and Denisovan DNA from Pleistocene sediments

AU - Slon, Viviane

AU - Hopfe, Charlotte

AU - Weiß, Clemens L.

AU - Mafessoni, Fabrizio

AU - De La Rasilla, Marco

AU - Lalueza-Fox, Carles

AU - Rosas, Antonio

AU - Soressi, Marie

AU - Knul, Monika V.

AU - Miller, Rebecca

AU - Stewart, John R.

AU - Derevianko, Anatoly P.

AU - Jacobs, Zenobia

AU - Li, Bo

AU - Roberts, Richard G.

AU - Shunkov, Michael V.

AU - De Lumley, Henry

AU - Perrenoud, Christian

AU - Gušić, Ivan

AU - Kućan, Željko

AU - Rudan, Pavao

AU - Aximu-Petri, Ayinuer

AU - Essel, Elena

AU - Nagel, Sarah

AU - Nickel, Birgit

AU - Schmidt, Anna

AU - Prüfer, Kay

AU - Kelso, Janet

AU - Burbano, Hernán A.

AU - Pääbo, Svante

AU - Meyer, Matthias

PY - 2017/5/12

Y1 - 2017/5/12

N2 - Although a rich record of Pleistocene human-associated archaeological assemblages exists, the scarcity of hominin fossils often impedes the understanding of which hominins occupied a site. Using targeted enrichment of mitochondrial DNA, we show that cave sediments represent a rich source of ancient mammalian DNA that often includes traces of hominin DNA, even at sites and in layers where no hominin remains have been discovered. By automation-assisted screening of numerous sediment samples, we detected Neandertal DNA in eight archaeological layers from four caves in Eurasia. In Denisova Cave, we retrieved Denisovan DNA in a Middle Pleistocene layer near the bottom of the stratigraphy. Our work opens the possibility of detecting the presence of hominin groups at sites and in areas where no skeletal remains are found.

AB - Although a rich record of Pleistocene human-associated archaeological assemblages exists, the scarcity of hominin fossils often impedes the understanding of which hominins occupied a site. Using targeted enrichment of mitochondrial DNA, we show that cave sediments represent a rich source of ancient mammalian DNA that often includes traces of hominin DNA, even at sites and in layers where no hominin remains have been discovered. By automation-assisted screening of numerous sediment samples, we detected Neandertal DNA in eight archaeological layers from four caves in Eurasia. In Denisova Cave, we retrieved Denisovan DNA in a Middle Pleistocene layer near the bottom of the stratigraphy. Our work opens the possibility of detecting the presence of hominin groups at sites and in areas where no skeletal remains are found.

KW - Animals

KW - Caves

KW - DNA, Ancient/analysis

KW - DNA, Mitochondrial/analysis

KW - Europe

KW - Fossils

KW - Geologic Sediments/chemistry

KW - Hominidae/classification

KW - Sequence Analysis, DNA

KW - PLANT

KW - MAMMOTH

KW - ANCIENT DNA

KW - CAVE ALTAI MOUNTAINS

KW - SIBERIA

KW - GENOME SEQUENCE

KW - EXTINCTION

KW - HOMININ

KW - REMAINS

KW - HISTORY

UR - http://www.scopus.com/inward/record.url?scp=85018442438&partnerID=8YFLogxK

U2 - 10.1126/science.aam9695

DO - 10.1126/science.aam9695

M3 - Article

C2 - 28450384

AN - SCOPUS:85018442438

VL - 356

SP - 605

EP - 608

JO - Science

JF - Science

SN - 0036-8075

IS - 6338

ER -

ID: 10260235